本文選題：肝細(xì)胞性肝癌 + 射頻輔助肝切除術(shù)��； 參考：《第三軍醫(yī)大學(xué)》2015年碩士論文

【摘要】：目的前瞻性比較射頻輔助肝切除術(shù)與單純性肝切除術(shù)在治療肝細(xì)胞性肝癌的圍手術(shù)期療效。方法通過運(yùn)用前瞻性隨機(jī)對照研究的方法,我們在2012年12月至2014年10月期間第三軍醫(yī)大學(xué)第一附屬醫(yī)院肝膽外科收治的肝癌患者中,一共將92例肝細(xì)胞性肝癌的患者隨機(jī)性地分配到兩個治療組中,其中單純性肝切除術(shù)組(LR)有46例,射頻輔助肝切除術(shù)組(RF+LR)有46例。主要觀察指標(biāo)包括各組患者術(shù)中的出血量和肝門阻斷時間;次要觀察指標(biāo)是患者術(shù)后的肝功能、并發(fā)癥發(fā)生率、死亡率、住院時間。結(jié)果射頻輔助肝切除術(shù)組(RF+LR)與單純性肝切除術(shù)組(LR)在平均失血量方面,RF+LR組顯著減少(300 vs 400ml,P=0.049);肝門阻斷的時間在RF+LR組明顯降低(10 vs 15min,P=0.014)。術(shù)后肝功能和總體的并發(fā)癥發(fā)生率兩組間無統(tǒng)計(jì)學(xué)差異,住院時間RF+LR組明顯縮短(18.5 vs 22.5天,P=0.002)。兩組均無死亡的患者。結(jié)論射頻輔助肝切除術(shù)在肝細(xì)胞性肝癌的治療中能夠有效的減少術(shù)中出血量、肝門阻斷時間和住院時間,對于合并肝硬化重的患者應(yīng)慎用該方法。
[Abstract]:Objective to compare the perioperative efficacy of radiofrequency assisted hepatectomy and simple hepatectomy in the treatment of hepatocellular carcinoma. Methods from December 2012 to October 2014, we used a prospective randomized controlled study of liver cancer patients admitted to the first affiliated Hospital of the third military Medical University in the department of hepatobiliary surgery. A total of 92 patients with hepatocellular carcinoma were randomly assigned to two treatment groups: 46 cases in simple hepatectomy group and 46 cases in radiofrequency assisted hepatectomy group. The main outcome measures were the amount of blood loss during operation and the time of hepatic hilus occlusion. The secondary indexes were liver function, incidence of complications, mortality rate and hospitalization time. Results the mean blood loss in radiofrequency assisted hepatectomy group and simple hepatectomy group was significantly lower than that in RF LR group (300 vs 400 ml / L), and the time of hepatic hilus occlusion in RF LR group was significantly lower than that in RF LR group (n = 10 vs 15 min, P < 0. 014). There was no significant difference in postoperative liver function and overall incidence of complications between the two groups. The length of stay in the RF LR group was significantly shorter than that in the RF LR group (18.5 vs 22.5 days). There was no death in both groups. Conclusion radiofrequency assisted hepatectomy can effectively reduce intraoperative blood loss, hepatic portal occlusion time and hospitalization time in the treatment of hepatocellular carcinoma. This method should be used with caution in patients with severe liver cirrhosis.
【學(xué)位授予單位】：第三軍醫(yī)大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R735.7

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 Spiros G Delis;Juan Madariaga;A Bakoyiannis;Ch Dervenis;;Current role of bloodless liver resection[J];World Journal of Gastroenterology;2007年06期

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本文編號：1950644