本文選題：日照市 + 碘缺乏地區(qū)��； 參考：《山東大學》2013年碩士論文

【摘要】：[目的] 針對當前補碘思路重在貫徹“科學補碘”的防治策略,調(diào)查日照市居民碘營養(yǎng)水平,為科學補碘與防治碘缺乏病提供基礎資料與科學依據(jù)。 [方法] 在日照市所轄區(qū)域范圍內(nèi),對居民生活飲用水水碘水平、對居民飲食有著重要影響的富碘食品的含碘量水平、8-10歲兒童尿碘水平、患甲狀腺疾病的病例組及對照組尿碘水平、居民食用碘鹽狀況等進行調(diào)查分析。 [結果] 1.該研究在GB/T5750.5-2006生活飲用水中碘化物的硫酸鈰催化分光光度法的基礎上,建立了測定生活飲用水中微量碘的測定方法,該方法與GB/T5750.5-2006生活飲用水中碘化物的硫酸鈰催化分光光度法比較,有著操作簡單、在試驗過程中易于控制等優(yōu)點,能夠適用于碘缺乏地區(qū)開展生活飲用水中碘的調(diào)查中大批量水樣的測定。 2.該調(diào)查在日照市范圍內(nèi)共收集水樣數(shù)據(jù)3369份,總體上水碘中位數(shù)為4.1μg/L,所轄區(qū)縣水碘中位數(shù)分別為：東港區(qū),4.0-g/L；嵐山區(qū),6.6μg/L；五蓮縣,4.21μg/L；莒縣,3.2μg/L。其水碘頻數(shù)分布經(jīng)統(tǒng)計學檢驗,差異有統(tǒng)計學意義(x2=77.96,p0.01)。日照市轄區(qū)內(nèi)的所有鄉(xiāng)鎮(zhèn)的水碘中位數(shù)均小于10μg/L,其頻數(shù)分布也有差異,其中東港區(qū)三莊鎮(zhèn),莒縣龍山、陵陽、桑園、庫山、東莞等鄉(xiāng)鎮(zhèn)水碘中位數(shù)為1μg/L,沿海鄉(xiāng)鎮(zhèn)與內(nèi)陸鄉(xiāng)鎮(zhèn)比較,其水碘中位數(shù)分別為6.6μg/L與3.8μg/L；其水碘分布差異具有統(tǒng)計學意義(x2=69.41,p0.01)。 3.針對市售富碘食品含碘量的差異,將富碘食品劃分為高碘食品和其他富碘食品,建立富碘食品含碘量的測定方法。采用容量分析方法測定高碘食品的含碘量；利用碘催化砷鈰氧化還原法測定含碘量相對較低的食品中的含碘量。通過富碘試樣的合理分類,消除了含碘樣品測定時取樣的盲目性,在一定程度上克服了試樣處理液在前處理過程中經(jīng)反復稀釋造成的誤差。在含碘食品測定中采用適當?shù)姆治龇椒?重復測定6次不同含碘量的試樣,其相對標準偏差在2.60%-9.52%。 4.對富碘食品含碘量進行檢測分析,給出不同富碘含碘量的參考值。鮮蛤、鮮蟶、鮮海虹、蝦皮、蝦米中的含碘量較低,其平均值均不超過2mg/kg;濕海帶、成品即食海帶、干裙帶菜、紫菜中含碘量平均值在19.6～118.0mg/kg,以干裙帶菜含碘量較高；干海帶是碘的良好來源,其含碘量在164～3256mg/kg,平均值為1050.8mg/kg。5.該調(diào)查共收集8-10歲兒童即時尿樣476份,8-10歲兒童尿碘中位數(shù)為150.6μg/L；在患有甲狀腺疾病的病例組與對照組尿碘水平調(diào)查中,病例組尿碘中位數(shù)略高于對照組,而兩組尿碘頻數(shù)分布差異無統(tǒng)計學意義(x2=5.92,p0.05)；共收集食用鹽樣品1322份,其碘鹽合格率96.9%、合格碘鹽食用率為95.9%、非碘鹽率1.1%、碘鹽覆蓋率98.9%。 [結論] 1.該研究建立的測定生活飲用水中微量碘的測定方法,具有操作簡單、試驗過程易于控制等優(yōu)點,適用于碘缺乏地區(qū)開展生活飲用水中碘的調(diào)查中大批量水樣的測定。通過生活飲用水中碘含量的調(diào)查確定了日照市飲用水中水碘的分布特點,得出了日照市沿海鄉(xiāng)鎮(zhèn)居民飲用水水碘中位數(shù)比內(nèi)陸鄉(xiāng)鎮(zhèn)略高的結論,為開展碘缺乏病的防治和飲用水水源的選擇提供了理論依據(jù)。 2.針對市售富碘食品含碘量的差異,將富碘食品劃分為高碘食品和其他富碘食品,建立富碘食品含碘量的測定方法。對日照市部分富碘食品含碘量進行檢測分析,給出不同富碘含碘量的參考值。不同食品中含碘量差異較大,不同富碘食品中含碘量也有較大差異,不同產(chǎn)地的同一富碘食品其含碘量也存在較大的差異,同一產(chǎn)品的不同的取樣位置含碘量也有所不同。 3.日照市屬碘缺乏地區(qū),日照市生活飲用水水碘的分布不均衡；食物中的碘含量差異較大,僅從飲食角度補碘難以滿足機體需要；實施補碘措施后,人群碘營養(yǎng)水平達到充足且稍偏高狀態(tài),隨著人們對科學補碘意識的提高,碘營養(yǎng)水平更趨向合理。
[Abstract]:Purpose of the project

According to the current idea of iodine supplementation , the iodine nutrition level of residents in Rizhao City is investigated and the basic information and scientific basis for scientific iodine supplementation and iodine deficiency prevention are provided .

