局部切除治療壺腹癌的臨床分析
[Abstract]:Objective to evaluate the clinical efficacy of local resection in the treatment of ampullary carcinoma and to explore the feasibility and rationality of local resection in the treatment of ampullary carcinoma. Methods the clinical and pathological data of 15 patients with ampullary carcinoma underwent local resection in our hospital from January 2002 to December 2013 were retrospectively analyzed. Results among the 15 patients, 4 (26.7%) were male and 11 (73.3%) were female. The average age was 55.5 years (36-76 years). There were 7 patients with painless jaundice, accounting for 46.7%. There were 3 patients with abdominal pain complicated with jaundice (20.0%), 3 cases with simple abdominal pain (20.0%), 1 case with anorexia (6.7cm), 15 cases with ampullary carcinoma (1.8 鹵1.45 cm in diameter). The pathological results were as follows: highly differentiated adenocarcinoma in 6 cases (33.3%), moderately differentiated adenocarcinoma in 2 cases (13.3%), poorly differentiated adenocarcinoma in 3 cases (20.0%), tubular choriocarcinoma in 1 case (6.7%), neuroendocrine carcinoma in 1 case (6.7%), atypical hyperplasia in 2 cases (13.3%). The operative time was 133 鹵35.9min and the intraoperative blood loss was 161 鹵96.9ml. The days of hospitalization were 22.4 鹵8.6 days. One patient had postoperative pyloric obstruction, one patient had incisional infection, and one patient had pulmonary infection. No biliary leakage, pancreatic leakage, biliary tract infection, hemorrhage, liver failure were found in other patients. Among the 15 cases, 12 cases were followed up, and no operative death was found. The 1 year, 3 year and 5 year survival rates were 83.3%, 75.0% and 58.3%, respectively. Conclusion Local resection can be used as an important operative method for the treatment of ampullary carcinoma. It has the advantages of small trauma, quick recovery, low mortality and low incidence of complications. The key to the treatment is to strictly and accurately grasp the indication of operation. Master surgical skills skillfully.
【學(xué)位授予單位】:寧夏醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2015
【分類號(hào)】:R735.0
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