發(fā)布時間：2018-02-25 00:16

  本文關(guān)鍵詞： 宮頸上皮內(nèi)瘤變 滴蟲 沙眼衣原體 解脲脲原體 人乳頭瘤病毒　出處：《中華醫(yī)院感染學(xué)雜志》2017年12期 　論文類型：期刊論文

【摘要】：目的探討宮頸上皮內(nèi)瘤變(CIN)與生殖道滴蟲、細菌性陰道病、沙眼衣原體、解脲脲原體、人乳頭瘤病毒(HPV)感染的關(guān)系。方法選擇醫(yī)院婦科2014年1月-2015年12月宮頸CIN患者300例為CIN組,宮頸上皮正常者300例為對照組,檢測生殖道滴蟲、細菌性陰道病、沙眼衣原體、解脲脲原體、HPV感染情況。結(jié)果 CIN組滴蟲、細菌性陰道病、沙眼衣原體、解脲脲原體、HPV16/18感染率(25.3%、29.3%、29.0%、53.0%、75.0%)均高于對照組(13.0%、14.7%、7.3%、43.7%、4.0%)(P0.05);CINⅠ亞組、CINⅡ亞組、CINⅢ亞組之間生殖道滴蟲、細菌性陰道病、沙眼衣原體、解脲脲原體感染率比較差異無統(tǒng)計學(xué)意義,CINⅡ亞組、CINⅢ亞組HPV16/18感染率(83.5%、92.4%)均明顯高于CINⅠ亞組(55.9%),但CINⅡ亞組和CINⅢ亞組HPV16/18感染率比較差異無統(tǒng)計學(xué)意義;CIN組HPV16/18感染合并滴蟲感染、HPV16/18感染合并細菌性陰道病、HPV16/18感染合并沙眼衣原體、HPV16/18感染合并解脲脲原體的發(fā)生率(6.7%、11.7%、18.0%、40.3%)均高于對照組(0.3%、0.3%、1.0%、1.7%)(P0.05);生殖道HPV16/18感染與滴蟲、細菌性陰道病、沙眼衣原體感染呈正相關(guān)(r=0.013、0.020、0.027,P0.05),和解脲脲原體感染無顯著相關(guān)性。結(jié)論宮頸CIN與生殖道滴蟲、細菌性陰道病、沙眼衣原體、解脲脲原體、HPV16/18感染有關(guān),HPV16/18感染與病情進展有關(guān),與生殖道滴蟲、細菌性陰道病、沙眼衣原體感染呈正相關(guān)。
[Abstract]:Objective to investigate the relationship between cervical intraepithelial neoplasia (cin) and genital trichomonas, bacterial vaginosis, chlamydia trachomatis, Ureaplasma Urealyticum. Methods three hundred patients with cervical CIN from January 2014 to December 2015 were selected as CIN group and 300 normal cervix epithelium as control group. Trichomonad, bacterial vaginosis and chlamydia trachomatis were detected. Results the infection rates of trichomonad, bacterial vaginosis, chlamydia trachomatis and HPV16 / 18 in CIN group were higher than those in the control group. Chlamydia trachomatis, There was no significant difference in Ureaplasma Urealyticum infection rate. The HPV16/18 infection rate in cin 鈪，

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