本文關鍵詞： 腎上腺醛固酮瘤 腹腔鏡腎上腺部分切除術 腹腔鏡腎上腺全切除術 Meta分析 偏倚　出處：《河北醫(yī)科大學》2015年碩士論文　論文類型：學位論文

【摘要】：目的:比較腹腔鏡腎上腺全切術(laparoscopic total adrenalectomy,LA)與部分切除術(laparoscopic partial adrenalectomy,LPA)治療腎上腺醛固酮瘤(aldosterone-producing adenomas,APA)的療效。方法:應用計算機檢索1988-01至2014-05期間Pubmed,Dspace,Social Science Research Network,CNKI,萬方數(shù)據(jù)庫。納入涉及腹腔鏡單側腎上腺全切術與部分切除術治療腎上腺醛固酮瘤有效性及安全性的研究。依據(jù)Cochrane手冊對所有納入研究進行質量評價并應用Stata11軟件進行Meta分析。結果:共納入7個研究,包括914例患者,腹腔鏡單側腎上腺部分切除術組共511例,腹腔鏡單側腎上腺全切術組共403例。所有7篇研究進行Meta分析,結果顯示LPA組與LA組手術時間差異無統(tǒng)計學意義[WMD=2.436,95%CI(-4.834,9.706),P0.05];LPA組與LA組出血量差異無統(tǒng)計學意義[WMD=3.225,95%CI(-5.654,12.103),P0.05];LPA組與LA組手術后引流管拔除時間差異無統(tǒng)計學意義[Z=0.40,95%CI(-0.299,0.198),P0.05];LPA組與LA組住院天數(shù)差異無統(tǒng)計學意義[Z=0.33,95%CI(-0.325,0.230),P0.05]。結論:針對腎上腺醛固酮瘤的手術治療,腹腔鏡腎上腺全切術與部分切除術在手術時間、術中出血量、術后傷口引流管拔除時間、住院時間上的差異均無統(tǒng)計學意義。上述結論尚需高質量、大樣本的隨機對照試驗加以證實。
[Abstract]:Objective: to compare the efficacy of laparoscopic total adrenalectomy with partial partial in the treatment of adrenal aldosterone-producing adenomatosis (APA). Methods: a computer-based search of PubmedDspacespace Social Science Research Network CNKI was performed from January 1988 to May 2014-05, which was included in the database of adrenal aldosterone-producing adrenal aldosterone. Study on the efficacy and safety of laparoscopic unilateral total adrenalectomy and partial resection in the treatment of adrenal aldosteronoma. All included studies were evaluated according to the Cochrane manual and Meta analysis was performed using Stata11 software. A total of seven studies were included, There were 511 cases in laparoscopic partial adrenalectomy group and 403 cases in laparoscopic total adrenalectomy group. All 7 studies were analyzed by Meta. The results showed that there was no significant difference in the operation time between LPA group and LA group [WMD-4.834-9.706] there was no significant difference in the bleeding volume between LPA group and LA group [WMD3.225 95CIM-5.654 + 12.103] there was no significant difference between LPA group and LA group in the extubation time after operation. There was no significant difference in the difference between the two groups. Conclusion: the surgical treatment of adrenal aldosteronoma was performed on adrenal aldosterone tumor. There was no significant difference between total laparoscopic adrenalectomy and partial adrenalectomy in operative time, blood loss during operation, extubation time of wound drainage tube after operation and hospitalization time. Large samples of randomized controlled trials were confirmed.
【學位授予單位】：河北醫(yī)科大學
【學位級別】：碩士
【學位授予年份】：2015
【分類號】：R736.6

【參考文獻】

相關期刊論文 前4條

1 李國英;孫鋼;李勝輝;劉訓偉;奚剛;李海軍;;CT引導下經(jīng)皮穿刺化學消融治療腎上腺醛固酮瘤的臨床研究[J];實用放射學雜志;2007年02期

2 孫志熙，張健，劉燕云，，劉光偉，邱鳳芝;腎上腺腫瘤243例臨床分析[J];中國醫(yī)科大學學報;1996年03期

3 王亮;李黎明;林毅;;腹腔鏡行腎上腺部分切除術與全切術治療腎上腺原醛瘤的比較:附235例報告[J];中華腔鏡泌尿外科雜志(電子版);2012年02期

4 莫傳偉,陳群,徐志偉;Stata軟件在臨床試驗計量資料效應比較的Meta分析中的應用[J];中藥新藥與臨床藥理;2005年02期

相關碩士學位論文 前2條

1 李欽濤;影響腎上腺醛固酮瘤術后血壓變化的多因素分析[D];廣西醫(yī)科大學;2012年

2 蘇陳強;腹膜后腹腔鏡患側腎上腺全切術與部分切除術治療腎上腺醛固酮瘤的對比研究[D];福建醫(yī)科大學;2013年

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