本文選題：低氮低熱量 + 傳統(tǒng)氮熱量��； 參考：《南昌大學》2015年碩士論文

【摘要】：目的:研究低氮低熱量腸外營養(yǎng)對胃癌患者術后血糖、營養(yǎng)、免疫、炎癥反應及術后恢復的影響,并探討低氮低熱量腸外營養(yǎng)支持方案對胃癌術后患者的臨床應用。方法:將58例胃癌患者隨機分為低氮低熱量腸外營養(yǎng)組和傳統(tǒng)氮熱量腸外營養(yǎng)組,分別在術后第1天至第5天給予相應熱量和氮量的腸外營養(yǎng)支持,并于術前、術后檢測患者血糖、營養(yǎng)、免疫、C反應蛋白指標及觀察患者術后恢復情況。結(jié)果:(1)低氮低熱量PN組術后血糖控制明顯優(yōu)于傳統(tǒng)氮熱量PN組,術后第一天、術后第二天、術后第三天及術后第四天患者血糖水平差異有統(tǒng)計學意義(P0.05),而術前第一天及術后第五天兩組患者血糖水平均無統(tǒng)計學意義(P0.05)。(2)兩組患者術后均存在負氮平衡,兩組患者術前、術后的營養(yǎng)指標如白蛋白、前白蛋白及視黃醇蛋白,其差異均無統(tǒng)計學意義(P0.05)。(3)術前一天及術后第六天兩組患者免疫指標無統(tǒng)計學差異(P0.05)。(4)兩組患者術前一天及術后第三天C反應蛋白差異無統(tǒng)計學意義(p0.05),而術后第六天兩組患者的C反應蛋白差異有統(tǒng)計學意義(P0.05)。(5)低氮低熱量PN組術后感染率低于傳統(tǒng)氮熱量PN組,兩組感染例數(shù)差異無統(tǒng)計學意義。(6)兩組患者術后肛門排氣時間、切口拆線時間及術后住院時間差異無統(tǒng)計學意義(P0.05)。結(jié)論:低氮低熱量腸外營養(yǎng)支持方案對胃癌患者術后短期應用具有可行性,同時能更好的穩(wěn)定患者術后血糖水平,可能降低術后感染率,減輕機體急性炎性反應,并有可能促進患者術后康復。
[Abstract]:Objective: to study the effects of low nitrogen and low calorie parenteral nutrition on postoperative blood glucose, nutrition, immunity, inflammatory reaction and postoperative recovery in patients with gastric cancer, and to explore the clinical application of low nitrogen and low calorie parenteral nutrition in patients with gastric cancer after operation. Methods: Fifty-eight patients with gastric cancer were randomly divided into low nitrogen and low calorie parenteral nutrition group and traditional nitrogen caloric parenteral nutrition group. Blood glucose, nutrition, immuno-C reactive protein index and postoperative recovery were observed. Results (1) the control of blood glucose in low nitrogen and low calorie PN group was significantly better than that in traditional nitrogen calorie PN group, the first day and the second day after operation. On the third day and the fourth day after operation, there was a significant difference in blood glucose levels between the two groups (P 0.05), but there was no significant difference in blood glucose levels between the two groups on the first day of operation and on the fifth day after operation. Postoperative nutritional indicators such as albumin, prealbumin and retinol protein, There was no significant difference in immunological indexes between the two groups on the first day before operation and on the sixth day after operation. (P 0.05) there was no significant difference in C-reactive protein between the two groups on the first day before operation and on the third day after operation, but there was no significant difference in C-reactive protein between the two groups on the sixth day after operation. The infection rate of low nitrogen and low calorie PN group was lower than that of traditional nitrogen calorie PN group. There was no significant difference in the number of infection cases between the two groups. (6) there was no significant difference in postoperative anal exhaust time, incision removal time and postoperative hospitalization time between the two groups (P 0.05). Conclusion: low nitrogen and low calorie parenteral nutrition support regimen is feasible for patients with gastric cancer. It can stabilize blood glucose level, reduce postoperative infection rate and alleviate acute inflammatory reaction. It is possible to promote postoperative recovery of patients.
【學位授予單位】：南昌大學
【學位級別】：碩士
【學位授予年份】：2015
【分類號】：R735.2;R459.3

【參考文獻】

相關期刊論文 前10條

1 康凱;舒曉亮;姬舒榮;鐘靜霞;王銘河;張勇勝;唐大寒;;低氮低熱量腸外營養(yǎng)對腹部手術病人療效及預后影響的Meta分析[J];腸外與腸內(nèi)營養(yǎng);2013年06期

2 ;《2012中國腫瘤登記年報》發(fā)布[J];抗癌之窗;2013年02期

3 周宏;周曉聰;夏建福;楊大慶;方陽;李日增;;低氮低熱量腸外營養(yǎng)對腹腔鏡大腸癌術后患者短期療效的影響[J];中華實驗外科雜志;2012年09期

4 王尚前;邵國安;張虎;劉貴峰;;低氮低熱量腸外營養(yǎng)臨床應用價值的系統(tǒng)評價[J];中國全科醫(yī)學;2012年02期

5 全曉明;劉立;何小軍;王東峰;彭露;張冬;;低氮低熱卡腸外營養(yǎng)聯(lián)合激素治療在胃腸道腫瘤患者術后的應用[J];中華實驗外科雜志;2011年05期

6 王榮朝;陳煥年;王R，

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