肝癌邊緣假包膜與病理組織學(xué)分級(jí)相關(guān)性研究
發(fā)布時(shí)間:2018-04-17 18:27
本文選題:原發(fā)性肝癌 + 假包膜; 參考:《廣西醫(yī)科大學(xué)》2017年碩士論文
【摘要】:目的:研究肝細(xì)胞癌的邊緣假包膜特點(diǎn)對(duì)其病理組織學(xué)分級(jí)的診斷價(jià)值。方法:分析自2013年6月至2014年12月在廣西醫(yī)科大學(xué)第一附屬醫(yī)院經(jīng)手術(shù)或活檢病理證實(shí)為肝細(xì)胞癌,且病理診斷中包含腫瘤病理組織學(xué)分級(jí)的564例病人的影像資料,其中男性484例,女性80例,年齡范圍18-80歲,平均年齡49歲。通過觀察肝細(xì)胞癌CT、MRI出現(xiàn)邊緣假包膜的影像表現(xiàn),包括邊緣假包膜有無、是否完整以及假包膜在多期掃描圖像上強(qiáng)化最明顯時(shí)相等多項(xiàng)指標(biāo),分析肝癌假包膜與其病理組織學(xué)分型的關(guān)系。統(tǒng)計(jì)學(xué)的分析以及處理采用SPSS22.0統(tǒng)計(jì)軟件。結(jié)果:本研究CT和MRI檢出肝癌邊緣假包膜的差異有統(tǒng)計(jì)學(xué)意義(P0.05);小肝癌(直徑≤3cm),結(jié)節(jié)型肝癌(3cm,≤5cm),巨塊型肝癌(5cm)組之間病灶邊緣假包膜的有無、是否完整的差異有統(tǒng)計(jì)學(xué)意義(P0.05);肝癌的病理分化Ⅰ型(高分化肝癌、高-中分化肝癌)、Ⅱ型(中分化肝癌、中-低分化肝癌)、Ⅲ型(低、低-未分化、未分化肝癌)組之間,病灶邊緣假包膜完整率的差異有統(tǒng)計(jì)學(xué)意義(P0.05);不同病理分化程度的肝癌假包膜強(qiáng)化最明顯的時(shí)相,在動(dòng)脈期與門脈期強(qiáng)化最明顯、動(dòng)脈期與平衡期強(qiáng)化最明顯的分布差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論:肝癌CT和MRI假包膜檢出率比較,MRI優(yōu)于CT;肝癌病灶越大,邊緣假包膜檢出率越高,且假包膜表現(xiàn)為越不完整;假包膜完整率越低,肝癌病理分化程度越低;假包膜在動(dòng)脈期強(qiáng)化最明顯,提示肝癌病理分化程度越低。
[Abstract]:Objective: to study the diagnostic value of marginal pseudocapsule characteristics in hepatocellular carcinoma (HCC).Methods: from June 2013 to December 2014, the imaging data of 564 patients with hepatocellular carcinoma confirmed by operation or biopsy pathology in the first affiliated Hospital of Guangxi Medical University were analyzed.There were 484 males and 80 females, aged 18-80 years, with an average age of 49 years.The imaging features of marginal pseudocapsule in CT MRI of hepatocellular carcinoma (HCC) were observed, including whether or not the marginal pseudocapsule was present, whether the pseudocapsule was intact, and when the pseudocapsule was enhanced most obviously on the multiphase scanning images.To analyze the relationship between pseudocapsule and histopathological classification of liver cancer.Statistical analysis and processing using SPSS22.0 statistical software.Results: in this study, the difference between CT and MRI in detecting the marginal pseudocapsule of HCC was statistically significant (P 0.05), and in the small hepatocellular carcinoma (diameter 鈮,
本文編號(hào):1764754
本文鏈接:http://sikaile.net/yixuelunwen/zlx/1764754.html
最近更新
教材專著