3.0T磁共振體素內(nèi)不相干運(yùn)動(dòng)擴(kuò)散加權(quán)成像鑒別診斷脊柱不典型血管瘤與溶骨性轉(zhuǎn)移瘤
發(fā)布時(shí)間:2018-05-19 14:09
本文選題:脊柱 + 血管瘤; 參考:《中國(guó)醫(yī)學(xué)影像技術(shù)》2017年02期
【摘要】:目的探討3.0T MR體素內(nèi)不相干運(yùn)動(dòng)(IVIM)成像對(duì)脊柱不典型血管瘤與溶骨性轉(zhuǎn)移瘤的鑒別診斷價(jià)值。方法回顧性收集18例脊柱不典型血管瘤患者(19個(gè)病灶)和25例脊柱轉(zhuǎn)移瘤患者(69個(gè)病灶)。對(duì)所有患者均行3.0T MR掃描,包括常規(guī)序列和IVIM DWI序列,采用單指數(shù)模型后處理軟件獲得ADC值,采用雙指數(shù)模型后處理軟件獲得IVIM參數(shù),包括慢速擴(kuò)散系數(shù)(ADCslow值)、快速擴(kuò)散系數(shù)(ADCfast值)及快速擴(kuò)散分?jǐn)?shù)(f值)。采用獨(dú)立樣本t檢驗(yàn)或Mann-Whitney U檢驗(yàn)比較各參數(shù)值的差異。結(jié)果脊柱不典型血管瘤和轉(zhuǎn)移瘤的ADC值分別為(1.16±0.30)×10~(-3) s/mm~2、(0.80±0.27)×10~(-3) s/mm~2,差異有統(tǒng)計(jì)學(xué)意義(t=5.00,P0.001);ADCslow中位數(shù)分別為0.78×10~(-3) s/mm~2、0.55×10~(-3) s/mm~2,差異有統(tǒng)計(jì)學(xué)意義(P=0.02);ADCfast分別為(63.06±33.89)×10~(-3) s/mm~2、(70.78±39.62)×10~(-3) s/mm~2,差異無統(tǒng)計(jì)學(xué)意義(t=0.77,P=0.44);f分別為(40.65±14.75)%、(32.49±11.50)%,差異有統(tǒng)計(jì)學(xué)意義(t=2.57,P=0.01)。結(jié)論 IVIM可定量評(píng)估脊柱不典型血管瘤和溶骨性轉(zhuǎn)移瘤的水分子擴(kuò)散及微血管灌注特性,ADC、ADCslow值對(duì)脊柱不典型血管瘤和溶骨性轉(zhuǎn)移瘤具有一定的鑒別診斷價(jià)值。
[Abstract]:Objective to evaluate the value of 3. 0T Mr VIM imaging in differential diagnosis of spinal atypical hemangioma and osteolytic metastasis. Methods 18 patients with atypical spinal hemangioma (19 lesions) and 25 patients with spinal metastases (69 lesions) were retrospectively collected. All patients were scanned with 3.0T Mr scan, including routine sequence and IVIM DWI sequence. The ADC value was obtained by single exponential model post-processing software, and the IVIM parameters were obtained by double-exponential model post-processing software. These include slow diffusion coefficient (ADCD), fast diffusion coefficient (ADCfast) and fast diffusion fraction (f). T test and Mann-Whitney U test were used to compare the difference of parameters. 緇撴灉鑴婃煴涓嶅吀鍨嬭綆$槫鍜岃漿縐葷槫鐨凙DC鍊煎垎鍒負(fù)(1.16鹵0.30)脳10~(-3) s/mm~2,(0.80鹵0.27)脳10~(-3) s/mm~2,宸紓鏈夌粺璁″鎰忎箟(t=5.00,P0.001);ADCslow涓綅鏁板垎鍒負(fù)0.78脳10~(-3) s/mm~2,0.55脳10~(-3) s/mm~2,宸紓鏈夌粺璁″鎰忎箟(P=0.02);ADCfast鍒嗗埆涓,
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