【摘要】：晚期食管癌患者接受單純放療后的生存率不高,治療失敗的主要原因是局部未控和遠(yuǎn)處轉(zhuǎn)移�；熆善鸬教岣吣[瘤局部控制率、預(yù)防及治療腫瘤遠(yuǎn)處轉(zhuǎn)移的作用,其有效率為35%~55%。放化療聯(lián)合應(yīng)用于食管癌治療,既能增強(qiáng)腫瘤組織對(duì)放療的敏感性,又能提高化療藥物的治療效果;二者相互協(xié)同,共同阻滯腫瘤進(jìn)展及轉(zhuǎn)移,最終延長(zhǎng)患者的生存時(shí)間。因此,在同步放化療的基礎(chǔ)上優(yōu)化各種化療方案,成為了近年來局部晚期食管癌研究的熱點(diǎn)之一。本文即對(duì)不同化療方案在食管癌臨床應(yīng)用中的放療增效作用進(jìn)行綜述。
[Abstract]:The survival rate of patients with advanced esophageal cancer after radiotherapy alone was not high. The main causes of failure were local uncontrolled and distant metastasis. Chemotherapy can improve the local control rate of tumor, prevent and treat distant metastasis of tumor, its effective rate is 3555. The combination of radiotherapy and chemotherapy can not only enhance the sensitivity of tumor tissue to radiotherapy, but also improve the therapeutic effect of chemotherapeutic drugs. Therefore, the optimization of various chemotherapy protocols based on concurrent radiotherapy and chemotherapy has become one of the hotspots in the study of locally advanced esophageal cancer in recent years. This article reviews the synergistic effects of different chemotherapy regimens in the clinical application of esophageal cancer.
【作者單位】： 濟(jì)南大學(xué)山東省醫(yī)學(xué)科學(xué)院醫(yī)學(xué)與生命科學(xué)學(xué)院;山東大學(xué)附屬山東省腫瘤醫(yī)院放療科;
【分類號(hào)】：R735.1

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