【摘要】：目的：了解新疆伊犁地區(qū)7～14歲哈薩克族兒童超重、肥胖、血壓水平和高血壓的發(fā)生狀況，比較分析體質(zhì)指數(shù)(BMI)及血壓與代謝指數(shù)的關(guān)系。方法：采用隨機(jī)整群抽樣方法,抽取新疆伊犁地區(qū)7～14歲哈薩克族學(xué)齡兒童2438例，進(jìn)行身高、體重、腰圍、臀圍、皮褶厚度、血壓測(cè)量，并計(jì)算BMI；分別檢測(cè)28例肥胖高血壓組、58例單純性肥胖組及60例正常對(duì)照組兒童的代謝指數(shù)(總膽固醇TC、甘油三脂TG、高密度脂蛋白HDL、低密度脂蛋白LDL、空腹血糖FPG、空腹胰島素FINS)，計(jì)算胰島素抵抗指數(shù)(HOMA-IR)，并分析3組間各指標(biāo)均數(shù)的差異，體質(zhì)指數(shù)(BMI)、收縮壓(SBP)及舒張壓(DBP)與各指標(biāo)的相關(guān)關(guān)系。結(jié)果：(1)新疆伊犁地區(qū)7～14歲哈薩克族兒童肥胖率為1.64%(40/2438)，超重率為5.13%(25/2438)；(2)兒童收縮壓(SBP)平均水平(94±13)mmHg，，舒張壓(DBP)平均水平為(60±9)mmHg；高血壓患病率5.7%(138/2438)；(3)SBP、DBP及高血壓患病率與性別、年齡、BMI、腰圍、臀圍、皮褶厚度均呈正相關(guān)。(4)3組間BMI、SBP、DBP、TC、TG、HDL、LDL、FPG、FINS、HOMA-IR的均數(shù)相比均差異顯著(P0.05)，以肥胖高血壓組兒童TC、LDL、FPG、HOMA-IR的均數(shù)值最大，肥胖高血壓組兒童HDL的均數(shù)值最小。(5)Pearson相關(guān)法分析：BMI與TC、LDL、FPG、FINS、HOMA-IR有直接相關(guān)關(guān)系，與HDL不存在直接相關(guān)關(guān)系，與TG無(wú)相關(guān)關(guān)系；SBP、DBP與TC、HDL、LDL、FPG、FINS、HOMA-IR不存在直接相關(guān)關(guān)系，與TG無(wú)相關(guān)關(guān)系。(6)多重線性回歸分析：以TC、TG、HDL、LDL、FPG、FINS、HOMA-IR為自變量，以BMI為因變量，TC、HDL、LDL、HOMA-IR進(jìn)入方程；以SBP為因變量，TC、HDL、LDL，HOMA-IR進(jìn)入方程；以DBP為因變量，TG、HDL、LDL，HMOA-IR進(jìn)入方程。結(jié)論：與漢族兒童相比，哈薩克族兒童肥胖率介于中小城市與富裕鄉(xiāng)村水平間；血壓平均水平較國(guó)內(nèi)兒童低，高血壓患病率處于國(guó)內(nèi)外同年齡段兒童的中等水平，肥胖與哈薩克族兒童高血壓患病率密切相關(guān)；兒童肥胖及肥胖伴高血壓的發(fā)生，與血脂紊亂、胰島素抵抗指數(shù)關(guān)系密切，是否與血糖異常有關(guān)系需深入研究。血脂紊亂、血糖異常、胰島素抵抗指數(shù)與血壓的關(guān)系也需要近一步研究與探討。
[Abstract]:Objective: to investigate the prevalence of overweight, obesity, blood pressure and hypertension among Kazakh children aged 7 ~ 14 years in Yili area, Xinjiang, and to compare the relationship between body mass index (BMI), blood pressure and metabolic index. Methods: 2438 Kazakh school-age children aged 7 or 14 years in Yili area of Xinjiang were selected by random cluster sampling. Height, weight, waist circumference, hip circumference, skinfold thickness, blood pressure were measured and BMI; was calculated. Metabolic index (total cholesterol, TC, triglyceride, TG, high density lipoprotein, HDL, low density lipoprotein, LDL, fasting insulin) in 58 simple obese children and 60 normal controls were measured. The insulin resistance index (HOMA-IR) was calculated by FINS), and the differences of the mean values of each index among the three groups were analyzed. Body mass index (BMI),) systolic blood pressure (SBP) and diastolic blood pressure (DBP) were correlated with each index. Results: (1) the obesity rate was 1.64% (40 / 2438) and overweight rate was 5.13% (25 / 2438); (/ 2) among Kazak children aged 714 years in Yili, Xinjiang. The mean (SBP) level of systolic blood pressure (SBP) was (94 鹵13) mmHg, diastolic blood pressure (DBP) was (60 鹵9) mmHg; and the prevalence of SBP,DBP, hypertension and sex was (60 鹵9) mmHg;. Age, waist circumference, hip circumference and skinfold thickness were positively correlated. (4) the mean number of BMI,SBP,DBP,TC,TG,HDL,LDL,FPG,FINS,HOMA-IR was significantly different among the three groups (P0.05). The average value of HDL was the lowest in obese hypertensive children. (5) Pearson correlation analysis showed that there was a direct correlation between HDL and HDL, but no direct correlation with HDL, and there was no direct correlation between Pearson and TC,HDL,LDL,FPG,FINS,HOMA-IR. (6) multiple linear regression analysis: using TC,TG,HDL,LDL,FPG,FINS,HOMA-IR as independent variable, BMI as dependent variable, SBP as dependent variable, and DBP as dependent variable. Conclusion: compared with Han children, the obesity rate of Kazak children is between the middle and small cities and the rich rural areas, the average blood pressure is lower than that of the domestic children, and the prevalence of hypertension is at the middle level of the same age children at home and abroad. Obesity is closely related to the prevalence of hypertension in Kazakh children, and the occurrence of obesity with hypertension in children is closely related to dyslipidemia and insulin resistance index, and whether there is a relationship between obesity and abnormal blood glucose needs further study. The relationship between hyperlipidemia, abnormal blood glucose, insulin resistance index and blood pressure also needs further study and discussion.
【學(xué)位授予單位】：新疆醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2012
【分類號(hào)】：R179

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