發(fā)布時(shí)間：2018-03-29 06:12

  本文選題：中醫(yī)五音療法　切入點(diǎn)：乳腺癌　出處：《南京中醫(yī)藥大學(xué)》2017年碩士論文

【摘要】：目的:本研究意在觀察五音療法對乳腺癌患者化療期應(yīng)激狀態(tài)的影響。探索非藥物療法對乳腺癌患者化療期應(yīng)激狀態(tài)的干預(yù)機(jī)制。方法:將乳腺癌患者化療的40例符合納入標(biāo)準(zhǔn)的患者分為兩組:治療組20例,在化療及基礎(chǔ)治療的同時(shí)戴耳機(jī)聽音樂,每日上、下午各一次,每次20min 2個(gè)療程(21天為1個(gè)療程);對照組20例,單純化療及基礎(chǔ)治療。上述兩組在第一次化療前及化療第2、4及下一個(gè)化療周期的前一天、化療第2、4天評價(jià)療效,比較兩組患者化療毒副作用、應(yīng)激狀態(tài)癥狀評分、生活質(zhì)量評估、心理評分、白細(xì)胞計(jì)數(shù)、血小板計(jì)數(shù)、一氧化氮、超氧化物歧化酶、細(xì)胞免疫。結(jié)果:實(shí)驗(yàn)結(jié)束后,實(shí)驗(yàn)組和對照組有效病例均為20例。結(jié)果如下:實(shí)驗(yàn)采用應(yīng)激狀態(tài)觀察表、一氧化氮(NO)和超氧化物歧化酶(SOD)的測定,對患者的應(yīng)激狀態(tài)進(jìn)行評估。結(jié)果顯示五音療法可以改善患者的氧化應(yīng)激狀態(tài)。惡心嘔吐標(biāo)準(zhǔn)評分、血常規(guī)和細(xì)胞免疫測定結(jié)果表明五音療法可以改善患者的惡心嘔吐癥狀,提高患者的免疫力,但是沒有改善患化療后出現(xiàn)的骨髓抑制。通過對患者生活質(zhì)量評分表、焦慮抑郁量表對患者的生活質(zhì)量和心理狀態(tài)進(jìn)行評估,結(jié)果表明五音療法可以改善患者的生活質(zhì)量和焦慮抑郁的不良情緒。結(jié)論:中醫(yī)五音療法可以通過改善乳腺癌患者的高氧化應(yīng)激水平,緩解惡心嘔吐癥狀和焦慮抑郁情緒,提高患者的免疫力,從而提高了患者化療耐受力,減輕了毒副反應(yīng)。
[Abstract]:Objective: to observe the effect of five tone therapy on stress state of breast cancer patients during chemotherapy. To explore the intervention mechanism of non-drug therapy on stress state of breast cancer patients during chemotherapy. Patients who met the inclusion criteria were divided into two groups: the treatment group (20 cases), Listening to music with headphones while chemotherapy and basic therapy, once a day, once in the afternoon, 2 courses of 20min for 21 days as a course of treatment, 20 cases in the control group, 20 cases in the control group, 20 cases in the control group, 20 cases in the control group, Before the first chemotherapy and the day before the 2nd and the next chemotherapy cycle, the curative effect was evaluated on the 2nd day of chemotherapy and the 4th day after chemotherapy. The side effects of chemotherapy and the score of stress state symptom were compared between the two groups. Quality of life assessment, psychological score, white blood cell count, platelet count, nitric oxide, superoxide dismutase, cellular immunity. Results: after the experiment, There were 20 effective cases in the experimental group and the control group. The results were as follows: the stress state observation table, nitric oxide (no) and superoxide dismutase (SOD) were used in the experiment. The results showed that the five tone therapy could improve the oxidative stress state of the patients. The scores of nausea and vomiting standard, blood routine and cellular immunoassay showed that the five tone therapy could improve the nausea and vomiting symptoms of the patients. To improve the immunity of patients, but not to improve the bone marrow suppression after chemotherapy. The quality of life and mental state of patients were evaluated by rating scale of quality of life and anxiety and depression scale. The results show that five tone therapy can improve the quality of life and anxiety and depression of patients. Conclusion: traditional Chinese medicine can improve the high level of oxidative stress in patients with breast cancer, relieve nausea and vomiting symptoms and anxiety and depression. Improve the patient's immunity, thus improve the patient's tolerance to chemotherapy, reduce the toxic side effects.
【學(xué)位授予單位】：南京中醫(yī)藥大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2017
【分類號】：R737.9

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