本文選題：卵巢癌　切入點(diǎn)：乳腺癌　出處：《山西醫(yī)科大學(xué)》2015年碩士論文　論文類型：學(xué)位論文

【摘要】：目的:探討與婦科卵巢惡性腫瘤相關(guān)的卵巢乳腺雙原發(fā)癌的臨床特點(diǎn)。方法:搜集自2000年1月至2014年12月間由山西省腫瘤醫(yī)院收治的42例卵巢乳腺雙原發(fā)癌患者的臨床病例及組織病理資料進(jìn)行回顧性分析。結(jié)果:42例卵巢乳腺雙原發(fā)癌患者中,第一原發(fā)癌為乳腺癌的患者共36例。該部分患者患乳腺癌后的中位生存期為247個(gè)月,1、2、5年生存率分別為83.3%(35/42)、78.6%(33/42)和66.7%(28/42);患卵巢癌后的中位生存期46個(gè)月,1、2、5年生存率分別為73.8%(31/42)、64.3%(27/42)和14.3%(6/42)。4例第一原發(fā)癌是卵巢癌的患者生存時(shí)間為42-163個(gè)月,目前仍有3位患者存活,但其中2位患者的生存時(shí)間遠(yuǎn)遠(yuǎn)小于60個(gè)月。4例有乳腺癌家族史或卵巢癌家族史的雙原發(fā)癌患者,第二癌術(shù)后的5年生存率4.8%(2/42)。無惡性腫瘤家族史的33例雙原發(fā)癌患者中,第二癌術(shù)后1、2、5年生存率分別為35.7%(15/42)、21.4%(9/42)、和11.9%(5/42)。結(jié)論:1.病理分期、分化程度等情況是影響卵巢乳腺雙原發(fā)癌患者預(yù)后的重要因素,與首發(fā)卵巢癌患者相比,首發(fā)癌為乳腺癌的患者其生存期較長(zhǎng)。2.有卵巢癌、乳腺癌家族史和/或既往史的人群患卵巢乳腺雙原發(fā)癌的風(fēng)險(xiǎn)更高。3.對(duì)有高危因素的人群行遺傳基因檢測(cè),做好篩查隨訪工作,做到早發(fā)現(xiàn)、早診斷、早治療,避免誤診、漏診。
[Abstract]:Objective: to investigate the clinical features of double primary ovarian carcinoma associated with gynecological ovarian malignant tumor. Methods: 42 cases of ovarian double primary carcinoma of mammary gland were collected from January 2000 to December 2014 in Shanxi Cancer Hospital. The clinical and histopathological data were retrospectively analyzed. Results among 42 patients with ovarian and breast double primary carcinoma, There were 36 patients with primary breast cancer. The median survival time after breast cancer was 247 months, and the 5-year survival rate was 83.335 / 42 / 33 / 42 and 66.7 / 2842 / 42, respectively. The median survival time of ovarian cancer was 46 months / 12, and the 5-year survival rate was 73.38 / 42 / 44.32 / 2742 respectively. And 14.3R / 42.4 patients with primary ovarian cancer had a survival time of 42 to 163 months. Three patients are still alive, but two of them have a survival time of well under 60 months. 4 patients with a family history of breast or ovarian cancer have a history of double primary cancer. The 5-year survival rate of the second cancer patients was 4.8 / 42. In 33 patients with double primary cancer without a family history of malignant tumor, the survival rates for 1 and 5 years after operation for the second cancer were 35.710 / 42or 21.40.The survival rates were 9 / 42C and 11.9b / 42.Conclusion: 1, pathological stage, The degree of differentiation is an important factor that affects the prognosis of patients with double primary ovarian cancer. Compared with the patients with primary ovarian cancer, the patients with breast cancer in the first episode have a longer survival period of .2.The patients with ovarian cancer have ovarian cancer. The population with family history and / or previous history of breast cancer had a higher risk of developing double primary ovarian cancer. 3. Genetic detection was carried out in the population with high risk factors, screening and follow-up work was done, early detection, early diagnosis, early treatment, and avoiding misdiagnosis. Missed diagnosis
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類號(hào)】：R737.31

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 黃昶;賁門及肺雙原發(fā)癌1例[J];中國腫瘤臨床;2002年06期

2 任輝,王萍,李萱;胃、肺雙原發(fā)癌1例[J];中國腫瘤臨床與康復(fù);2002年06期

3 賀清波,丁潔,薛延軍,張曉榮,王霞云;雙原發(fā)癌臨床病理分析[J];現(xiàn)代腫瘤醫(yī)學(xué);2003年02期

4 叢龍松,姜宏志;胃雙原發(fā)癌一例[J];中國全科醫(yī)學(xué);2004年15期

5 高馨;;雙原發(fā)癌17例臨床分析[J];安徽衛(wèi)生職業(yè)技術(shù)學(xué)院學(xué)報(bào);2006年06期

6 譚小浪;安東建;;雙原發(fā)癌36例臨床分析[J];中國現(xiàn)代醫(yī)學(xué)雜志;2012年05期

7 王仁裕;;雙原發(fā)癌(附一例報(bào)告)[J];新疆醫(yī)學(xué)院學(xué)報(bào);1984年04期

8 許齊,鮑繼桂;早期消化道雙原發(fā)癌1例[J];腫瘤;1996年05期

9 郝俊芳,孫會(huì)英,孫玉華,孔凡英;雙原發(fā)癌10例報(bào)告[J];實(shí)用癌癥雜志;1998年02期

10 肖連波,趙海華;胃雙原發(fā)癌一例報(bào)告[J];胃腸病學(xué)和肝病學(xué)雜志;1999年03期

相關(guān)碩士學(xué)位論文 前2條

1 石婷;卵巢乳腺雙原發(fā)癌42例臨床分析[D];山西醫(yī)科大學(xué);2015年

2 李永麗;食管癌、胃癌及其雙原發(fā)癌組織CDH1基因啟動(dòng)子區(qū)CpG島甲基化的初步研究[D];河北醫(yī)科大學(xué);2010年

，

本文編號(hào)：1630592