通過(guò)血管鑄型技術(shù)及CT三維重建來(lái)探討子宮血管分布及血管網(wǎng)的意義
發(fā)布時(shí)間：2019-05-21 22:13
【摘要】：目的： 通過(guò)對(duì)家兔的血管鑄型技術(shù)、方法的進(jìn)一步探討及研究，從而獲得家兔子宮動(dòng)脈血管鑄型標(biāo)本，以及通過(guò)對(duì)人子宮血管行CT三維重建獲得的影像資料，共同來(lái)觀察子宮動(dòng)脈、子宮動(dòng)脈-卵巢支、子宮動(dòng)脈-輸卵管支的分布情況，以及對(duì)子宮動(dòng)脈血管網(wǎng)的研究和分布情況，進(jìn)一步對(duì)子宮動(dòng)脈血管網(wǎng)吻合支的研究。 方法： 家兔正常麻醉處死后，于腹主動(dòng)脈進(jìn)行插管的同時(shí)行髂外動(dòng)脈絲線結(jié)扎，來(lái)對(duì)家兔子宮及雙側(cè)輸卵管、卵巢行血管鑄型。鑄型材料采用乙酸乙酯和過(guò)氯乙烯及鄰苯二甲酸二丁酯、部分油畫染料充分?jǐn)噭蚝笞鰹樘畛鋭�，在插管后再行補(bǔ)灌注、腐蝕、沖洗、標(biāo)本休整、標(biāo)本保存等步驟，來(lái)完成家兔子宮血管鑄型標(biāo)本的制備。人體子宮動(dòng)脈影像圖像可通過(guò)行靜脈血管打入血管造影劑，后經(jīng)CT三維重建獲得子宮動(dòng)脈血管圖像。 結(jié)果： 通過(guò)對(duì)家兔子宮鑄型標(biāo)本的觀察，可以清晰的觀察到子宮動(dòng)脈血管的分布情況，以及子宮血管的二、三級(jí)分支及分布情況，對(duì)于細(xì)小的血管網(wǎng)借助掃描電鏡可觀察到子宮動(dòng)脈卵巢支、輸卵管支的血管分布及血管網(wǎng)吻合支情況。主要表現(xiàn)為： 1通過(guò)血管鑄型獲得的子宮血管情況： (1)子宮動(dòng)脈血管網(wǎng)分布及吻合支分布情況： 1兔子宮動(dòng)脈于宮體兩側(cè)迂曲向上，于宮體部發(fā)出子宮動(dòng)脈螺旋支，雖較為細(xì)小，，但可通過(guò)放大鏡或者掃描電鏡觀察到子宮體部存在明顯的交通支，且分布十分密集，進(jìn)一步證明了子宮動(dòng)脈存在明顯的相互供血傾向。2子宮動(dòng)脈上行支為子宮體、卵巢和輸卵管供血,下行支由于取標(biāo)本原因未能顯示。3子宮動(dòng)脈上行支迂曲延輸卵管走形發(fā)出子宮動(dòng)脈卵巢支，可見(jiàn)子宮動(dòng)脈卵巢支與卵巢動(dòng)脈相互吻合情況。 2.通過(guò)對(duì)人靜脈血管打入造影劑，經(jīng)CT三維重建獲得的子宮動(dòng)脈血管圖像情況： (1)子宮動(dòng)脈血管分布情況： 1正常子宮動(dòng)脈主干于宮頸內(nèi)口水平依次分出膀胱支、輸尿管支、上行支和下行支等動(dòng)脈血管，可清晰看到子宮及其上行支，下行支、膀胱支及輸尿管支由于由于血管較細(xì)造影劑流入較少故未能顯示。2可觀察到較粗大的子宮動(dòng)脈上行支,沿子宮壁的側(cè)緣迂曲向上,沿途可見(jiàn)子宮動(dòng)脈上行支發(fā)出多條弓狀動(dòng)脈，弓狀動(dòng)脈再發(fā)出若干螺旋動(dòng)脈,分布于子宮前、后面,在到達(dá)子宮底水平后，在子宮角處發(fā)出多條分支，分別為宮底支、卵巢支和輸卵管支；子宮動(dòng)脈上行支主要為子宮體、卵巢和輸卵管供血。 (2)子宮動(dòng)脈血管網(wǎng)分布形及吻合支分布情況： 1子宮動(dòng)脈以中軸線為中心，可清晰看到兩側(cè)存在明顯的交通支，盡管較為微細(xì)，但分布較為集中且密集，進(jìn)一步證明了子宮動(dòng)脈存在明顯的相互供血傾向。2可見(jiàn)沿子宮壁迂曲向上的子宮動(dòng)脈上行支于子宮角處直接發(fā)出較粗大的卵巢支,經(jīng)過(guò)卵巢固有韌帶向卵巢提供部分供血，由此可見(jiàn)，卵巢的血供不單有卵巢動(dòng)脈供給，還有子宮動(dòng)脈卵巢支。 結(jié)論： 通過(guò)應(yīng)用血管鑄型技術(shù)及CT三維重建圖像處理后,都可清晰顯示子宮動(dòng)脈分支、分布及血管網(wǎng)吻合支情況,為婦產(chǎn)科疾病的臨床診斷、手術(shù)治療等方面提供血管形態(tài)學(xué)依據(jù),為指導(dǎo)子宮動(dòng)脈栓塞治療及新式婦產(chǎn)科手術(shù)的開(kāi)展提供解剖學(xué)平臺(tái)。
[Abstract]:Purpose: Through the further exploration and study of the technique and method of the blood vessel casting of the rabbit, the uterine artery, the uterine artery and the ovary were observed together by the image data obtained by the three-dimensional reconstruction of the human uterine vessels. The distribution of the branch, the uterine artery and the branch of the fallopian tube, and the study and distribution of the uterine arterial network, and further study the anastomosis of the uterine artery. To study. Methods: After the normal anesthesia of the rabbit, the abdominal aorta was inserted and the external arterial wire was ligated to the uterus of the rabbit and the bilateral fallopian tube and the ovary. the blood vessel casting mold is prepared through the steps of ethyl acetate and perchloroethylene and dibutyl phthalate, partial oil painting dye is fully stirred, and the filling agent is used as a filling agent; after the intubation, filling, corrosion, washing, sample rest, sample preservation and the like are performed to complete the blood vessel casting of the rabbit The preparation of the specimen is that the image of the human uterine artery can be driven into the blood vessel contrast agent through the line vein blood vessel, and then the uterus can be obtained by the three-dimensional reconstruction of the CT. vein blood vessel The results showed that the distribution of the uterine artery was clearly observed by the observation of the specimen of the uterus of the rabbit, and the two, three-stage branches and the distribution of the uterine vessels were observed. The distribution of the blood vessels in the branch of the ovary of the uterine artery and the branch of the fallopian tube and vascular anastomosis branch condition. The main performance is:1 through blood vessel The condition of the uterine vessels obtained by the casting: (1) the uterine artery The distribution of the vascular network and the distribution of the anastomosis:1 rabbit's uterine artery is tortuous and upward on both sides of the uterine body, and the uterine body part In that form of a spiral branch of the uterine artery, it is very