頸椎骨質(zhì)增生的退變規(guī)律及相關(guān)研究
發(fā)布時間：2019-04-26 17:25
【摘要】：目的 研究頸椎退行性變的規(guī)律以及退行性變與性別、年齡的相關(guān)性。 材料與方法 隨機選擇580例做頸椎CT檢查的患者進行回顧性分析和總結(jié)，年齡13-70歲，其中男352例、女228例，所有患者均行16層螺旋CT（MSCT）檢查，選用B60骨窗掃描條件。0.75mm薄層重建后，在3D三維重建系統(tǒng)中進行標(biāo)準(zhǔn)橫軸位、矢狀位、冠狀位、曲面及VRT重建，然后觀察。主要觀察內(nèi)容為：頸椎各椎體、附件骨質(zhì)增生，韌帶鈣化骨化及生理曲度改變，并記錄各種征象的年齡、性別。用SPSS17.0軟件進行統(tǒng)計學(xué)相關(guān)性分析。 結(jié)果 1．頸椎椎體骨質(zhì)增生：（1）頸椎骨質(zhì)增生最早發(fā)生于頸1、2，平均年齡44-47歲，男性最早發(fā)生的年齡43.54±20.535歲，女性最早發(fā)生年齡46.00±20.535歲， P0.05，有性別差異；頸7椎體出現(xiàn)的最晚，平均年齡56.76±15.823歲。（2）按照頸椎骨質(zhì)增生發(fā)生的早晚依次為頸1、頸2椎體、頸5、6、頸4、7。頸3椎體骨質(zhì)增生最少見。 2．頸椎附件骨質(zhì)增生最早見于頸4-7，平均年齡為56-57歲左右，頸1-6椎體附件骨質(zhì)增生男性出現(xiàn)的年齡較女性稍大(P0.05)。 3．韌帶鈣化情況：（1）寰樞椎韌帶及前縱韌帶：寰樞椎韌帶及頸4-7前縱韌帶骨化、鈣化年齡最早，約51-52歲；頸2前縱韌帶出現(xiàn)的年齡最晚，平均年齡67.00±2.828歲。有男女差別(P0.05)，，女性較男性稍早出現(xiàn)韌帶鈣化骨化。（2）后縱韌帶：頸3后縱韌帶出現(xiàn)的年齡最早，平均年齡47.22±13.000歲，女性出現(xiàn)早，平均年齡45.00±12.780歲，男性出現(xiàn)的平均年齡為47.86±13.467歲。頸2水平后縱韌帶出現(xiàn)的年齡最晚，平均年齡55.33±13.125歲。大部分女性均較男性早出現(xiàn)后縱韌帶的鈣化骨化。（3）項韌帶：頸4-7水平項韌帶最早出現(xiàn)鈣化，平均年齡約50-53歲，頸2水平項韌帶出現(xiàn)鈣化的年齡最晚，平均年齡約59歲左右。男女無明顯差異(P0.05)。 4.頸椎曲度：頸椎曲度Y 直平均年齡45.04±15.190歲，反曲出現(xiàn)平均年齡為48.30±15.696歲，男女有差別(P0.05)，男性出現(xiàn)弧度變化的平均年齡較早，男性曲度Y 直的平均年齡為41.02±15.813歲，反曲的平均年齡為44.64±15.992歲，女性頸椎曲度Y 直的平均年齡為49.72±13.115歲，反曲的平均年齡為52.60±14.255歲。 結(jié)論 1.頸椎最早出現(xiàn)退行性改變的CT影像征象中：頸椎椎體骨質(zhì)增生最早出現(xiàn)的時間基本同頸椎生理曲度改變最早出現(xiàn)的時間，其中頸椎最早出現(xiàn)骨質(zhì)增生的椎體為頸1、2；韌帶鈣化骨化與椎體附件骨質(zhì)增生相比，其后縱韌帶鈣化年齡最早，韌帶鈣化骨化早于椎體附件（頸4-7）出現(xiàn)骨質(zhì)增生。 2.部分附件骨質(zhì)增生、寰樞椎韌帶、前縱及部分后縱韌帶鈣化骨化的出現(xiàn)女性早于男性。 3.MSCT由于其可多角度顯示圖像及分辨率高，有利于發(fā)現(xiàn)頸椎細微結(jié)構(gòu)的骨質(zhì)增生的改變，對于頸椎早期和輕度的骨質(zhì)增生的發(fā)現(xiàn)有較高價值。
[Abstract]:Objective to study the regularity of cervical degenerative change and its correlation with sex and age. Materials and methods A total of 580 patients with cervical CT were retrospectively analyzed and summarized. The age was 13 ~ 70 years old, including 352 males and 228 females. All patients underwent 16-slice spiral CT (MSCT), and all the patients were examined with 16-slice spiral CT (MSCT), and all the patients were examined with 16-slice spiral CT (MSCT). B60 bone window scanning condition was used. 0.75 mm thin slice reconstruction was performed in 3D 3D reconstruction system, including standard transverse, sagittal, coronal, curved and VRT reconstruction, and then observed. The main observations were as follows: cervical vertebrae, hyperosteogeny of appendages, calcification of ligaments and changes of physiological curvature, and the age and sex of all signs were recorded. Statistical correlation analysis was performed with SPSS17.0 software. Results 1. Cervical vertebra hyperosteogeny: (1) Cervical hyperosteogeny first occurred in C1, 2, with an average age of 44 to 47 years. The earliest occurrence of cervical hyperosteogeny was 43.54 鹵20.535 years in males and 46.00 鹵20.535 years in females, P0.05, There are gender differences; The mean age of C7 was 56.76 鹵15.823 years old. (2) according to the occurrence of cervical hyperosteogeny, the order of occurrence of cervical osteogeny was C1, C2, 5, 6, 4, 7, respectively. Cervical 3 vertebrae osteogeny hyperplasia is the most rare. 2. Cervical adnexal osteogeny hyperplasia was first seen at C4-7, with an average age of 56-57 years. The age of cervical adnexal hyperosteogeny was slightly older in males than in females (P0.05). 