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陰道微生態(tài)與中西醫(yī)結合治療陰道炎的臨床療效觀察

發(fā)布時間:2018-06-20 02:55

  本文選題:陰道微生態(tài) + 陰道炎; 參考:《云南中醫(yī)學院》2017年碩士論文


【摘要】:目的:陰道炎(Vaginitis)是最多見的女性生殖道感染性疾病,有較高的復發(fā)性。本文通過探討中西醫(yī)結合治療婦科常見陰道炎的療效,并對相關微生態(tài)進行評估,通過臨床試驗,為治療陰道炎尋找一種最佳的治療方法,為臨床用藥提供客觀實驗依據(jù)。方法:選取我院門診及住院診治的陰道炎患者600例,其中外陰陰道假絲酵母菌病300例,細菌性陰道病300例,每種疾病根據(jù)治療方法的不同分為中醫(yī)治療組、西醫(yī)治療組以及中西醫(yī)結合治療組,每組患者各100例。所選患者均進行7天一療程的治療,在治療前后對陰道分泌物染色標本結果評價---Nugent評分,并對陰道PH值、過氧化氫、白細胞酯酶、唾液酸苷酶的變化分析,進而對其進行微生態(tài)分析,采用統(tǒng)計學軟件SPSS19.0進行分析。結果:細菌性陰道病年齡分布結果可見22-31歲之間的患者最多占42%,其次為32-41歲之間占28%,再次為小于22歲的占24%。外陰陰道假絲酵母菌病患者300例,其年齡分布結構可見22-31歲之間的患者最多占40%,其次為32-41歲之間占32%,再次為小于22歲的患者占23%。細菌性陰道病患者300例,中醫(yī)證型分布結果顯示濕熱下注證患者最多占44%,脾虛濕盛證占40%,腎陽虛證占12%,溫毒蘊結證占4%。外陰陰道假絲酵母菌性陰道炎患者300例,中醫(yī)證型分布結果顯示患者濕熱下注證最多占46%,脾虛濕盛證占38%,腎陽虛證占11%,溫毒蘊結證占5%;治療后,細菌性陰道病患者、外陰陰道假絲酵母菌病患者的中西醫(yī)治療有效率明顯高于單純中醫(yī)、西醫(yī)治療組,差異有統(tǒng)計學意義(p0.05):而單純中醫(yī)治療與西醫(yī)治療組間比較有效率差異不顯著,無統(tǒng)計學意義(p0.05),PH值、過氧化氫、白細胞酯酶以及唾液酸苷酶治療前后相比較(p0.05),具有統(tǒng)計學意義。結論:三組治療方法治療細菌性陰道病、外陰陰道假絲酵母菌病具有一定的療效,其中西醫(yī)聯(lián)合中藥熏洗方治療效果最優(yōu)。
[Abstract]:Objective: Vaginitis is the most common infectious disease in female genital tract. This article discusses the curative effect of the treatment of gynecological common vaginitis with the combination of traditional Chinese and western medicine, and evaluates the related microecology. Through the clinical trial, we seek a kind of best treatment method for treating vaginitis, and provide the objective experimental basis for the clinical use of drugs. Methods: a total of 600 patients with vaginitis were selected, including 300 cases of vulvovaginal candidiasis and 300 cases of bacterial vaginosis. Western medicine treatment group and integrated Chinese and western medicine treatment group, each group of 100 patients. All the patients were treated for 7 days. The results of vaginal discharge staining were evaluated by -Nugent score before and after treatment, and the changes of PH value, hydrogen peroxide, leucocyte esterase and sialidase were analyzed. Then the microecological analysis was carried out and the statistical software SPSS 19.0 was used to analyze it. Results: the age distribution of bacterial vaginosis showed that 42 22 cases were aged 22 to 31 years old, 28 cases were between 32 and 41 years old, and 24 cases were younger than 22 years old. There were 300 cases of vulvovaginal candidiasis. The age distribution structure showed that 40 cases were between 22 and 31 years old, 32 cases were between 32 and 41 years old, and 23 cases were younger than 22 years old. There were 300 patients with bacterial vaginosis. The distribution of TCM syndromes showed that the most 44 cases were damp-heat betting syndrome, 40 cases were spleen deficiency dampness syndrome, 12 cases were kidney yang deficiency syndrome, and 4 cases were warm toxin accumulation syndrome. In 300 cases of vulvovaginal candida vaginitis, the distribution of TCM syndromes showed that the maximum number of patients with dampness and heat betting syndrome was 46, spleen deficiency dampness syndrome was 38, kidney yang deficiency syndrome was 11 and warm toxin accumulation syndrome was 50.After treatment, bacterial vaginosis patients, The effective rate of traditional Chinese medicine and western medicine in vulvovaginal Candida cerevitis patients was significantly higher than that in traditional Chinese medicine group and western medicine treatment group, the difference was statistically significant (p 0.05). However, there was no significant difference in effective rate between traditional Chinese medicine treatment group and western medicine treatment group. There was no significant difference in PH value between before and after treatment with hydrogen peroxide, leucocyte esterase and sialidase. Conclusion: three groups of treatment methods for bacterial vaginosis vulvovaginal candidiasis has a certain curative effect its traditional Chinese and Western medicine combined with Chinese medicine fumigation and washing prescription is the best.
【學位授予單位】:云南中醫(yī)學院
【學位級別】:碩士
【學位授予年份】:2017
【分類號】:R711.31

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