本文關(guān)鍵詞： 胃癌 CA CA CA CEA 腫瘤標(biāo)志物　出處：《中國老年學(xué)雜志》2017年01期 　論文類型：期刊論文

【摘要】：目的觀察腫瘤標(biāo)志物CA724、CA199、CA242、CEA單項(xiàng)及聯(lián)合檢測在老年胃癌診斷中的價值。方法選取老年胃癌患者50例作為觀察組,同時選取慢性萎縮性胃炎伴重度不典型增生的患者50例為對照1組,選取淺表性胃炎或正常胃黏膜者50例作為對照2組。檢測三組觀察對象的血清,上午取空腹靜脈血10 ml,用離心機(jī)分離,然后將分離血清存貯在-90℃的冷凍冰箱進(jìn)行保存,最后進(jìn)行腫瘤標(biāo)志物CA724、CA199、CA242、CEA檢測。且通過CA724、CA199、CA242、CEA單項(xiàng)及聯(lián)合檢測分析不同分化程度和不同分級的檢測情況。結(jié)果觀察組患者血清腫瘤標(biāo)志物各項(xiàng)指標(biāo)明顯高于對照1組和對照2組(P0.05和P0.01);且對照1組各項(xiàng)指標(biāo)均明顯高于對照2組(P0.05)。高、中分化組胃癌患者CA724、CA199、CA242陽性率均優(yōu)于低分化組(P0.05)。各組CEA陽性率差異不明顯(P0.05)。Ⅰ和Ⅱ期胃癌患者4種腫瘤標(biāo)志物陽性水平明顯低于Ⅳ期(P0.05)。Ⅰ和Ⅱ期胃癌患者腫瘤標(biāo)志物陽性率明顯高于Ⅳ期(P0.05)。結(jié)論腫瘤標(biāo)志物CA724、CA199、CA242、CEA的水平異常升高或可提示有癌前病變或胃癌的發(fā)生,它可作為胃癌早期診斷的重要輔助指標(biāo)。
[Abstract]:Objective to observe the value of CA724 + CA1999 CA242CEA in the diagnosis of gastric cancer in the elderly. Methods 50 cases of senile gastric cancer were selected as observation group and 50 cases of chronic atrophic gastritis with severe atypical hyperplasia as control group 1. 50 patients with superficial gastritis or normal gastric mucosa were selected as control group. The serum samples of three groups were detected. Fasting venous blood was collected from 10 ml in the morning, separated by centrifuge, and then stored in a frozen refrigerator at -90 鈩，

本文編號：1505107