發(fā)布時間：2018-02-26 07:41

  本文關(guān)鍵詞： 垂體腺瘤 經(jīng)鼻蝶手術(shù) 嗅覺 神經(jīng)內(nèi)鏡 顯微鏡　出處：《臨床耳鼻咽喉頭頸外科雜志》2017年19期 　論文類型：期刊論文

【摘要】：目的:探討顯微鏡下經(jīng)鼻蝶竇入路(MTS)及神經(jīng)內(nèi)鏡技術(shù)(ETS)下經(jīng)鼻蝶入路術(shù)后出現(xiàn)嗅覺功能障礙的相關(guān)因素,以進(jìn)一步指導(dǎo)臨床診治。方法:在回顧性研究中,對入組患者進(jìn)行病例資料分析,并進(jìn)行電話隨訪,記錄術(shù)前術(shù)后嗅覺情況;利用五味試嗅液檢測方法對前瞻性研究中的入組患者進(jìn)行術(shù)前,術(shù)后1周、1個月、3個月、6個月檢查,將結(jié)果進(jìn)行統(tǒng)計學(xué)分析。結(jié)果:回顧性研究中,MTS組、ETS組患者術(shù)后嗅覺障礙發(fā)生率分別為67.74%和47.37%,差異無統(tǒng)計學(xué)意義(P0.05),對可能的相關(guān)因素進(jìn)行統(tǒng)計學(xué)分析,結(jié)果顯示差異均無統(tǒng)計學(xué)意義。前瞻性研究中,ETS和MTS組術(shù)側(cè)鼻腔、非術(shù)側(cè)鼻腔的術(shù)前及術(shù)后結(jié)果之間、術(shù)后3次結(jié)果之間差異均有統(tǒng)計學(xué)意義(P0.05);4次檢查結(jié)果中,ETS組和MTS組患者各自術(shù)側(cè)鼻腔與非術(shù)側(cè)比較,差異無統(tǒng)計學(xué)意義(P0.05)。結(jié)論:經(jīng)鼻蝶手術(shù)入路切除垂體瘤術(shù)后會出現(xiàn)嗅覺功能障礙,積極做好術(shù)前鼻腔準(zhǔn)備,術(shù)中盡可能保護(hù)鼻腔結(jié)構(gòu)完整,術(shù)后給予適當(dāng)處理,可能會降低嗅覺障礙發(fā)生率。
[Abstract]:Objective: to investigate the related factors of olfactory dysfunction after transsphenoidal approach (MTS) under microscope and endoscopic approach (ETS) in order to guide the clinical diagnosis and treatment. Case data were analyzed and telephone follow-up was conducted to record the olfactory status before and after operation, and the patients in prospective study were examined before operation, 1 week, 1 month, 3 months and 6 months after operation by using the method of five flavor test olfactory fluid detection, and the results were as follows: 1 week, 1 month, 3 months and 6 months after operation. Results: the incidence of postoperative olfactory disorders in MTS group was 67.74% and 47.37, respectively. There was no significant difference (P 0.05). The possible related factors were analyzed statistically. The results showed that there was no significant difference between the preoperative and postoperative results of the two groups in prospective study. There were significant differences among the three postoperative results (P 0.05). The nasal cavity of the patients in the MTS group and the MTS group were compared with those in the non-operative side. Conclusion: after transsphenoidal resection of pituitary adenoma, olfactory dysfunction will occur, the nasal cavity should be prepared before operation, the structure of nasal cavity should be protected as much as possible, and the proper treatment should be given after operation. May reduce the incidence of olfactory disorders.
【作者單位】： 寧夏醫(yī)科大學(xué)總醫(yī)院神經(jīng)外科;寧夏醫(yī)科大學(xué)總醫(yī)院肝膽外科;山東省冠縣中心醫(yī)院腦電圖室;邢臺市人民醫(yī)院神經(jīng)外科;
【分類號】：R736.4
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本文編號：1537143