本文選題：彌散張量成像 + 膠質(zhì)瘤　； 參考：《吉林大學學報(醫(yī)學版)》2017年02期

【摘要】：目的:采用Meta分析方法闡明彌散張量成像(DTI)的部分各項異性(FA值)值和表觀彌散系數(shù)(ADC)值在膠質(zhì)瘤分級中應用的意義,為膠質(zhì)瘤治療方案的選擇與預后判斷提供參考。方法:計算機檢索PubMed數(shù)據(jù)庫、EMBASE數(shù)據(jù)庫、中國知網(wǎng)(CNKI)、萬方數(shù)據(jù)庫和維普數(shù)據(jù)庫,手工檢索神經(jīng)外科學雜志、神經(jīng)影像學雜志和有關(guān)神經(jīng)外科的學術(shù)會議論文集,回溯檢索綜述性論文的參考文獻,按納入與排除標準選擇病例系列研究、評價研究質(zhì)量,采用Review Manager 5.2軟件對所提取數(shù)據(jù)進行Meta分析。結(jié)果:共有9篇文獻入選。低級別膠質(zhì)瘤(LGG)腫瘤實質(zhì)區(qū)的FA值低于高級別膠質(zhì)瘤(HGG)腫瘤實質(zhì)區(qū)的FA值,差異有統(tǒng)計學意義(χ~2=11.94,df=8,P=0.15;I~2=33%,Z=2.78,P=0.005;WMDFA值=-0.02,95%CI:-0.03~-0.01);LGG腫瘤實質(zhì)區(qū)的ADC值高于HGG腫瘤實質(zhì)區(qū)的ADC值,差異有統(tǒng)計學意義(χ~2=5.26,df=4,P=0.26;I~2=24%,Z=2.19,P=0.03;WMD_(ADC值)=0.15,95%CI:0.02~0.28)。結(jié)論:膠質(zhì)瘤實質(zhì)區(qū)FA值越大,ADC值越低,膠質(zhì)瘤的級別越高;DTI的FA值和ADC值有助于確定膠質(zhì)瘤的分級。
[Abstract]:Objective: to elucidate the value of partial heterosexual FA value and apparent diffusion coefficient of diffusion Zhang Liang imaging (DTI) in glioma grading by meta-analysis, so as to provide a reference for the treatment of glioma and the judgement of prognosis. Methods: PubMed database was searched by computer, CNKIX, Wanfang database and Weip database were searched by computer, neurosurgery journal, neuroimaging journal and proceedings of neurosurgery were searched by hand. Retrospective retrieval of the literature of summary papers, selection of case series studies according to inclusion and exclusion criteria, evaluation of research quality, Meta-analysis of extracted data using Review Manager 5.2 software. Results: a total of 9 articles were selected. 浣庣駭鍒兌璐ㄧ槫(LGG)鑲跨槫瀹炶川鍖虹殑FA鍊間綆浜庨珮綰у埆鑳惰川鐦，

本文編號：2029347