【摘要】：目的 本文的通過模體模擬分析數(shù)字減影血管造影（DSA）和多層螺旋CT（MSCT）對血管成像對比度、分辨率和密度值等的差異，尋找出不同病人不同造影劑濃度對DSA和CT成像的影響因素，從而根據(jù)病人和造影劑濃度的不同選擇診斷冠心病的檢查方式。 材料與方法 本文采用由丙烯酸樹脂平板和水箱自制的水模體，模擬不同密度的造影劑和不同管徑的血管，并分別在DSA和MSCT下進行成像掃描，分析兩種成像設備的物理性能的差異、二者圖像的血管在噪聲密度分辨率和密度值的差異。由兩名資深影像科醫(yī)師采用雙盲法對兩種設備做出的圖像進行綜合分析，選擇能分辨的最小血管影像作為低分辨率對比度影像。 結(jié)果 根據(jù)不同成像系統(tǒng)的特點，將劑量優(yōu)化方案分為2組，并用兩種成像系統(tǒng)分別對血管體模進行檢查。MSCT分別進行高劑量和低劑量掃描，獲取一組數(shù)據(jù)；DSA進行不同透視和電影模式，，獲取第二組圖像數(shù)據(jù)。 結(jié)論 數(shù)字減影血管造影DSA成像質(zhì)量和照射劑量產(chǎn)生影響，是由系統(tǒng)中的透視條件及攝影條件照射野和附加濾過的大小，影像增強器尺寸、視角的幾何放大。都可影響字減影血管造影DSA產(chǎn)生的照射劑量和成像質(zhì)量；而MSCT系統(tǒng)中的掃描方式、機架轉(zhuǎn)速、探測器寬度、FOV大小等則對CT成像質(zhì)量和輻射劑量產(chǎn)生影響。高劑量條件下，兩種設備做出的兩組影像沒有明顯差異。但在低劑量條件，獲得滿足影像診斷要求的情況下，MSCT比DSA具有更高的輸出劑量。因此，在不影響診斷要求的前提下，選擇DSA合理的成像方式，可以在獲得高質(zhì)量影像同時，降低病人所受的輻射劑量。
[Abstract]:Objective to analyze the differences of contrast, resolution and density between digital subtraction angiography (DSA) and multi-slice spiral CT (MSCT) (MSCT) in digital subtraction angiography (DSA) and multi-slice spiral angiography (CT (MSCT). To find out the influencing factors of different contrast agent concentration on DSA and CT imaging in different patients, so as to select the examination method of diagnosing coronary heart disease according to the patient and contrast medium concentration. Materials and methods A water template made of acrylic resin plate and water tank was used to simulate different density contrast agents and vessels with different diameters, and the images were scanned under DSA and MSCT, respectively. The difference of the physical performance between the two imaging devices and the difference of the noise density resolution and density value between the two images are analyzed. A double blind method was used by two senior imaging physicians to analyze the images made by the two kinds of equipment. The smallest vessel image which could be distinguished was selected as the low resolution contrast image. Results according to the characteristics of different imaging systems, the dose optimization scheme was divided into two groups, and the phantom was examined by two kinds of imaging systems. MSCT was scanned with high dose and low dose respectively to obtain a set of data. DSA performs different perspective and movie modes to obtain the second set of image data. Conclusion the effect of DSA imaging quality and irradiation dose on digital subtraction angiography is due to the size of irradiation field and additional filtering, the size of image intensifier and the geometric magnification of the angle of view under the fluoroscopic and photographic conditions in the system. [WT5 "HZ] conclusion [WT5" BZ] [WT5 "BZ] Both of them can affect the irradiation dose and imaging quality of DSA, while the scanning mode, frame rotation speed, detector width and FOV size in MSCT system have influence on the imaging quality and radiation dose of CT. At high dose, there was no significant difference between the two groups of images made by the two devices. However, under the condition of low dose, MSCT has higher output dose than DSA under the condition of satisfying the requirement of imaging diagnosis. Therefore, on the premise that the diagnostic requirements are not affected, the reasonable imaging mode of DSA can obtain high-quality images and reduce the radiation dose of the patients at the same time.
【學位授予單位】：泰山醫(yī)學院
【學位級別】：碩士
【學位授予年份】：2012
【分類號】：R816.2

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