本文選題：斑馬魚(yú) + 認(rèn)知�。� 參考：《毒理學(xué)雜志》2017年03期

【摘要】：正1前言隨著科學(xué)技術(shù)的發(fā)展,新化學(xué)物質(zhì)日益增多。目前部分化合物的毒性已被闡明,而大部分化學(xué)物質(zhì)對(duì)健康的潛在影響尚未完全清楚,所以對(duì)外源化合物的危險(xiǎn)度評(píng)價(jià)顯得尤為重要與緊迫。傳統(tǒng)毒理學(xué)實(shí)驗(yàn)常用嚙齒類(lèi)動(dòng)物作為實(shí)驗(yàn)對(duì)象,但是其花費(fèi)大,實(shí)驗(yàn)周期長(zhǎng),難以對(duì)大量物質(zhì)進(jìn)行高通量試驗(yàn)。隨著3R(reduction,replacement and refinement)原則的實(shí)施,整
[Abstract]:With the development of science and technology, new chemical substances are increasing day by day. At present, the toxicity of some compounds has been clarified, but the potential health effects of most chemicals have not been fully understood, so the risk assessment of exogenous compounds is particularly important and urgent. Rodents are often used as experimental objects in traditional toxicological experiments, but they are expensive and have a long experimental period, so it is difficult to carry out high-throughput experiments on a large number of substances. With the implementation of the 3R / R reduction / replacement and definition principle,
【作者單位】： 汕頭大學(xué)醫(yī)學(xué)院公共衛(wèi)生與預(yù)防醫(yī)學(xué)教研室;
【基金】：廣東省自然科學(xué)基金(2014A030313474)
【分類(lèi)號(hào)】：R114

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