【摘要】：目的:探討外周血中淋巴細(xì)胞與單核細(xì)胞比值(LMR)對原發(fā)性肝癌(PLC)根治性切除術(shù)后預(yù)后的預(yù)測價值。方法:收集接受肝癌根治性切除術(shù)且術(shù)前未接受其他治療的PLC患者447例的臨床及實驗室資料,根據(jù)術(shù)前外周血檢查結(jié)果計算LMR,繪制術(shù)前LMR診斷患者術(shù)后5 a生存狀態(tài)的ROC曲線,確定LMR診斷界值。采用Kaplan-Meier法和COX回歸模型分析PLC患者術(shù)后5 a生存的影響因素。結(jié)果:術(shù)前LMR診斷界值為3.03,據(jù)此將LMR分為高(≥3.03)和低(3.03)兩種狀態(tài)。COX分析結(jié)果顯示術(shù)前高LMR是PLC患者術(shù)后預(yù)后的保護(hù)因素(β=-0.329,HR=0.720,95%CI=0.562~0.921)。結(jié)論:術(shù)前LMR可用于評價PLC根治性切除術(shù)后患者的預(yù)后,術(shù)前高LMR患者預(yù)后較好。
[Abstract]:Objective: to investigate the prognostic value of lymphocyte to monocyte ratio (LMR) in peripheral blood in patients with primary liver cancer after (PLC) radical resection. Methods: the clinical and laboratory data of 447 PLC patients who underwent radical resection of liver cancer without other treatment were collected. According to the results of preoperative peripheral blood examination, LMR, was calculated to draw the ROC curve of the survival state of the patients diagnosed by LMR 5 years after operation. To determine the diagnostic limit of LMR. Kaplan-Meier method and COX regression model were used to analyze the factors influencing the survival of PLC patients 5 years after operation. Results: the diagnostic threshold of preoperative LMR was 3.03, according to which LMR was classified into high (鈮，

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