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2013年-2016年廣西醫(yī)科大學第一附屬醫(yī)院非小細胞肺癌患者人群特征分析

發(fā)布時間:2018-05-02 00:09

  本文選題:非小細胞肺癌 + 人群特征 ; 參考:《廣西醫(yī)科大學》2017年碩士論文


【摘要】:目的:肺癌是我國常見的惡性腫瘤之一,其中以非小細胞肺癌多見。本研究通過對2013年至2016年于廣西醫(yī)科大學第一附屬醫(yī)院住院的非小細胞肺癌患者的人群特征進行回顧性分析,以初步了解近年來非小細胞肺癌的人群特點。方法:收集2013年至2016年于廣西醫(yī)科大學第一附屬醫(yī)院住院的非小細胞肺癌患者住院病例,對其中的男女比例、年齡分布、病人來源、吸煙史、民族、病理類型、臨床分期等臨床資料進行對比分析。結果:收集非小細胞肺癌病例共2,564例,其中2013年568例,2014年635例,2015年669例,2016年692例。男性患者1,699例,女性患者865例,男女比例為1.96:1。年齡段在50-59歲的患者最多,為828例,占32.29%。女性患者在該年齡段病例數最多,為277例,占女性患者病例數的32.02%。男性患者在60-69歲年齡段最多,為571例,占男性患者病例數的33.61%。非小細胞肺癌患者以腺癌最多見,在各病理類型中占71.41%。腺癌在2013年-2016年的構成比分別是:67.61%、71.81%、70.85%、74.71%。腺癌患者的男女構成比為59.64%,40.36%,鱗癌患者的男女構成比為85.16%,14.84%。腺癌于各年齡段中構成比分別為81.05%、72.67%、71.50%、70.05%、66.44%、86.67%。2,564例非小細胞肺癌患者中,吸煙患者為1,207例(47%),非吸煙患者1,357例(53%)。吸煙與非吸煙患者中,病理類型均以腺癌多見,吸煙者中的腺癌病例為708例(58.66%),非吸煙患者中的腺癌病例為1123例(82.76%)。壯族患者中以腺癌居多,占74.39%。廣西地區(qū)患者多數來自南寧,占30.89%,病理類型以腺癌為主。在具有明確TNM分期及臨床分期的1,931例非小細胞肺癌患者中,臨床分期為Ⅲb、Ⅳ期的病例數最多,為1,205例,占62.40%。結論:近四年于我院住院的確診為非小細胞肺癌患者呈現逐年增多趨勢,其中以男性患者多見,中老年患者居多,大多數病人確診時已處于晚期。在本研究的非小細胞肺癌患者中,病理類型以腺癌為主,占71.41%,其構成比大致呈現逐年升高趨勢。吸煙與非吸煙患者中,病理類型均以腺癌多見。吸煙患者的鱗癌患者構成比高于非吸煙患者,提示吸煙與鱗癌關系密切。壯族非小細胞肺癌患者中以腺癌居多,病理類型分布與漢族患者相比存在明顯差異。
[Abstract]:Objective: lung cancer is one of the most common malignant tumors in China. In this study, the population characteristics of non-small cell lung cancer (NSCLC) patients hospitalized in the first affiliated Hospital of Guangxi Medical University from 2013 to 2016 were analyzed retrospectively to understand the population characteristics of NSCLC in recent years. Methods: the inpatients with non-small cell lung cancer (NSCLC) hospitalized in the first affiliated Hospital of Guangxi Medical University from 2013 to 2016 were collected. The male and female ratio, age distribution, patient origin, smoking history, ethnicity, pathological type of NSCLC were analyzed. The clinical data such as clinical staging were compared and analyzed. Results: 2564 cases of NSCLC were collected, including 568 cases in 2013, 635 cases in 2014, 669 cases in 2015 and 692 cases in 2016. There were 1699 males and 865 females, with a ratio of 1.96: 1. Patients aged 50-59 years were the most, 828 cases (32.29%). The largest number of female patients in this age group, 277 cases, accounted for 32. 02% of female cases. Male patients were the most in the 60-69 age group, accounting for 571 cases, accounting for 33.61% of male cases. Adenocarcinoma is the most common type of non-small cell lung cancer, accounting for 71. 41% of the pathological types. The constitution of adenocarcinoma in 2013-2016 is: 67.61 / 71.81 / 70.85 / 74.71 respectively. The ratio of male to female was 59.64% in adenocarcinoma and 14.84 in squamous cell carcinoma. The constituent ratio of adenocarcinoma in each age group was 81.05 and 71.50 respectively. The ratio of 70.055.66.44and 86.67.2564 cases of non-small cell lung cancer was 86.67.2564, of which 1207 were smoking patients and 1357 were non-smoking patients. Adenocarcinoma was the most common pathological type in smoking and non-smoking patients. There were 708 cases of adenocarcinoma in smokers and 1123 cases of adenocarcinoma in non-smoking patients. The majority of Zhuang patients were adenocarcinoma (74.39%). Most of the patients in Guangxi were from Nanning (30.89%), and adenocarcinoma was the main pathological type. Among the 1931 cases of non-small cell lung cancer with definite TNM staging and clinical staging, the clinical stage 鈪,

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