3. Calcification of ligament: (1) atlantoaxial ligament and anterior longitudinal ligament: atlantoaxial ligament and cervical 4 / 7 anterior longitudinal ligament ossification, the age of calcification was the earliest, about 51 ~ 52 years old; The mean age of the anterior longitudinal ligament was 67.00 鹵2.828 years old. (2) the posterior longitudinal ligament: the age of the posterior longitudinal ligament was the earliest, the average age was 47.22 鹵13.000 years, the female appeared earlier, the average age was 45.00 鹵12.780 years, the average age of the posterior longitudinal ligament was 47.22 鹵13.000 years, the average age of the posterior longitudinal ligament was 45.00 鹵12.780 years, and the average age of the posterior longitudinal ligament was 45.00 鹵12.780 years. The average age of males was 47.86 鹵13.467 years old. The age of posterior longitudinal ligament at neck 2 level was the last, with an average age of 55.33 鹵13.125 years. The calcification of the posterior longitudinal ligament occurred earlier in most women than in men. (3) ligaments: the first calcification occurred in the cervical 4-7 level ligaments, with an average age of about 50-53 years, and the age of calcification of the cervical-2-level ligaments was the latest. The average age is about 59. There was no significant difference between men and women (P0.05). 4. Cervical curvature: the average age of Y-straight cervical curvature was 45.04 鹵15.190 years, and the mean age of reflexion was 48.30 鹵15.696 years old. There was significant difference between men and women (P0.05). The mean age of Y-straight was 41.02 鹵15.813 years for male, 44.64 鹵15.992 years for reverse curvature, 49.72 鹵13.115 years for female cervical curvature, 52.60 鹵14.255 years for female cervical curvature, and 41.02 鹵15.813 years for male, 44.64 鹵15.992 years for reverse curvature, 49.72 鹵13.115 years for female cervical curvature and 52.60 鹵14.255 years for female cervical curvature. Conclusion 1. Among the CT imaging signs of the earliest degenerative changes of cervical vertebrae: the earliest appearance time of cervical vertebra osteogeny hyperplasia was the same as the earliest appearance of cervical physiological curvature change, in which the first cervical vertebra appeared hyperosteogeny was C1, 2, and that of cervical vertebra hyperosteogeny was the same as that of cervical vertebra physiological curvature change. Compared with the hyperosteogeny of the vertebral appendage, the calcification of the ligaments was the earliest, and the calcification of the ligaments was earlier than that of the appendages of the vertebrae (C4 / 7). 2. The ossification of accessory osteogeny, atlantoaxial ligament, anterior longitudinal ligament and posterior longitudinal ligament was earlier in female than in male. Because of its multi-angle image and high resolution, 3.MSCT is helpful to find the change of bone hyperplasia in the fine structure of cervical vertebra. It is of high value for early and mild cervical bone hyperplasia.
