【摘要】：目的了解2005年和2012年廣西武鳴縣農(nóng)村壯族育齡婦女的血漿鉛濃度水平及其差異。方法以電感耦合等離子體質(zhì)譜法檢測(cè)2005年和2012年在廣西壯族自治區(qū)武鳴縣進(jìn)行的兩次橫斷面調(diào)查中所收集的200名和182名18~30歲婦女血漿標(biāo)本的鉛濃度,結(jié)合問卷調(diào)查資料分析血漿鉛濃度超過意大利健康人群血漿鉛暴露參考值上限的相關(guān)因素。結(jié)果調(diào)查婦女的血漿鉛濃度中位數(shù)由2005年的0.99 ng/ml上升至2012年的1.78 ng/ml,血漿鉛濃度超過參考值上限婦女所占比例由2005年的49.50%上升到2012年的85.69%。單因素分析發(fā)現(xiàn),婦女血漿鉛超過參考值上限的相關(guān)因素有居住地、文化程度、婚姻狀況、體質(zhì)指數(shù)等,差異有統(tǒng)計(jì)學(xué)意義(P0.05);經(jīng)多因素logistics回歸調(diào)整混雜因素后,均未發(fā)現(xiàn)上述因素與婦女血漿鉛濃度超過參考值上限比例有關(guān)(P0.05)。結(jié)論 2012年武鳴縣農(nóng)村育齡婦女的血漿鉛濃度遠(yuǎn)高于2005年,需進(jìn)一步調(diào)查其原因并加強(qiáng)該縣鉛污染防控和監(jiān)測(cè)。
[Abstract]:Objective to investigate the plasma lead levels and their differences between 2005 and 2012 in rural Zhuang women of childbearing age in Wuming County, Guangxi. Methods two cross-sectional surveys were conducted in Wuming County, Guangxi Zhuang Autonomous region in 2005 and 2012 by inductively coupled plasma mass spectrometry (ICP-MS) to detect the plasma lead concentrations of 200 and 182 women aged 1830 years. The related factors of plasma lead concentration exceeding the upper limit of reference value of plasma lead exposure in healthy people in Italy were analyzed by questionnaire survey. Results the median plasma lead concentration of women increased from 0. 99 ng/ml in 2005 to 1. 78 ng/ml, in 2012. The proportion of women who exceeded the maximum reference value increased from 49.50% in 2005 to 85. 69% in 2012. Univariate analysis showed that there were significant differences in the relative factors of women's plasma lead over the upper limit of reference value, such as residence, education, marital status, body mass index, etc. (P0.05); after multivariate logistics regression, the confounding factors were adjusted. The above factors were not found to be related to the proportion of plasma lead concentration exceeding the upper limit of reference value (P0.05). Conclusion the plasma lead concentration in rural women of childbearing age in Wuming County in 2012 is much higher than that in 2005. It is necessary to further investigate the causes and strengthen the prevention and control of lead pollution in Wuming County.
【作者單位】： 北京大學(xué)生育健康研究所國(guó)家衛(wèi)生計(jì)生委生育健康重點(diǎn)實(shí)驗(yàn)室;廣西壯族自治區(qū)武鳴縣婦幼保健院;
【基金】：美國(guó)國(guó)家地理空氣與水保護(hù)基金資助項(xiàng)目(GEFC10-13)
【分類號(hào)】：R114

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