發(fā)布時(shí)間：2018-11-24 09:59

【摘要】：比較檸檬酸蘋(píng)果酸鈣、碳酸鈣、牦牛骨粉、L-天門(mén)冬氨酸鈣這四種鈣補(bǔ)充劑溶解后對(duì)胃酸的消耗情況,及對(duì)大鼠胃液分泌的影響,為消費(fèi)者選擇合適的鈣劑提供參考。通過(guò)體外模擬人工胃環(huán)境,測(cè)定四種鈣劑在人工胃液中釋放鈣離子所消耗的胃酸量;使用大鼠幽門(mén)結(jié)扎法建立大鼠胃液分泌模型,觀察不同鈣劑對(duì)大鼠胃液量、胃酸酸度及胃酸分泌量的影響。實(shí)驗(yàn)表明檸檬酸蘋(píng)果酸鈣溶解后使人工胃液中氫離子含量顯著增加(P0.01),碳酸鈣、牦牛骨粉和L-天門(mén)冬氨酸鈣溶解后則使人工胃液中氫離子含量顯著降低(P0.05);大鼠體內(nèi)實(shí)驗(yàn)中,檸檬酸蘋(píng)果酸鈣組和牦牛骨粉組大鼠的胃液量、胃酸酸度及胃酸分泌量均顯著減少(P0.01),L-天門(mén)冬氨酸鈣組大鼠的胃液量、胃酸酸度及胃酸分泌量均顯著增多(P0.01),碳酸鈣組大鼠的胃液量、胃酸酸度、胃酸分泌量與正常對(duì)照組大鼠相比無(wú)顯著性差異(P0.05)。
[Abstract]:To compare the consumption of calcium citrate calcium carbonate yak bone powder and L-aspartate calcium on gastric acid consumption and the effect of calcium citrate on gastric juice secretion in order to provide reference for consumers to choose suitable calcium. By simulating the artificial stomach environment in vitro, the amount of gastric acid consumed by the release of calcium ion from the artificial gastric juice by four kinds of calcium agents was determined. The gastric juice secretion model was established by pyloric ligation in rats, and the effects of different calcium on gastric juice volume, acidity and secretion of gastric acid were observed. The results showed that the hydrogen ion content in the artificial gastric juice increased significantly after the dissolution of calcium citrate (P0.01), and the hydrogen ion content in the artificial gastric juice decreased significantly after the dissolution of calcium carbonate, yak bone powder and L-aspartate calcium (P0.05). In vivo, the gastric juice, acid acidity and gastric acid secretion of rats in calcium citrate malate group and yak bone powder group were significantly decreased (P0.01), and the gastric juice volume in L-aspartate calcium group was significantly decreased (P0.01). Gastric acid acidity and gastric acid secretion were significantly increased (P0.01). There was no significant difference in gastric juice, gastric acid acidity and gastric acid secretion between the calcium carbonate group and the normal control group (P0.05).
【作者單位】： 華南理工大學(xué)輕工食品學(xué)院;暨南大學(xué)醫(yī)學(xué)院;千林女性營(yíng)養(yǎng)與健康研究中心;
【基金】：十二五科技支撐計(jì)劃子課題(2012BAD33B11)
【分類號(hào)】：R151;TS201.4

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