Methodology

In the area of Rizhao city , the iodine level of drinking water in drinking water was studied , the iodine content of iodine - rich food with important influence on residents ' diet , the urinary iodine level of children aged 8 - 10 years , the level of urinary iodine in children with thyroid diseases and the iodine level in the control group were investigated and analyzed .

The result is not valid .

1 . The determination method of trace iodine in drinking water is established based on the cerium sulfate catalytic spectrophotometric method of iodide in drinking water of GB / T 5750 . 5 - 2006 . The method has the advantages of simple operation , easy control during testing and the like , and can be applied to the determination of large batch of water samples in the investigation of iodine deficiency in living drinking water in iodine deficiency area .

2 . The survey collected 3369 samples of water samples in Rizhao City , the median of total water iodine was 4.1 渭g / L , and the median water iodine number in the districts was 4 . 0 - g / L .
Lanshan region , 6.6渭g / L ;
Wulian county , 4.21渭g / L ;
There was statistical significance ( x2 = 77.96 , p0.01 ) in the distribution of iodine frequency in Juxian County , 3.2 渭g / L . The median number of water iodine in all villages and towns in Rizhao City is less than 10渭g / L , and its frequency distribution is different . Among them , the median of iodine in villages and towns in Donggang Town , Longshan , Lingyang , Sanyuan , Kuyama , Dongguan and other towns is 1 渭g / L , and the median number of water iodine in coastal towns and towns is 6.6 渭g / L and 3.8 渭g / L , respectively .
The difference of water iodine distribution was significant ( x2 = 69.41 , p0.01 ) .

3 . According to the difference of iodine content in iodine - enriched food , iodine - enriched food was divided into high - iodine food and other iodine - rich foods , and the method for measuring iodine content in iodine - enriched food was established . The iodine content of high - iodine food was determined by volumetric analysis method .
The iodine content in foods with relatively low iodine content was determined by the method of iodine - catalyzed arsenic - cerium oxide reduction . By reasonable classification of iodine - rich samples , the blindness of sampling during the determination of iodine - containing samples was eliminated , and the errors caused by repeated dilution in the pretreatment process were overcome . The relative standard deviation was 2.60 % - 9.52 % .

4 . The iodine content of iodine - enriched food was analyzed and the reference value of iodine content of different iodine - rich foods was given . The iodine content of fresh clam , fresh razor clam , fresh sea rainbow , shrimp skin and shrimp was lower than 2mg / kg ; the average value of iodine content in wet kelp , finished product instant kelp , dried undaria and Thallus Porphyrae was 19.6 - 118.0 mg / kg , with higher iodine content in dried undaria .
Dry kelp is a good source of iodine . Its iodine content is 164 ~ 3256mg / kg , the average value is 101.8mg / kg . 5 . The survey collected 476 samples of children aged 8 - 10 years . The median of urinary iodine in children aged 8 - 10 years is 150.6 渭g / L .
In the case group with thyroid disease and the control group , the median urinary iodine number was slightly higher than that in the control group , while there was no significant difference between the two groups ( x2 = 5.92 , p0.05 ) .
The qualified rate of iodized salt was 96.9 % , the rate of qualified iodized salt was 95.9 % , the rate of non - iodized salt was 1.1 % , and the rate of iodized salt was 98 . 9 % .

Conclusion

1 . The method of determination of trace iodine in drinking water is established by the research . It has the advantages of simple operation , easy control and so on . It is suitable for the determination of iodine in drinking water in drinking water in the area of iodine deficiency . By investigating the iodine content in drinking water , the conclusion that the median number of iodine in drinking water in drinking water in the coastal towns of Rizhao city is higher than that of the inland villages and towns is obtained , which provides the theoretical basis for the prevention and control of iodine deficiency disease and the choice of drinking water source .

2 . According to the difference of iodine content in iodine - rich foods , the iodine - rich food was divided into high - iodine food and other iodine - rich foods . The iodine content of iodine - rich foods in Rizhao city was analyzed . The iodine content of different iodine - rich foods was significantly different .

3 . Rizhao city belongs to iodine deficiency area , and the distribution of iodine in drinking water in Rizhao city is not balanced ;
the iodine content in the food is different , and only the iodine supplementation in the diet is difficult to meet the needs of the organism ;
After the iodine supplementation , the iodine nutrition level of the population is sufficient and slightly higher , and the iodine nutrition level is more reasonable with the improvement of scientific iodine supplementation awareness .

【學位授予單位】：山東大學
【學位級別】：碩士
【學位授予年份】：2013
【分類號】：R151

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本文編號：1893426