本文選題：穿刺活檢 + 活檢針　； 參考：《山東大學(xué)》2016年碩士論文

【摘要】：穿刺活檢是基于活檢針來(lái)獲取所需的人體軟組織樣本,并利用電鏡病理細(xì)胞學(xué)檢測(cè)來(lái)診斷病癥的一種方法�；顧z針作為穿刺活檢中的基本工具,其幾何結(jié)構(gòu)對(duì)穿刺效率和精度有重大影響。目前臨床上使用的活檢針針尖切削刃幾何形狀比較單一,穿刺效率和精度都有待提高。當(dāng)前,活檢針的設(shè)計(jì)主要依賴(lài)設(shè)計(jì)者的經(jīng)驗(yàn),往往受限于已存在的活檢針,很難突破已有結(jié)構(gòu)設(shè)計(jì)出穿刺效率和精度高的活檢針。針對(duì)這種問(wèn)題,本文開(kāi)發(fā)了活檢針自動(dòng)參數(shù)化設(shè)計(jì)以及優(yōu)化集成系統(tǒng),實(shí)現(xiàn)了活檢針的自動(dòng)化、參數(shù)化、系統(tǒng)化設(shè)計(jì)與開(kāi)發(fā),避免了活檢針模型創(chuàng)建過(guò)程中的重復(fù)勞動(dòng),提高了活檢針設(shè)計(jì)以及開(kāi)發(fā)的效率。本課題的主要工作如下：活檢針針尖切削刃幾何結(jié)構(gòu)建模�；陬�(lèi)比的方式,穿刺活檢中活檢針刺入軟組織可以看成是金屬刀具切削材料,其中活檢針類(lèi)似金屬刀具是穿刺活檢的基礎(chǔ)器械�；诮饘偾邢鞯毒叩姆治龇椒�,建立活檢針的幾何結(jié)構(gòu)模型,并分別計(jì)算活檢針針尖切削刃的前角和刃傾角,為不同活檢針切削性能的簡(jiǎn)單判定提供依據(jù)�；赑ro/Toolkit開(kāi)發(fā)復(fù)雜曲面活檢針參數(shù)化設(shè)計(jì)系統(tǒng)。針對(duì)ABAQUS中無(wú)法精確創(chuàng)建曲面模型,本文基于Pro/Toolkit對(duì)Pro/E進(jìn)行二次開(kāi)發(fā),建立復(fù)雜曲面活檢針參數(shù)化設(shè)計(jì)系統(tǒng)。詳細(xì)介紹了Pro/Toolkit中二次開(kāi)發(fā)的關(guān)鍵技術(shù)以及復(fù)雜曲面活檢針參數(shù)化設(shè)計(jì)系統(tǒng)的應(yīng)用程序設(shè)計(jì)過(guò)程。復(fù)雜曲面活檢針參數(shù)化設(shè)計(jì)系統(tǒng)的設(shè)計(jì)對(duì)象的參數(shù)化驅(qū)動(dòng)。為了避免設(shè)計(jì)人員在復(fù)雜曲面針模型創(chuàng)建過(guò)程中的重復(fù)勞動(dòng),本文基于Pro/Toolkit零件參數(shù)化,運(yùn)用三維模型與程序控制相結(jié)合的方法,實(shí)現(xiàn)了復(fù)雜曲面針參數(shù)化設(shè)計(jì)系統(tǒng)的參數(shù)化設(shè)計(jì)�；顧z針自動(dòng)參數(shù)化設(shè)計(jì)與優(yōu)化集成系統(tǒng)開(kāi)發(fā)�；贏BAQUS二次開(kāi)發(fā)中的自定制應(yīng)用程序開(kāi)發(fā)了活檢針自動(dòng)參數(shù)化設(shè)計(jì)與優(yōu)化集成系統(tǒng),實(shí)現(xiàn)了簡(jiǎn)單平面針自動(dòng)參數(shù)化建模以及復(fù)雜曲面活檢針的模型導(dǎo)入。并基于MATLAB和Python的接口,實(shí)現(xiàn)了活檢針針尖切削刃上前角和刃傾角的自動(dòng)計(jì)算以及分布曲線圖的繪制,讓設(shè)計(jì)人員對(duì)設(shè)計(jì)與優(yōu)化的活檢針切削性能有了一個(gè)直觀的了解。
[Abstract]:Biopsy is a method based on biopsy needle to obtain the required human soft tissue samples and to use electron microscopic cytology to diagnose the disease.As a basic tool in biopsy, the geometric structure of biopsy needle has great influence on the efficiency and precision of puncture.At present, the cutting edge geometry of biopsy needle used in clinic is simple, and the puncture efficiency and precision need to be improved.At present, the design of biopsy needle mainly depends on the designer's experience, and is often limited by the existing biopsy needle, it is difficult to break through the existing structure to design the biopsy needle with high efficiency and precision.In order to solve this problem, the automatic parameterization design and optimization integrated system of biopsy needle are developed in this paper, which realizes the automation, parameterization, systematic design and development of biopsy needle, and avoids the repeated work in the process of creating biopsy needle model.The efficiency of design and development of biopsy needle is improved.The main work of this paper is as follows: modeling the geometric structure of needle tip cutting edge.Based on analogies, the biopsy needle can be regarded as the cutting material of metal cutting tool, in which the needle is similar to the metal tool and is the basic instrument of the puncture biopsy.Based on the analysis method of metal cutting tool, the geometric structure model of biopsy needle is established, and the anterior angle and edge dip angle of needle tip cutting edge are calculated respectively, which provides the basis for the simple judgment of cutting performance of different biopsy needle.A parameterized design system for complex curved needle biopsy was developed based on Pro/Toolkit.In view of the fact that the surface model can not be precisely created in ABAQUS, a parameterized design system for complex curved surface biopsy needle is established in this paper, which is based on the secondary development of Pro/E based on Pro/Toolkit.The key technology of secondary development in Pro/Toolkit and the application program design process of parameterized design system for complex curved needle biopsy are introduced in detail.Parametric drive of parametric design system for complex curved biopsy needle.In order to avoid the repeated work of the designer in the process of creating the needle model of complex curved surface, based on the parameterization of Pro/Toolkit parts, the method of combining 3D model with program control is used in this paper.The parametric design of the needle parameterized design system for complex curved surface is realized.Development of automatic Parametric Design and Optimization system for biopsy Needle.An integrated system for automatic parameterization design and optimization of biopsy needle is developed based on the custom application program in the secondary development of ABAQUS. The automatic parameterized modeling of simple planar needle and the model import of biopsy needle with complex curved surface are realized.Based on the interface of MATLAB and Python, the automatic calculation of cutting edge angle and edge inclination angle and the drawing of distribution curve are realized, which makes the designer have a direct understanding of the design and optimization of the cutting performance of the needle.
【學(xué)位授予單位】：山東大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2016
【分類(lèi)號(hào)】：TP311.52;R730.4

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