本文選題：食管癌 + 食管切除術(shù)　； 參考：《新疆醫(yī)科大學(xué)》2015年碩士論文

【摘要】：目的：比較食管癌切除手術(shù)Ivor-Lewis術(shù)式與Sweet術(shù)式的有效性和安全性,探討食管癌切除術(shù)的最佳手術(shù)方式。方法：檢索PubMed、EMbase、the Cochrane Library、 Google scholar、中國知網(wǎng)(CNKI)、中國生物醫(yī)學(xué)文獻(xiàn)總庫(CBM)、維普數(shù)據(jù)庫(VIP)及萬方數(shù)據(jù)庫公開發(fā)表的Ivor-Lewis術(shù)式與Sweet術(shù)式比較的研究,采用RevMan 5.3軟件進(jìn)行數(shù)據(jù)分析。結(jié)果：14篇文獻(xiàn)共3922例患者納入研究,其中Ivor-Lewis組1322例,Sweet組2600例。Meta分析結(jié)果顯示,與Sweet組比較,Ivor-Lewis組手術(shù)時(shí)間明顯較長(MD=57.40,95%CI:42.43～72.38,P=0.000),手術(shù)出血量明顯較高(MD=28.39,95%CI:4.06～52.72,P=0.02),淋巴結(jié)清掃數(shù)目明顯較多(MD=4.19,95%CI:3.06～5.32,P=0.000);兩組喉返神經(jīng)損傷、乳糜胸、肺部并發(fā)癥和吻合口瘺等并發(fā)癥的發(fā)生情況差異無統(tǒng)計(jì)學(xué)意義(均P0.05)；兩組間5年生存率差異無統(tǒng)計(jì)學(xué)意義(P=0.60)。結(jié)論：兩種術(shù)式遠(yuǎn)期療效相當(dāng),Sweet術(shù)式較Ivor-Lewis術(shù)式操作方便,節(jié)省手術(shù)時(shí)間,患者耐受性較好；Ivor-Lewis術(shù)式比Sweet術(shù)式能夠清掃更多的淋巴結(jié),亦未增加術(shù)后并發(fā)癥。
[Abstract]:Objective: To compare the effectiveness and safety of Ivor-Lewis and Sweet in resection of esophageal cancer, and to explore the best surgical methods for esophagectomy. Methods: retrieve PubMed, EMbase, the Cochrane Library, Google scholar, Chinese knowledge network (CNKI), Chinese biologic Library (CBM), VP database (VIP) and Wanfang database. The study of the comparison of Ivor-Lewis and Sweet by RevMan 5.3 software was used to analyze the data. Results: 3922 patients in 14 papers were included in the study, of which 1322 cases were in group Ivor-Lewis, and 2600 cases in group Sweet showed that compared with group Sweet, the operation time of Ivor-Lewis group was significantly longer (MD=57.40,95%CI:42.43 ~ 72.38). P=0.000), the amount of bleeding was significantly higher (MD=28.39,95%CI:4.06 ~ 52.72, P=0.02), and the number of lymph nodes was significantly higher (MD=4.19,95%CI:3.06 ~ 5.32, P=0.000), and there was no significant difference between the two groups of recurrent laryngeal nerve injury, chylothorax, pulmonary complications and anastomotic fistula (P0.05), and the difference of 5 year survival rates between the two groups was different. There was no statistical significance (P=0.60). Conclusion: the long-term effect of the two kinds of surgical procedures was equal. The Sweet operation was more convenient than the Ivor-Lewis operation, saved the operation time and the patient was well tolerated; the Ivor-Lewis operation was able to clear more lymph nodes and no postoperative complications than the Sweet operation.

【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2015
【分類號】：R735.1

【參考文獻(xiàn)】

相關(guān)期刊論文 前1條

1 陳晟;;Ivor-Lewis手術(shù)治療食管癌的近期臨床療效與術(shù)后感染預(yù)防[J];中華醫(yī)院感染學(xué)雜志;2013年05期

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本文編號：1780006