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中國西部城市孕婦末梢血礦物質(zhì)元素檢測(cè)水平分析及建議參考值研究

發(fā)布時(shí)間:2018-06-17 09:27

  本文選題:末梢血礦物質(zhì)元素 + 妊娠期; 參考:《蘭州大學(xué)》2013年碩士論文


【摘要】:目的 分析中國西部三省份3339例18-42歲妊娠中期孕婦末梢血鈣、鐵、鋅、銅、鎂五種礦物質(zhì)元素含量的檢測(cè)結(jié)果,了解上述五種礦物質(zhì)元素在該人群中缺乏和過量現(xiàn)狀及其原因,分析五種礦物質(zhì)元素在地區(qū)、年齡之間的差異,確立孕婦末梢血五種元素參考范圍值。 方法 采取整群隨機(jī)抽樣的方法選取中國西部甘肅、陜西、四川三省18-42歲定期做孕期檢查、資料完整的妊娠中期健康孕婦3339例為樣本。使用多通道火焰原子吸收光譜儀(BH5100型)檢測(cè)孕婦末梢血中鈣、鐵、鋅、銅、鎂五種元素含量,對(duì)各省份各年齡組孕婦末梢血五種元素含量對(duì)比分析,最后用百分位數(shù)法制定五種元素參考范圍值。 結(jié)果 1.研究樣本的基本情況:本研究樣本來自甘肅、陜西、四川三省份,共3339例,平均年齡27.09±4.44歲,其中甘肅和陜西25-歲組例數(shù)最多,而四川省18-歲組最多,各省孕婦年齡分布符合各省的一般特征,代表性較好。 2.三省孕婦鈣、鐵、鋅、銅、鎂元素現(xiàn)狀:三省份孕婦鈣元素含量均值在正常范圍值之內(nèi),甘肅省含量最低,陜西省最高,不同年齡組中30-歲組最高,且孕婦鈣元素含量有隨孕婦年齡最高而增高的趨勢(shì),三省份孕婦鈣缺乏較為嚴(yán)重,其中陜西省缺乏率最低為25.94%,甘肅省缺乏率最高甚至達(dá)到了53.18%,孕婦鈣過量現(xiàn)象也存在:孕婦鐵元素均值在正常范圍之內(nèi),三省份含量差異具有統(tǒng)計(jì)學(xué)意義(P0.05),其中四川省最低,甘肅省最高,不同年齡組中25-歲組最高,孕婦鐵缺乏嚴(yán)重,甘肅省缺乏率最低8.47%,四川省缺乏率最高59.30%,鐵過量的現(xiàn)象只在甘肅省出現(xiàn);鋅元素含量均值在正常范圍之內(nèi),三省份含量差異具有統(tǒng)計(jì)學(xué)意義(P0.05),其中四川最低,甘肅最高,不同年齡組中25-歲組最高,孕婦鋅缺乏現(xiàn)象較為普遍,甘肅缺乏率5.10%,四川缺乏率最高13.99%,鋅過量例數(shù)較少,不普遍;銅元素含量均值在正常范圍之內(nèi),三省份均值有統(tǒng)計(jì)學(xué)差異(P0.05),甘肅省最低,四川省最高,不同年齡組中18-歲組最高,銅缺乏率四川最低0.10%,甘肅最高16.61%,銅過量現(xiàn)象存在但比較罕見;鎂元素含量均值在正常范圍之內(nèi),四川省均值最低,甘肅最高,不同年齡組中25-歲組最高,鎂缺乏和過量現(xiàn)象均不普遍。 3.末梢血五種元素參考值范圍的確立:按照不同省份、不同年齡組(18-歲組、25-歲組、30-歲組)確立末梢血鈣、鐵、鋅、銅、鎂元素參考值范圍,分別取第2.5、10、16、25、50、75、84、90、97.5百分位數(shù)值,確立期望參考值范圍(P16~P84%)和臨界參考值范圍(P2.5~P97.5),為臨床檢測(cè)提供參考依據(jù)。 結(jié)論 1.三省份妊娠中期孕婦末梢血中鈣、鐵、銅、鎂元素含量因自然環(huán)境、氣候條件、膳食結(jié)構(gòu)不同而表現(xiàn)出地區(qū)差異,但三省份各年齡組孕婦各元素含量平均值均在正常參考值范圍內(nèi)。 2.鈣、鐵、鋅元素三省份各年齡組孕婦缺乏均較為嚴(yán)重,銅、鎂元素缺乏較少。 3.孕婦末梢血中鈣、鐵、銅、鎂元素過量現(xiàn)象均存在,但僅限于個(gè)別孕婦。 4.確立三省份各年齡組末梢血鈣、鐵、銅、鎂元素參考值范圍,為臨床診斷提供參考依據(jù)。
[Abstract]:Purpose

