本文選題：宮頸癌　切入點(diǎn)：卵巢癌　出處：《中華醫(yī)院感染學(xué)雜志》2017年17期 　論文類(lèi)型：期刊論文

【摘要】：目的探究在婦科惡性腫瘤患者中,宮頸癌和卵巢癌與梅毒螺旋體感染的相關(guān)性。方法選取2013年2月-2016年8月醫(yī)院婦科住院治療的宮頸癌患者269例和卵巢癌患者106例為研究對(duì)象,并選取1 000例普通患者作為對(duì)照,對(duì)宮頸癌組、卵巢癌組和普通患者組進(jìn)行梅毒螺旋體感染檢查,比較三組患者梅毒螺旋體感染率,對(duì)宮頸癌和卵巢癌患者按照術(shù)后病理學(xué)診斷進(jìn)行分型,比較各主要類(lèi)型患者的梅毒螺旋體感染率;比較宮頸癌組患者不同分期、不同年齡段、不同學(xué)歷區(qū)間的梅毒螺旋體感染率。結(jié)果宮頸癌組患者感染梅毒螺旋體31例,感染率為11.5%,卵巢癌組患者感染梅毒螺旋體4例,感染率為3.8%,普通患者組感染梅毒螺旋體34例,感染率為3.4%,宮頸癌組與普通患者組梅毒螺旋體感染率比較差異有統(tǒng)計(jì)學(xué)意義(P0.05),而卵巢癌組與普通患者組梅毒螺旋體感染率比較差異無(wú)統(tǒng)計(jì)學(xué)意義;宮頸鱗狀細(xì)胞癌患者感染率為12.6%,宮頸腺癌患者感染率為3.2%,腺鱗癌患者感染率為0,宮頸鱗狀細(xì)胞癌患者梅毒螺旋體感染率與其他宮頸癌病理分型比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05),漿液性囊腺癌患者感染率為4.1%,黏液性囊腺癌患者感染率為2.8%,子宮內(nèi)膜樣癌患者感染率為4.8%,卵巢癌3種病理分型患者梅毒螺旋體感染率比較差異無(wú)統(tǒng)計(jì)學(xué)意義;宮頸癌Ⅰ期患者感染率為16.2%,宮頸癌Ⅱ期患者感染率為6.3%,宮頸癌組不同分期感染率比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);30~39歲區(qū)間梅毒螺旋體感染率為18.5%,40~49歲區(qū)間感染率為24.6%,50~59歲區(qū)間感染率為5.6%,60歲區(qū)間感染率為2.0%,宮頸癌組不同年齡區(qū)間的感染率比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05);高中學(xué)歷以下患者感染率為16.2%,高中學(xué)歷及以上患者感染率為5.8%,宮頸癌組不同學(xué)歷區(qū)間的感染率比較,差異有統(tǒng)計(jì)學(xué)意義(P0.05)。結(jié)論宮頸癌患者有更大可能性感染梅毒螺旋體,卵巢癌患者與感染梅毒螺旋體無(wú)明顯關(guān)系,且宮頸癌患者感染梅毒螺旋體與病理分型、病理分期、年齡和學(xué)歷有關(guān)。
[Abstract]:Objective to investigate the correlation between cervical cancer and ovarian cancer and syphilis Treponema pallidum infection in gynecological malignant tumor patients. Methods 269 patients with cervical cancer and 106 patients with ovarian cancer who were hospitalized in gynecology from February 2013 to August 2016 were selected as subjects. The infection rate of Treponema pallidum in cervical cancer group, ovarian cancer group and general patient group was compared with that of cervical cancer group, ovarian cancer group and normal patient group. The patients with cervical cancer and ovarian cancer were classified according to postoperative pathological diagnosis to compare the infection rate of Treponema pallidum in each major type of patients, and different stages and ages of patients with cervical cancer were compared. Results there were 31 cases of Treponema pallidum infection in cervical cancer group, 4 cases in ovarian cancer group, and 3.8% in ovarian cancer group, and 34 cases were infected with Treponema pallidum in normal group. The infection rate of Treponema pallidum in cervical cancer group and normal patient group was 3.4. there was a significant difference in the infection rate of Treponema pallidum between cervical cancer group and normal patient group, but there was no significant difference between ovarian cancer group and normal patient group. The infection rate of cervical squamous cell carcinoma, adenocarcinoma and adenosquamous carcinoma was 12.6, 3.2 and 0 respectively. The infection rate of Treponema pallidum in patients with squamous cell carcinoma of cervix was higher than that in other cervical cancer. The infection rate of serous cystadenocarcinoma was 4.1, that of mucinous cystadenocarcinoma was 2.8, that of endometrioid carcinoma was 4.8. The infection rate of Treponema pallidum was lower in three types of ovarian cancer. There was no statistical significance. The infection rate of patients with stage I cervical cancer was 16.2and the infection rate of patients with stage 鈪，

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