small, but it can be observe by the magnifying glass or the scanning electron microscope that there is a clear traffic branch in the body of the uterus, and the distribution is very dense, which further proves that the uterine artery has obvious mutual blood supply tendency. The branch of the uterus, the ovary and the fallopian tube, and the descending branch failed to show the cause of the sample. The relationship between the branch of the vein and the ovary of the ovary.2. The contrast agent is injected into the human vein blood vessel, and the contrast agent is computed by the CT. Three-dimensional reconstruction of uterine artery image: (1) distribution of uterine artery:1 normal uterine artery The main branch of the cervix is divided into the branch of the bladder, the branch of the ureter, the ascending branch and the descending branch, so that the uterus and the ascending branch, the descending branch, the branch of the urinary bladder and the ureter branch can be clearly seen because of the small inflow of the small contrast agent of the blood vessel, and can not be shown. The upper ascending branch of the uterine artery, along the side edge of the uterine wall, is tortuous and upward, and the ascending branch of the uterine artery is seen to send a plurality of arcuate arteries along the way, a plurality of spiral arteries are arranged in the arch-shaped artery and distributed in the front of the uterus, and after reaching the level of the fundus of the uterus, the ascending branch of the uterine artery a plurality of branches, namely, a uterine fundus branch, an ovary branch and a fallopian tube branch, The ascending branch of the uterine artery is mainly the blood supply of the uterus, the ovary and the fallopian tube. (2) Distribution of the uterine artery and the distribution of the anastomosis:1. The uterine artery is centered on the central axis, and the two sides can be clearly seen. In the obvious traffic branch, although the distribution is relatively small, the distribution is more concentrated and dense, and further proves that the uterine artery has obvious mutual blood supply tendency. It can be seen that the upper uterine artery in the tortuous direction of the uterine wall can directly send the coarse eggs at the corner of the uterus. The nest is provided with a partial supply of blood to the ovary through the native ligament of the ovary. , ovary The blood supply of the uterine artery is not only the supply of the ovarian artery, but also the ovarian branch of the uterine artery. Conclusion: The branch, distribution of the uterine artery and the anastomosis of the vascular network can be clearly shown by the application of the vascular casting technique and the image processing of the three-dimensional reconstruction of the CT. and provides a blood vessel morphological basis for clinical diagnosis, operation treatment and the like of the obstetrics and gynecology diseases,
【學(xué)位授予單位】：大連醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R816.2;R711.74
本文編號(hào)：2482443
[Abstract]:Purpose: Through the further exploration and study of the technique and method of the blood vessel casting of the rabbit, the uterine artery, the uterine artery and the ovary were observed together by the image data obtained by the three-dimensional reconstruction of the human uterine vessels. The distribution of the branch, the uterine artery and the branch of the fallopian tube, and the study and distribution of the uterine arterial network, and further study the anastomosis of the uterine artery. To study. Methods: After the normal anesthesia of the rabbit, the abdominal aorta was inserted and the external arterial wire was ligated to the uterus of the rabbit and the bilateral fallopian tube and the ovary. the blood vessel casting mold is prepared through the steps of ethyl acetate and perchloroethylene and dibutyl phthalate, partial oil painting dye is fully stirred, and the filling agent is used as a filling agent; after the intubation, filling, corrosion, washing, sample rest, sample preservation and the like are performed to complete the blood vessel casting of the rabbit