【摘要】：目的了解寧夏銀川、吳忠兩市兒童青少年維生素D營(yíng)養(yǎng)狀況,為預(yù)防兒童青少年維生素D不足與缺乏提供合理依據(jù)。方法在銀川市2區(qū)和吳忠市隨機(jī)抽取小學(xué)、初中和高中,采用分層整群抽樣的方法抽取班級(jí)。排除佝僂病、克羅恩病、心血管疾病及肝腎疾病患者,以及近3月內(nèi)服用過(guò)維生素D補(bǔ)充劑的兒童青少年,共選取7~18歲對(duì)象2 167名。采集研究對(duì)象空腹靜脈血,采用酶聯(lián)免疫吸附法(ELISA法)測(cè)定其血清25(OH)D的濃度。結(jié)果銀川、吳忠兩市兒童青少年血清25(OH)D濃度中位數(shù)為51.46 nmol/L,四分位數(shù)間距為61.46 nmol/L,維生素D充足、不足、缺乏檢出率分別為51.9%,14.1%,34.0%。不足檢出率以7歲最高,8~13歲隨著年齡的增長(zhǎng)呈升高趨勢(shì),至14歲開(kāi)始逐漸降低。7~18歲各年齡組兒童青少年缺乏檢出率依次為31.9%,27.9%,20.8%,30.1%,36.7%,2.4%,29.8%,32.3%,35.3%,47.5%,37.3%,32.8%,各年齡組均較高。不同年齡組間維生素D水平及缺乏檢出率比較,差異均有統(tǒng)計(jì)學(xué)意義(H=43.086,P0.01;χ~2=11.156,P=0.001)�；亍h族兒童青少年維生素D水平、不足與缺乏檢出率比較,差異均無(wú)統(tǒng)計(jì)學(xué)意義(P值均0.05)。結(jié)論銀川、吳忠兩市7~18歲兒童青少年維生素D水平較低,維生素D缺乏檢出率較高;隨年齡增長(zhǎng),兒童青少年血清維生素D水平逐漸降低,不足、缺乏檢出率升高。
[Abstract]:Objective to investigate the vitamin D nutritional status of children and adolescents in Yinchuan and Wu Zhong in Ningxia, and to provide reasonable basis for preventing deficiency and deficiency of vitamin D in children and adolescents. Methods the primary, middle and senior middle schools were randomly selected from Yinchuan District 2 and Wuzhong City, and the classes were sampled by stratified cluster sampling. Patients with rickets, Crohn's disease, cardiovascular diseases, liver and kidney diseases, and children and adolescents who had taken vitamin D supplements in recent three months were excluded. A total of 2,167 subjects aged 718 years were selected. Fasting venous blood was collected and the serum concentration of 25 (OH) D was determined by enzyme linked immunosorbent assay (ELISA). Results the median concentration of 25 (OH) D in serum of children and adolescents in Yinchuan and Wu Zhong cities was 51.46 nmol/L, / quartile interval. The interval of vitamin D was 61.46 nmol/L,. The deficiency rate was 51.9 nmol/L, and 14.1g, respectively. 34.0. The highest detection rate was in the age of 7, and the rate of deficiency in the age of 813 increased with the increase of age, and gradually decreased at the age of 14. The detectable rate of the deficiency of children and adolescents in the age group of 718 years was 31.927. 9% and 20.8% 30.1yr, respectively. 36.7and 2.4and 29.8m, 32.33.35 and 37.5, and 37.3 and 32.8. all the age groups are higher than the other three, and they are 37.3% and 37.3%, 37.3%, 37.3%, 37.3%, 37.3% and 37.3%, respectively. The levels of vitamin D and the prevalence of vitamin D deficiency were significantly different among different age groups (P 0.01; 蠂 2 11.156 P 0.001). There was no significant difference in vitamin D levels between children and adolescents of Han nationality (P < 0.05). Conclusion the levels of vitamin D and vitamin D deficiency in children and adolescents aged 7 ~ 18 years in Yinchuan and Wu Zhong are lower and the detection rate of vitamin D deficiency is higher, and the serum vitamin D level of children and adolescents decreases gradually with the increase of age.
【作者單位】： 寧夏醫(yī)科大學(xué)公共衛(wèi)生與管理學(xué)院;
【分類號(hào)】：R179

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