貴州省赫章縣鎘污染區(qū)人群健康損害狀況調(diào)查及損害指標(biāo)關(guān)系探討
發(fā)布時(shí)間：2019-06-22 13:14
【摘要】：目的了解貴州省赫章縣環(huán)境鎘污染區(qū)人群健康狀況。方法通過隨機(jī)抽樣方法獲得調(diào)查對象,采集人群尿樣,等離子發(fā)射光譜-質(zhì)譜法(ICP-MS)檢測尿鎘,分光光度法測定N-乙酰-β-D-氨基葡萄糖苷酶(NAG)和肌酐,放射免疫法測定β2-微球蛋白等指標(biāo)。結(jié)果完成人群尿樣篩查共1351人份,污染區(qū)948人,對照區(qū)403人。污染區(qū)與對照區(qū)人群尿鎘水平分別為8.79和2.93μg/g Cr,差異有統(tǒng)計(jì)學(xué)意義(P0.05),尿鎘陽性率分別為10.8%和1.2%。兩地區(qū)人群尿β2-MG和尿NAG水平差異無統(tǒng)計(jì)學(xué)意義。污染區(qū)與對照區(qū)人群聯(lián)合反應(yīng)率分別為1.6%和0.5%。結(jié)論赫章縣環(huán)境鎘污染對人群存在潛在健康危害,聯(lián)合檢測尿鎘、NAG和β2-微球蛋白能夠全面反映環(huán)境鎘污染的健康危害。
[Abstract]:Objective To study the health status of the people in the polluted area in the environment of Hezhang County, Guizhou Province. Methods The samples were obtained by random sampling. The urine and urine samples were collected by ICP-MS, and the N-B-1-D-amino-grape glycanase (NAG) and myostatin were determined by spectrophotometry. The method of radioimmunoassay (RIA) for the determination of 2-microglobulin and other indexes. Results The total number of urine samples in the population was 1351,948 in the contaminated area and 403 in the control area. The urine level in the contaminated area and the control area was 8.79 and 2.93. m u.g/ g Cr, respectively. The difference was statistically significant (P0.05). The positive rate of urinary infection was 10.8% and 1.2%, respectively. There was no significant difference in the level of urine,2-MG and urinary NAG in the two regions. The combined rate of reaction between the contaminated area and the control area was 1.6% and 0.5%, respectively. Conclusion The environmental pollution in Huzhang county is a potential health hazard to the population, and the combined detection of urine, NAG and CD2-microglobulin can reflect the health hazard of environmental pollution.
【作者單位】： 中國疾病預(yù)防控制中心環(huán)境與健康相關(guān)產(chǎn)品安全所;貴州省疾病預(yù)防控制中心職業(yè)病所;貴州省環(huán)境科學(xué)研究設(shè)計(jì)院;
【基金】：環(huán)保部貴州赫章鎘污染區(qū)污染現(xiàn)狀及人群健康調(diào)查(No.EH-2009-12-09)
【分類號】：R131
[Abstract]:Objective To study the health status of the people in the polluted area in the environment of Hezhang County, Guizhou Province. Methods The samples were obtained by random sampling. The urine and urine samples were collected by ICP-MS, and the N-B-1-D-amino-grape glycanase (NAG) and myostatin were determined by spectrophotometry. The method of radioimmunoassay (RIA) for the determination of 2-microglobulin and other indexes. Results The total number of urine samples in the population was 1351,948 in the contaminated area and 403 in the control area. The urine level in the contaminated area and the control area was 8.79 and 2.93. m u.g/ g Cr, respectively. The difference was statistically significant (P0.05). The positive rate of urinary infection was 10.8% and 1.2%, respectively. There was no significant difference in the level of urine,2-MG and urinary NAG in the two regions. The combined rate of reaction between the contaminated area and the control area was 1.6% and 0.5%, respectively. Conclusion The environmental pollution in Huzhang county is a potential health hazard to the population, and the combined detection of urine, NAG and CD2-microglobulin can reflect the health hazard of environmental pollution.
【作者單位】： 中國疾病預(yù)防控制中心環(huán)境與健康相關(guān)產(chǎn)品安全所;貴州省疾病預(yù)防控制中心職業(yè)病所;貴州省環(huán)境科學(xué)研究設(shè)計(jì)院;
【基金】：環(huán)保部貴州赫章鎘污染區(qū)污染現(xiàn)狀及人群健康調(diào)查(No.EH-2009-12-09)
【分類號】：R131
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