The preparation of the specimen is that the image of the human uterine artery can be driven into the blood vessel contrast agent through the line vein blood vessel, and then the uterus can be obtained by the three-dimensional reconstruction of the CT. vein blood vessel The results showed that the distribution of the uterine artery was clearly observed by the observation of the specimen of the uterus of the rabbit, and the two, three-stage branches and the distribution of the uterine vessels were observed. The distribution of the blood vessels in the branch of the ovary of the uterine artery and the branch of the fallopian tube and vascular anastomosis branch condition. The main performance is:1 through blood vessel The condition of the uterine vessels obtained by the casting: (1) the uterine artery The distribution of the vascular network and the distribution of the anastomosis:1 rabbit's uterine artery is tortuous and upward on both sides of the uterine body, and the uterine body part In that form of a spiral branch of the uterine artery, it is very small, but it can be observe by the magnifying glass or the scanning electron microscope that there is a clear traffic branch in the body of the uterus, and the distribution is very dense, which further proves that the uterine artery has obvious mutual blood supply tendency. The branch of the uterus, the ovary and the fallopian tube, and the descending branch failed to show the cause of the sample. The relationship between the branch of the vein and the ovary of the ovary.2. The contrast agent is injected into the human vein blood vessel, and the contrast agent is computed by the CT. Three-dimensional reconstruction of uterine artery image: (1) distribution of uterine artery:1 normal uterine artery The main branch of the cervix is divided into the branch of the bladder, the branch of the ureter, the ascending branch and the descending branch, so that the uterus and the ascending branch, the descending branch, the branch of the urinary bladder and the ureter branch can be clearly seen because of the small inflow of the small contrast agent of the blood vessel, and can not be shown. The upper ascending branch of the uterine artery, along the side edge of the uterine wall, is tortuous and upward, and the ascending branch of the uterine artery is seen to send a plurality of arcuate arteries along the way, a plurality of spiral arteries are arranged in the arch-shaped artery and distributed in the front of the uterus, and after reaching the level of the fundus of the uterus, the ascending branch of the uterine artery a plurality of branches, namely, a uterine fundus branch, an ovary branch and a fallopian tube branch, The ascending branch of the uterine artery is mainly the blood supply of the uterus, the ovary and the fallopian tube. (2) Distribution of the uterine artery and the distribution of the anastomosis:1. The uterine artery is centered on the central axis, and the two sides can be clearly seen. In the obvious traffic branch, although the distribution is relatively small, the distribution is more concentrated and dense, and further proves that the uterine artery has obvious mutual blood supply tendency. It can be seen that the upper uterine artery in the tortuous direction of the uterine wall can directly send the coarse eggs at the corner of the uterus. The nest is provided with a partial supply of blood to the ovary through the native ligament of the ovary. , ovary The blood supply of the uterine artery is not only the supply of the ovarian artery, but also the ovarian branch of the uterine artery. Conclusion: The branch, distribution of the uterine artery and the anastomosis of the vascular network can be clearly shown by the application of the vascular casting technique and the image processing of the three-dimensional reconstruction of the CT. and provides a blood vessel morphological basis for clinical diagnosis, operation treatment and the like of the obstetrics and gynecology diseases,
【學(xué)位授予單位】：大連醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R816.2;R711.74
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