本文選題：體力活動(dòng)　切入點(diǎn)：心肺耐力　出處：《北京體育大學(xué)》2012年博士論文

【摘要】：目的：通過(guò)橫斷面調(diào)查和運(yùn)動(dòng)干預(yù)實(shí)驗(yàn)對(duì)40-49歲男性體力活動(dòng)(PA)、心肺耐力(CRF)與代謝綜合征(MS)發(fā)病率及相關(guān)風(fēng)險(xiǎn)因素之間的相關(guān)性進(jìn)行研究。探討CRF在改善MS風(fēng)險(xiǎn)因素所起的作用。進(jìn)一步探討量和強(qiáng)度提高V02max的機(jī)制。 實(shí)驗(yàn)1：CRF、PA與MS發(fā)病率以及相關(guān)風(fēng)險(xiǎn)因素相關(guān)性研究 通過(guò)對(duì)246名無(wú)心血管疾病的男性進(jìn)行PA調(diào)查和CRF測(cè)試。比較二者與各風(fēng)險(xiǎn)指標(biāo)之間的相關(guān)性。結(jié)果：CRF與MS發(fā)病率及風(fēng)險(xiǎn)因素具有很高的相關(guān)性,CRF水平較高的人群,MS發(fā)病率和風(fēng)險(xiǎn)因素的比例減少,其0R風(fēng)險(xiǎn)值下降至0.337-0.873。 實(shí)驗(yàn)2：不同運(yùn)動(dòng)劑量干預(yù)對(duì)V02max和MS相關(guān)風(fēng)險(xiǎn)因素效果影響的研究 通過(guò)將受試對(duì)象隨機(jī)分為4組,進(jìn)行12周的運(yùn)動(dòng)干預(yù)：(1)不運(yùn)動(dòng)組(15人)；(2)小量中強(qiáng)度組(16人)；(3)小量大強(qiáng)度組(14人)；(4)大量大強(qiáng)度組(13人)；測(cè)試干預(yù)前后V02max和血脂指標(biāo)。結(jié)果：運(yùn)動(dòng)干預(yù)組受試對(duì)象V02max均有所提升,分別提高了4、15.8和17.6%,V02max在不同量同強(qiáng)度組增加的幅度相似。量和強(qiáng)度均會(huì)對(duì)各血脂水平產(chǎn)生一定的影響,大量大強(qiáng)度獲得的效益更大。 實(shí)驗(yàn)3：不同運(yùn)動(dòng)劑量干預(yù)對(duì)CRF效果影響的機(jī)制研究 通過(guò)對(duì)受試對(duì)象進(jìn)行干預(yù)后,對(duì)其血常規(guī)、血管軟硬度和超聲心動(dòng)等指標(biāo)進(jìn)行監(jiān)測(cè)。結(jié)果：(1)量和強(qiáng)度均會(huì)引起RBC、Hb和baPWV改善,但只有大量大強(qiáng)度組呈顯著性差異。(2)量和強(qiáng)度都有利于心肌功能的改善,大強(qiáng)度組收縮能力顯著增強(qiáng)：而舒張能力只有在大量大強(qiáng)度組出現(xiàn)顯著增強(qiáng)。(3)大強(qiáng)度組a-vDiff顯著提高,強(qiáng)度是引起a-vDiff改善的主要因素。結(jié)論： (1)CRF要比PA更能預(yù)測(cè)MS發(fā)病率和相關(guān)風(fēng)險(xiǎn)因素,并與之呈劑量-效應(yīng)關(guān)系,高水平的CRF更有利于改善MS風(fēng)險(xiǎn)。 (2)強(qiáng)度要比量更有利于V02max提高；強(qiáng)度和量均有利于血脂、血壓的改善,大量大強(qiáng)度獲得的效益更大。 (3)V02max提高主要在于量和強(qiáng)度引起心功能和動(dòng)靜脈氧分壓差的改善,雖然兩個(gè)大強(qiáng)度組提高V02max的效果相似,但其機(jī)制有所不同。 (4)小量大強(qiáng)度V02max提高主要是通過(guò)心臟收縮功能和動(dòng)脈氧分壓差的改善引起的。而大量大強(qiáng)度V02max提高卻是收縮能力、舒張能力以及外周機(jī)制等因素共同作用產(chǎn)生的。
[Abstract]:Objective: to study the relationship between CRF and metabolic syndrome (MS) incidence and related risk factors in men aged 40-49 years old by cross-sectional investigation and exercise intervention experiment. To explore the role of CRF in improving the risk factors of MS. To further explore the mechanism of increasing the quantity and intensity of V02max. A study on the correlation between CRFPA and MS incidence and related risk factors in experiment 1:. A PA survey and a CRF test were conducted in 246 men without cardiovascular disease. The correlation between the two was compared with the risk indicators. Results there was a high correlation between the incidence and risk factors of the disease and the risk factors. The proportion of incidence and risk factors of MS decreased, The risk value of 0R decreased to 0.337-0.873. Experiment 2: effects of different exercise doses on risk factors related to V02max and MS. The subjects were randomly divided into 4 groups. After 12 weeks of exercise intervention, V02max and blood lipid index were measured before and after intervention. Results: the V02max of the subjects in the exercise intervention group was increased, and the V02max of the subjects in the exercise intervention group was increased, and there were 16 patients in the moderate intensity group and 14 patients in the high intensity group, and 13 patients in the high intensity group were tested before and after the intervention, and the results showed that the V02max of the subjects in the exercise intervention group increased, and that of the patients in the exercise intervention group was higher than that in the control group before and after the intervention. The increase of V02max was similar to that of the same intensity group. Both the volume and the intensity had a certain effect on the level of blood lipid, and the benefit of a large amount of high intensity was more than that of the other groups. Experiment 3: mechanism of effect of different exercise doses on the effect of CRF. After intervention, the blood routine, blood vessel hardness and echocardiography were monitored. Results the volume and intensity of 1% could improve the HB and baPWV of RBCs. However, only a large number of high intensity groups showed significant difference. The volume and intensity were beneficial to the improvement of myocardial function. The contractility of the high intensity group was significantly enhanced, while the diastolic ability was significantly enhanced only in a large number of high intensity groups. The strength is the main factor that causes the improvement of a-vDiff. Conclusion:. CRF can predict the incidence of MS and related risk factors better than PA, and has a dose-effect relationship with it. High level of CRF is more helpful to improve the risk of MS. (2) the intensity should be more favorable to the increase of V02max than the quantity, and both the intensity and the quantity are beneficial to the improvement of blood lipids and blood pressure, and the benefit of a large amount of high intensity is greater. The increase of V02max was mainly due to the improvement of cardiac function and arteriovenous oxygen partial pressure difference due to the volume and intensity. Although the effect of two high intensity groups on V02max was similar, the mechanism was different. 4) the increase of small amount of high intensity V02max is mainly caused by the improvement of cardiac systolic function and arterial oxygen partial pressure difference, while a large number of high intensity V02max increases are caused by the combination of systolic ability, diastolic ability and peripheral mechanism.
【學(xué)位授予單位】：北京體育大學(xué)
【學(xué)位級(jí)別】：博士
【學(xué)位授予年份】：2012
【分類號(hào)】：G804.21

【共引文獻(xiàn)】

相關(guān)期刊論文 前10條

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