【摘要】：目的通過(guò)對(duì)74例胃神經(jīng)內(nèi)分泌腫瘤的發(fā)病、診斷、治療和預(yù)后的研究,進(jìn)一步加深對(duì)胃神經(jīng)內(nèi)分泌腫瘤的了解,提高胃神經(jīng)內(nèi)分泌腫瘤的診治水平方法回顧性分析2008年1月至2013年9月安徽醫(yī)科大學(xué)第一附屬醫(yī)院收治的74例胃神經(jīng)內(nèi)分泌腫瘤患者的臨床資料和隨訪結(jié)果,數(shù)據(jù)通過(guò)SPSS 16.0軟件處理,采用Kaplan-Meier法進(jìn)行單因素生存分析.結(jié)果74例胃神經(jīng)內(nèi)分泌腫瘤患者,平均年齡為62.86歲,男女比例2.52：1；首發(fā)癥狀以上腹不適為主的有48例(約占64.86%),進(jìn)食哽噎有21例(約28.38%),反酸暖氣、黑便、消瘦等癥狀的有12例(約占16.21%)。74例患者中,類癌5例,神經(jīng)內(nèi)分泌癌52例,神經(jīng)內(nèi)分泌瘤17例；一期6例、二期21例、三期28例、四期19例。57例患者接受根治性手術(shù)治療,12例患者接受姑息性手術(shù)治療,5例患者行化療。74例均獲得隨訪,全組1、3、5年存活率分別為74.32%(55/74)、40.54%(30/74)、18.91%(14/74)。結(jié)論胃神經(jīng)內(nèi)分泌腫瘤好發(fā)于男性,發(fā)病年齡較遲,癥狀不典型,盡早接受根治性手術(shù)治療能夠有效的提高患者的生存率。
[Abstract]:Objective to study the pathogenesis, diagnosis, treatment and prognosis of 74 cases of gastric neuroendocrine tumors. Methods the clinical data and follow-up results of 74 patients with gastric neuroendocrine tumors treated in the first affiliated Hospital of Anhui Medical University from January 2008 to September 2013 were analyzed retrospectively. The data were processed by SPSS 16.0 software, and single factor survival analysis was carried out by Kaplan-Meier method. Results the average age of 74 patients with gastric neuroendocrine neoplasms was 62.86 years old, the ratio of male and female was 2.52: 1, 48 cases (64.86%) had first symptoms of abdominal discomfort, 21 cases (28.38%) had choking on food, reflux and warm air, black stool. There were 12 cases (16.21%) with wasting and other symptoms, including 5 cases of carcinoid, 52 cases of neuroendocrine carcinoma, 17 cases of neuroendocrine tumor, 6 cases of primary stage, 21 cases of secondary stage, 28 cases of stage 3. Twelve patients received palliative operation and 5 patients received palliative operation. All patients were followed up. The survival rates of the patients were 74.32% (55 / 74) and 40.54% (30 / 74), respectively. The survival rate of the patients was 18.91% (14 / 74), and the survival rates were 74.32% (55 / 74) and 40.54% (30 / 74), respectively. Conclusion gastric neuroendocrine neoplasms are more common in men with late onset age and atypical symptoms. Radical surgical treatment as early as possible can effectively improve the survival rate of patients.
【學(xué)位授予單位】：安徽醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R735.2

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相關(guān)期刊論文 前1條

1 馮強(qiáng);鄭朝旭;馮曉莉;畢建軍;;胃神經(jīng)內(nèi)分泌腫瘤臨床病理特點(diǎn)及預(yù)后分析[J];中國(guó)普通外科雜志;2012年06期

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本文編號(hào)：2154300