化療方案及療程對(duì)乳腺癌患者體成分的影響
發(fā)布時(shí)間:2018-07-24 16:33
【摘要】:目的:研究不同方案和療程對(duì)乳腺癌患者體成分的影響。方法:利用前瞻性研究,間接計(jì)算出患者的腰臀比、腰圍身高比(WSR)、身體質(zhì)量指數(shù)(BMI)、體脂率、體脂肪和瘦體質(zhì)量等體質(zhì)指標(biāo)、體成分的含量。結(jié)果:不同療程的WSR、BMI、體脂、體脂率差異有統(tǒng)計(jì)學(xué)意義,BMI、體脂、體脂率與療程間的兩兩比較差異有統(tǒng)計(jì)學(xué)意義;WSR在表柔比星+環(huán)磷酰胺(EC)方案療程間(第一、二次化療比較除外)的兩兩比較差異有統(tǒng)計(jì)學(xué)意義,和多柔比星+環(huán)磷酰胺(AC)方案療程間(第一次與化療前,第二、三次療程比較除外)的兩兩比較差異有統(tǒng)計(jì)學(xué)意義。結(jié)論:EC方案中,BMI、WSR、體脂肪、體脂率隨療程進(jìn)展而增加;AC方案中,BMI、體脂肪、體脂率隨療程進(jìn)展先減少后增加,WSR隨療程進(jìn)展而增加。
[Abstract]:Objective: to study the effect of different regimens and courses on body composition of breast cancer patients. Methods: by using prospective study, the body fat ratio, body fat and lean body mass, body composition and body mass index (BMI),) of patients with waist hip ratio (WHR), waist height ratio (WSR), waist height ratio (WHR), and body mass index (BMI),) were calculated indirectly. Results: there was significant difference in body fat rate between different courses of WSRS BMIs and different courses of treatment. There was significant difference between body fat rate and course of treatment during the course of treatment with epirubicin cyclophosphamide (EC) regimen (1). The difference was statistically significant between the two groups except for the comparison of the second chemotherapy and doxorubicin cyclophosphamide (AC) regimen (except for the first and the second and third courses of chemotherapy). Conclusion the percentage of BMIWSR, body fat and body fat increased with the course of treatment. The percentage of body fat in AC regimen decreased firstly and then increased with the course of treatment.
【作者單位】: 錦州醫(yī)科大學(xué)附屬第一醫(yī)院;新鄉(xiāng)市中心醫(yī)院;新鄉(xiāng)醫(yī)學(xué)院第一附屬醫(yī)院;錦州醫(yī)科大學(xué)生物人類學(xué)研究所;
【基金】:國(guó)家自然科學(xué)基金(31571233)
【分類號(hào)】:R737.9
本文編號(hào):2141977
[Abstract]:Objective: to study the effect of different regimens and courses on body composition of breast cancer patients. Methods: by using prospective study, the body fat ratio, body fat and lean body mass, body composition and body mass index (BMI),) of patients with waist hip ratio (WHR), waist height ratio (WSR), waist height ratio (WHR), and body mass index (BMI),) were calculated indirectly. Results: there was significant difference in body fat rate between different courses of WSRS BMIs and different courses of treatment. There was significant difference between body fat rate and course of treatment during the course of treatment with epirubicin cyclophosphamide (EC) regimen (1). The difference was statistically significant between the two groups except for the comparison of the second chemotherapy and doxorubicin cyclophosphamide (AC) regimen (except for the first and the second and third courses of chemotherapy). Conclusion the percentage of BMIWSR, body fat and body fat increased with the course of treatment. The percentage of body fat in AC regimen decreased firstly and then increased with the course of treatment.
【作者單位】: 錦州醫(yī)科大學(xué)附屬第一醫(yī)院;新鄉(xiāng)市中心醫(yī)院;新鄉(xiāng)醫(yī)學(xué)院第一附屬醫(yī)院;錦州醫(yī)科大學(xué)生物人類學(xué)研究所;
【基金】:國(guó)家自然科學(xué)基金(31571233)
【分類號(hào)】:R737.9
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