【學(xué)位授予單位】：泰山醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2013
【分類號】：R681.5;R816.8
本文編號：2466246
[Abstract]:Objective to study the regularity of cervical degenerative change and its correlation with sex and age. Materials and methods A total of 580 patients with cervical CT were retrospectively analyzed and summarized. The age was 13 ~ 70 years old, including 352 males and 228 females. All patients underwent 16-slice spiral CT (MSCT), and all the patients were examined with 16-slice spiral CT (MSCT), and all the patients were examined with 16-slice spiral CT (MSCT). B60 bone window scanning condition was used. 0.75 mm thin slice reconstruction was performed in 3D 3D reconstruction system, including standard transverse, sagittal, coronal, curved and VRT reconstruction, and then observed. The main observations were as follows: cervical vertebrae, hyperosteogeny of appendages, calcification of ligaments and changes of physiological curvature, and the age and sex of all signs were recorded. Statistical correlation analysis was performed with SPSS17.0 software. Results 1. Cervical vertebra hyperosteogeny: (1) Cervical hyperosteogeny first occurred in C1, 2, with an average age of 44 to 47 years. The earliest occurrence of cervical hyperosteogeny was 43.54 鹵20.535 years in males and 46.00 鹵20.535 years in females, P0.05, There are gender differences; The mean age of C7 was 56.76 鹵15.823 years old. (2) according to the occurrence of cervical hyperosteogeny, the order of occurrence of cervical osteogeny was C1, C2, 5, 6, 4, 7, respectively. Cervical 3 vertebrae osteogeny hyperplasia is the most rare. 2. Cervical adnexal osteogeny hyperplasia was first seen at C4-7, with an average age of 56-57 years. The age of cervical adnexal hyperosteogeny was slightly older in males than in females (P0.05). 3. Calcification of ligament: (1) atlantoaxial ligament and anterior longitudinal ligament: atlantoaxial ligament and cervical 4 / 7 anterior longitudinal ligament ossification, the age of calcification was the earliest, about 51 ~ 52 years old; The mean age of the anterior longitudinal ligament was 67.00 鹵2.828 years old. (2) the posterior longitudinal ligament: the age of the posterior longitudinal ligament was the earliest, the average age was 47.22 鹵13.000 years, the female appeared earlier, the average age was 45.00 鹵12.780 years, the average age of the posterior longitudinal ligament was 47.22 鹵13.000 years, the average age of the posterior longitudinal ligament was 45.00 鹵12.780 years, and the average age of the posterior longitudinal ligament was 45.00 鹵12.780 years. The average age of males was 47.86 鹵13.467 years old. The age of posterior longitudinal ligament at neck 2 level was the last, with an average age of 55.33 鹵13.125 years. The calcification of the posterior longitudinal ligament occurred earlier in most women than in men. (3) ligaments: the first calcification occurred in the cervical 4-7 level ligaments, with an average age of about 50-53 years, and the age of calcification of the cervical-2-level ligaments was the latest. The average age is about 59. There was no significant difference between men and women (P0.05). 4. Cervical curvature: the average age of Y-straight cervical curvature was 45.04 鹵15.190 years, and the mean age of reflexion was 48.30 鹵15.696 years old. There was significant difference between men and women (P0.05). The mean age of Y-straight was 41.02 鹵15.813 years for male, 44.64 鹵15.992 years for reverse curvature, 49.72 鹵13.115 years for female cervical curvature, 52.60 鹵14.255 years for female cervical curvature, and 41.02 鹵15.813 years for male, 44.64 鹵15.992 years for reverse curvature, 49.72 鹵13.115 years for female cervical curvature and 52.60 鹵14.255 years for female cervical curvature. Conclusion 1. Among the CT imaging signs of the earliest degenerative changes of cervical vertebrae: the earliest appearance time of cervical vertebra osteogeny hyperplasia was the same as the earliest appearance of cervical physiological curvature change, in which the first cervical vertebra appeared hyperosteogeny was C1, 2, and that of cervical vertebra hyperosteogeny was the same as that of cervical vertebra physiological curvature change. Compared with the hyperosteogeny of the vertebral appendage, the calcification of the ligaments was the earliest, and the calcification of the ligaments was earlier than that of the appendages of the vertebrae (C4 / 7). 2. The ossification of accessory osteogeny, atlantoaxial ligament, anterior longitudinal ligament and posterior longitudinal ligament was earlier in female than in male. Because of its multi-angle image and high resolution, 3.MSCT is helpful to find the change of bone hyperplasia in the fine structure of cervical vertebra. It is of high value for early and mild cervical bone hyperplasia.
【學(xué)位授予單位】：泰山醫(yī)學(xué)院
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2013
【分類號】：R681.5;R816.8
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