【摘要】：目的了解溫室作業(yè)女性人群長期農(nóng)藥暴露對(duì)妊娠結(jié)局的影響。方法隨機(jī)抽取2010年3月—2014年12月在濰坊市婦幼保健院等3家單位婦產(chǎn)科生育住院的產(chǎn)婦為研究對(duì)象,其中在孕前及孕期累計(jì)且連續(xù)從事溫室作業(yè)至少2年以上者449人為暴露組,不從事溫室作業(yè)且不接觸農(nóng)藥的同醫(yī)院產(chǎn)婦152人為對(duì)照組。通過問卷調(diào)查和查閱資料等方式獲得女性農(nóng)藥暴露情況、既往生育史、妊娠期疾患、妊娠結(jié)局等;并根據(jù)農(nóng)藥暴露強(qiáng)度將暴露組分為低、中、高暴露組,統(tǒng)計(jì)各組不良妊娠結(jié)局發(fā)生情況。結(jié)果調(diào)查人群的不良妊娠結(jié)局共166例,發(fā)生率為18.53%(166/896);其中年齡35歲者不良妊娠結(jié)局發(fā)生率為31.25%(45/144);有異常孕產(chǎn)史者不良妊娠結(jié)局發(fā)生率為47.83%(11/23),溫室作業(yè)產(chǎn)婦的不良妊娠結(jié)局發(fā)生率為21.21%(140/660)。不同農(nóng)藥暴露量的產(chǎn)婦早產(chǎn)、自然流產(chǎn)、死胎及死產(chǎn)、出生缺陷發(fā)生率差異有統(tǒng)計(jì)學(xué)意義(P0.05),均隨暴露量的增加而升高。結(jié)論溫室作業(yè)女性人群長期農(nóng)藥暴露可能導(dǎo)致早產(chǎn)、流產(chǎn)、死胎及死產(chǎn)、出生缺陷等不良妊娠結(jié)局。
[Abstract]:Objective to investigate the effect of long-term pesticide exposure on pregnancy outcome in women exposed to greenhouse. Methods from March 2010 to December 2014, parturients hospitalized in obstetrics and gynaecology from three units, such as Weifang Maternal and Child Health Hospital, were randomly selected as the subjects of the study. Among them, 449 women who had been engaged in greenhouse operation for at least 2 years before pregnancy and more than 2 years during pregnancy were exposed group, and 152 parturients in the same hospital who were not engaged in greenhouse operation and were not exposed to pesticides were taken as control group. Through questionnaire survey and access to data, female pesticide exposure, past reproductive history, pregnancy diseases, pregnancy outcomes and so on; According to the intensity of pesticide exposure, the exposed groups were divided into low, middle and high exposure groups, and the occurrence of adverse pregnancy outcomes in each group was counted. Results A total of 166 cases of adverse pregnancy outcomes were investigated, the incidence of adverse pregnancy outcomes was 18.53% (166 鈮，

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