【摘要】：隨著人口平均壽命顯著延長，世界上許多國家與我國對老年醫(yī)學已極為重視。而抑郁癥是二十一世紀威脅人類健康的三大衛(wèi)生課題之一，聯(lián)合國世界衛(wèi)生組織針對全球性的疾病負擔估算，指出至二○二○年，抑郁癥將成為所有疾病中排名第二的高負擔與失能疾病。但是流行病學的調(diào)查研究顯示老年人抑郁癥狀的盛行率遠超過抑郁疾患的盛行率。所以本課題是研究包含老年抑郁癥在內(nèi)的老年抑郁狀態(tài)相關的流行病學研究；中醫(yī)對老年抑郁的認識、病因病機的探討、辨證分型與治療；西醫(yī)對老年抑郁的認識、病理變化的研究、診斷的標準、鑒別診斷與治療；以及中西醫(yī)結(jié)合治療老年抑郁的現(xiàn)況，而目前大都是以中藥或針刺配合較小劑量的西藥為研究較多，降低單用西藥的副作用以提高療效。此外，中西醫(yī)結(jié)合治療老年抑郁尚須解決的問題包括：辨證分型急待規(guī)范、有效治療藥物及方劑的篩選、重視不同證型之間重疊性的研究以及制定規(guī)范統(tǒng)一的療效標準。如此將有助于中西結(jié)合治療老年抑郁的實證式研究。 西醫(yī)對老年抑郁仍欠缺快速的篩檢檢測儀器，我們首次嘗試以計算機經(jīng)絡能量分析儀器MEAD，探討臨床上快速篩檢老年抑郁狀態(tài)的可行性。我們針對70位65歲以上的老人，，研究分析經(jīng)由老年抑郁量表(Geriatrics Depression Scale，GDS)評量與計算機經(jīng)絡能量分析儀器檢測結(jié)果彼此之間的相關性。結(jié)果顯示：GDS量表的評量分數(shù)與十二經(jīng)脈中的肝經(jīng)偏離平均值的變化程度有顯著的正相關(p＜0.01)；而與陰陽經(jīng)脈的導電量總合比值則是呈顯著的負相關(p＜0.05)。這結(jié)果與肝氣郁結(jié)是抑郁表現(xiàn)的主要病機，以及臟氣虛弱是老年抑郁的重要內(nèi)在發(fā)病因素相謀合。由本研究結(jié)果得知，計算機經(jīng)絡能量分析儀器有可能成為臨床上輔助快速篩選老年抑郁狀態(tài)的客觀檢查儀器。
[Abstract]:With the increase of life expectancy, many countries in the world and our country have attached great importance to geriatrics. And depression is one of the three major health issues that threaten human health in the 21 century. The United Nations World Health Organization (WHO) estimates the global burden of disease and points out that by the year 2020, Depression will be the second highest burden and disability of all diseases. But epidemiological studies show that the prevalence of depression in the elderly is much higher than the prevalence of depression. Therefore, this topic is to study the elderly depression including the elderly depression related epidemiological study, TCM understanding of the elderly depression, etiology and pathogenesis of the discussion, syndrome differentiation and treatment; Western medicine to the elderly depression understanding, pathological changes, diagnostic criteria, differential diagnosis and treatment; And the current situation of integrated traditional Chinese medicine and western medicine in the treatment of depression in the elderly, but at present, most of them have been studied by traditional Chinese medicine or acupuncture combined with small dose of western medicine, so as to reduce the side effects of single use of western medicine in order to improve the curative effect. In addition, the problems to be solved in the treatment of senile depression by combination of traditional Chinese and western medicine include the urgent standardization of syndrome differentiation and classification, the screening of effective drugs and prescriptions, the emphasis on overlapping studies among different syndrome types, and the formulation of standardized and unified therapeutic standards. This will contribute to the combination of Chinese and Western medicine in the treatment of senile depression empirical study. There is still no rapid screening instrument for senile depression in western medicine. We first tried to use the computer meridian energy analysis instrument MEAD, to explore the feasibility of rapid screening for senile depression in clinic. We studied and analyzed the correlation between the results of the Geriatric Depression scale (Geriatrics Depression Scale,GDS) and the results of computer meridian energy analysis in 70 elderly people over 65 years old. The results showed that there was a significant positive correlation between the score of the GDS scale and the mean deviation of the hepatic meridians in the twelve meridians (p < 0 01). There was a significant negative correlation between the total electric conductivity ratio of yin-yang meridian and Yin-Yang meridian (p < 0.05). These results are consistent with the main pathogenesis of depression, and the weakness of visceral qi is an important internal pathogenic factor of depression in the elderly. According to the results of this study, the computer meridian energy analysis instrument may be used as an objective examination instrument to assist in the rapid screening of depression in the elderly.
【學位授予單位】：南京中醫(yī)藥大學
【學位級別】：博士
【學位授予年份】：2004
【分類號】：R749.4

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相關期刊論文 前2條

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