The results of the determination of five mineral elements in maternal peripheral blood calcium , iron , zinc , copper and magnesium in 3339 pregnant women aged 18 - 42 in western China were analyzed .

method

Three hundred and thirty - nine children aged 18 - 42 in western Gansu , Shaanxi and Sichuan were randomly sampled by cluster random sampling . The contents of Ca , Fe , Zn , Cu and Mg in the peripheral blood of pregnant women were analyzed by multi - channel flame atomic absorption spectrometer ( BH5100 type ) .

Results

1 . The basic information of study samples : The samples from Gansu , Shaanxi and Sichuan were 3339 cases , the average age was 27.09 鹵 4.44 years . Among them , the average age was 27.09 鹵 4.44 years . Among them , the age distribution of pregnant women in Gansu and Shaanxi was the largest , and the age distribution of pregnant women in every province was in accordance with the general characteristics of the provinces .

2 . Current status of calcium , iron , zinc , copper and magnesium in pregnant women in three provinces is the lowest in the three provinces , the highest in Gansu Province , the highest in Shaanxi Province , the highest in Shaanxi Province , the highest in Shanxi Province , and the highest in the three provinces .
The mean value of zinc element is within the normal range , the difference of three provinces has statistical significance ( P0.05 ) , among which Sichuan is the lowest , Gansu is the highest , in different age group , 25 - year old group is the highest , pregnant woman ' s zinc deficiency is common , Gansu lack rate is 5 . 10 % , Sichuan lack rate is highest 13.99 % , zinc excess number is less , not widespread ;
The mean value of copper element was within the normal range , the mean of three provinces had statistical significance ( P0.05 ) , the lowest in Gansu Province , the highest in Sichuan Province , the highest in the 18 - year - old group in different age groups , the lowest copper deficiency rate in Sichuan was 0.10 % , the highest in Gansu was 16.61 % , and the copper overdose was rare ;
The mean value of magnesium element is within the normal range , the lowest in Sichuan province , the highest in Gansu , the highest in the age group of 25 - year old in different age groups , and the magnesium deficiency and excessive phenomenon are not common .

3 . The reference value range of the five elements of peripheral blood was established : according to different provinces , different age groups ( aged 18 - year group , 25 - year group , 30 - year group ) established the reference value range of peripheral blood calcium , iron , zinc , copper and magnesium element . The reference value range ( P16 ~ P84 % ) and critical reference value range ( P2.5 ~ P97.5 ) were established , and the reference basis was provided for clinical detection .

Conclusion

1 . The contents of calcium , iron , copper and magnesium in the peripheral blood of pregnant women in three provinces were different from those of the natural environment , climatic conditions and dietary structure , but the average values of all the pregnant women in each age group were within the normal reference value range .

2 . The deficiency of pregnant women in all age groups in the three provinces of calcium , iron and zinc is more serious , and the deficiency of copper and magnesium is less .

3 . The excessive phenomenon of calcium , iron , copper and magnesium in the peripheral blood of pregnant women exists , but it is limited to individual pregnant women .

4 . To establish the reference value range of blood calcium , iron , copper and magnesium in each age group in three provinces and provide reference for clinical diagnosis .
【學(xué)位授予單位】:蘭州大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2013
【分類號(hào)】:R153.1

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