本文選題：血管內(nèi)皮生長因子　切入點：受體　出處：《中國老年學雜志》2017年02期

【摘要】：正卵巢癌早期往往不易診斷,約75%是在卵巢癌晚期及發(fā)生轉(zhuǎn)移遍布腹膜、肝臟的實質(zhì)或胸膜后才被確診~(〔1〕)。盡管目前卵巢癌的治療手段有所提高,但卵巢癌Ⅲ、Ⅳ期患者總體5年生存率分別為36%和17%~(〔2〕)。血管內(nèi)皮生長因子(VEGF)為特異的內(nèi)皮細胞有絲分裂素,通過其特異性受體(VEGFR)介導,在卵巢癌的發(fā)生、發(fā)展中發(fā)揮了舉足輕重的作用,最終導致惡性腹水的產(chǎn)生。卵巢癌發(fā)生、發(fā)展機制分子水平的鑒定,為卵
[Abstract]:Early diagnosis of positive ovarian cancer is often difficult, about 75% of the ovarian cancer and metastasis occurred throughout the peritoneum, liver parenchyma or pleura was only diagnosed after the diagnosis.Although the current treatment of ovarian cancer has been improved, the overall 5-year survival rate of patients with stage 鈪，

本文編號：1720367