發(fā)布時間：2018-06-14 16:51

  本文選題：胰頭部腫瘤 + 姑息治療　； 參考：《臨床軍醫(yī)雜志》2016年11期

【摘要】：目的探討不同條件下的胰頭部腫瘤患者姑息治療的方法及治療效果。方法回顧性分析2005年1月至2015年12月在新疆醫(yī)科大學(xué)第一附屬醫(yī)院收治的139例胰頭部腫瘤患者的臨床資料。根據(jù)患者的不同條件分為可切除組(45例)和不可切除組(94例),根據(jù)治療方式不同將兩組細(xì)分為姑息手術(shù)組和支架組,共4個亞組。通過對生存時間及術(shù)后1個月白蛋白、總膽紅素、并發(fā)癥等指標(biāo)的觀察和對比分析,評價可切除組和不可切除組姑息手術(shù)治療的情況。結(jié)果本研究139例患者術(shù)后獲隨訪9~36個月�？汕谐M與不可切除組患者在住院時間方面比較,差異無統(tǒng)計學(xué)意義(P0.05);而在生存時間及術(shù)后1個月白蛋白、總膽紅素指標(biāo)方面比較,差異有統(tǒng)計學(xué)意義(P0.05)�？汕谐M中,姑息手術(shù)組患者中位生存期大于支架組(P0.05);不可切除組中,姑息手術(shù)組患者中位生存期小于支架組(P0.05)。結(jié)論對于胰頭部腫瘤可切除但放棄行胰十二指腸根治術(shù)者,治療方案更傾向于姑息手術(shù)治療;而對于不可切除者,治療方案更傾向于支架治療。
[Abstract]:Objective to investigate the methods and effect of palliative treatment of pancreatic head tumor patients under different conditions. Methods the clinical data of 139 patients with pancreatic head tumors admitted in the First Affiliated Hospital of Xinjiang Medical University from January 2005 to December 2015 were retrospectively analyzed. According to the different conditions, the patients were divided into excision group (45 cases) and non resectable group (94 According to the different treatment methods, two groups were divided into palliative operation group and stent group, 4 subgroups. Through observation and comparison of survival time and 1 months postoperatively albumin, total bilirubin, complications and other indexes, the treatment of excision group and unresectable group palliative treatment were evaluated. Results 139 patients were followed up 9 after operation. ~36 months. There was no significant difference in the time of hospitalization between the excision group and the non resectable group (P0.05), but there was a significant difference in the survival time and the total bilirubin index in the 1 months after the operation (P0.05). In the resectable group, the median survival time of the palliative group was greater than that of the stent group (P0.05); In the group, the median survival time of the patients in the palliative operation group was less than that of the stent group (P0.05). Conclusion the treatment scheme is more inclined to palliative surgery for the resection of the head of the pancreas but abandons the radical pancreatoduodenectomy, but for the non resectable, the treatment scheme is more inclined to the stent treatment.
【作者單位】： 新疆醫(yī)科大學(xué)第一附屬醫(yī)院胰腺外科;
【分類號】：R735.9

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本文編號：2018229