本文關(guān)鍵詞： 腎上腺醛固酮瘤 腹腔鏡腎上腺部分切除術(shù) 腹腔鏡腎上腺全切除術(shù) Meta分析 偏倚　出處：《河北醫(yī)科大學(xué)》2015年碩士論文　論文類(lèi)型：學(xué)位論文

【摘要】：目的:比較腹腔鏡腎上腺全切術(shù)(laparoscopic total adrenalectomy,LA)與部分切除術(shù)(laparoscopic partial adrenalectomy,LPA)治療腎上腺醛固酮瘤(aldosterone-producing adenomas,APA)的療效。方法:應(yīng)用計(jì)算機(jī)檢索1988-01至2014-05期間Pubmed,Dspace,Social Science Research Network,CNKI,萬(wàn)方數(shù)據(jù)庫(kù)。納入涉及腹腔鏡單側(cè)腎上腺全切術(shù)與部分切除術(shù)治療腎上腺醛固酮瘤有效性及安全性的研究。依據(jù)Cochrane手冊(cè)對(duì)所有納入研究進(jìn)行質(zhì)量評(píng)價(jià)并應(yīng)用Stata11軟件進(jìn)行Meta分析。結(jié)果:共納入7個(gè)研究,包括914例患者,腹腔鏡單側(cè)腎上腺部分切除術(shù)組共511例,腹腔鏡單側(cè)腎上腺全切術(shù)組共403例。所有7篇研究進(jìn)行Meta分析,結(jié)果顯示LPA組與LA組手術(shù)時(shí)間差異無(wú)統(tǒng)計(jì)學(xué)意義[WMD=2.436,95%CI(-4.834,9.706),P0.05];LPA組與LA組出血量差異無(wú)統(tǒng)計(jì)學(xué)意義[WMD=3.225,95%CI(-5.654,12.103),P0.05];LPA組與LA組手術(shù)后引流管拔除時(shí)間差異無(wú)統(tǒng)計(jì)學(xué)意義[Z=0.40,95%CI(-0.299,0.198),P0.05];LPA組與LA組住院天數(shù)差異無(wú)統(tǒng)計(jì)學(xué)意義[Z=0.33,95%CI(-0.325,0.230),P0.05]。結(jié)論:針對(duì)腎上腺醛固酮瘤的手術(shù)治療,腹腔鏡腎上腺全切術(shù)與部分切除術(shù)在手術(shù)時(shí)間、術(shù)中出血量、術(shù)后傷口引流管拔除時(shí)間、住院時(shí)間上的差異均無(wú)統(tǒng)計(jì)學(xué)意義。上述結(jié)論尚需高質(zhì)量、大樣本的隨機(jī)對(duì)照試驗(yàn)加以證實(shí)。
[Abstract]:Objective: to compare the efficacy of laparoscopic total adrenalectomy with partial partial in the treatment of adrenal aldosterone-producing adenomatosis (APA). Methods: a computer-based search of PubmedDspacespace Social Science Research Network CNKI was performed from January 1988 to May 2014-05, which was included in the database of adrenal aldosterone-producing adrenal aldosterone. Study on the efficacy and safety of laparoscopic unilateral total adrenalectomy and partial resection in the treatment of adrenal aldosteronoma. All included studies were evaluated according to the Cochrane manual and Meta analysis was performed using Stata11 software. A total of seven studies were included, There were 511 cases in laparoscopic partial adrenalectomy group and 403 cases in laparoscopic total adrenalectomy group. All 7 studies were analyzed by Meta. The results showed that there was no significant difference in the operation time between LPA group and LA group [WMD-4.834-9.706] there was no significant difference in the bleeding volume between LPA group and LA group [WMD3.225 95CIM-5.654 + 12.103] there was no significant difference between LPA group and LA group in the extubation time after operation. There was no significant difference in the difference between the two groups. Conclusion: the surgical treatment of adrenal aldosteronoma was performed on adrenal aldosterone tumor. There was no significant difference between total laparoscopic adrenalectomy and partial adrenalectomy in operative time, blood loss during operation, extubation time of wound drainage tube after operation and hospitalization time. Large samples of randomized controlled trials were confirmed.
【學(xué)位授予單位】：河北醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2015
【分類(lèi)號(hào)】：R736.6

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本文編號(hào)：1518027