本文選題：超重 + 肥胖��； 參考：《山西醫(yī)科大學(xué)》2017年碩士論文

【摘要】：目的:通過(guò)飲食,運(yùn)動(dòng)和行為教育的體重綜合干預(yù),糾正成年超重及肥胖患者的不良飲食習(xí)慣和生活習(xí)慣,減輕患者體重,降低其血糖、血脂、血壓、血尿酸等水平,預(yù)防或改善“五高”狀態(tài),減少或延緩患者慢性代謝性疾病的發(fā)生發(fā)展。探索可推廣的針對(duì)我國(guó)成年超重及肥胖患者減重的綜合干預(yù)模式,為患者自發(fā)進(jìn)行體重管理提供科學(xué)的依據(jù)和指導(dǎo)。方法:從山西和諧健康體檢中心確診為超重及肥胖的患者中篩選出自愿進(jìn)行體重干預(yù)試驗(yàn)的研究對(duì)象41例。對(duì)研究對(duì)象進(jìn)行8周的體重綜合干預(yù),包括:飲食干預(yù)、運(yùn)動(dòng)干預(yù)和行為教育。研究對(duì)象在干預(yù)前后檢測(cè)觀察指標(biāo)。觀察指標(biāo)包括身高、體重、腰圍、血壓等生理指標(biāo);血糖、血脂、血尿酸、血尿素氮、血肌酐等血液生化指標(biāo)。分析比較檢測(cè)結(jié)果。結(jié)果:1、整個(gè)干預(yù)試驗(yàn)后,研究對(duì)象的體重、BMI、WC、SBP、DBP、FPG、2h PG、TG、TC、LDL-C、BUA與干預(yù)前相比明顯降低,差異具有統(tǒng)計(jì)學(xué)意義(P0.05),其余觀察指標(biāo)均有所改善,但差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。2、干預(yù)第4周末,研究對(duì)象的體重、BMI、WC、SBP、FPG、2h PG、TG、BUA與干預(yù)前相比明顯下降(P0.05),其余觀察指標(biāo)有改善趨勢(shì),但差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。3、干預(yù)第8周結(jié)束時(shí),研究對(duì)象的體重、BMI、WC、FPG、2h PG、TC、TG、BUA與干預(yù)4周末相比明顯下降(P0.05),其余觀察指標(biāo)有所改善,但差異無(wú)統(tǒng)計(jì)學(xué)意義(P0.05)。4、經(jīng)8周的干預(yù)試驗(yàn)后,有超重患者8人BMI24 kg/m2,轉(zhuǎn)歸率為53.3%;肥胖患者11人BMI28 kg/m2,轉(zhuǎn)歸率為42.3%;有18人血糖轉(zhuǎn)歸到正常水平,轉(zhuǎn)歸率為69.2%;有16人血甘油三酯轉(zhuǎn)歸到正常水平,轉(zhuǎn)歸率為69.6%;有11人血壓轉(zhuǎn)歸到正常水平,轉(zhuǎn)歸率為61.1%;有14人血尿酸轉(zhuǎn)歸到正常水平,轉(zhuǎn)歸率為60.9%。結(jié)論:對(duì)超重及肥胖患者進(jìn)行飲食、運(yùn)動(dòng)和行為教育綜合干預(yù),能夠有效降低患者體重,改善其糖脂代謝及胰島素抵抗,降低血壓、血尿酸水平,預(yù)防或改善“五高”狀態(tài),延緩或避免肥胖相關(guān)并發(fā)癥的發(fā)生發(fā)展。且本次的體重綜合干預(yù)模式依從性較好,值得推廣應(yīng)用。
[Abstract]:Objective: to correct the unhealthy eating habits and living habits of overweight and obese adults by comprehensive intervention of diet, exercise and behavioral education, and to reduce the body weight, blood glucose, blood lipid, blood pressure, blood uric acid and so on. To prevent or improve the "five high" state, reduce or delay the occurrence and development of chronic metabolic diseases in patients. To explore a popularized comprehensive intervention model for weight loss of overweight and obese adults in China, and to provide scientific basis and guidance for spontaneous weight management of patients. Methods: 41 subjects who were diagnosed as overweight and obese in Shanxi harmonious Health examination Center were selected. The subjects were given 8 weeks weight comprehensive intervention, including diet intervention, exercise intervention and behavioral education. The observation indexes were detected before and after intervention. The indexes included height, weight, waist circumference, blood pressure, blood glucose, blood lipid, serum uric acid, blood urea nitrogen, blood creatinine and other blood biochemical indexes. Analysis and comparison of test results. Results: after the whole intervention trial, the body weight of the study subjects was significantly lower than that before intervention, and the difference was statistically significant (P 0.05), but there was no significant difference between the two groups at the end of the 4th week of intervention. The body weight of the subjects was significantly lower than that before the intervention (P 0.05), but there was no significant difference between the two groups (P 0.05 路3). At the end of the 8th week of intervention, the body weight of the subjects was significantly lower than that of the control group (P < 0.05), but there was no significant difference between the two groups at the end of the 8th week of intervention. The body weight of the subjects was significantly decreased compared with that at the end of 4 weeks, and the other indexes were improved, but the difference was not statistically significant (P 0.05. 4). After 8 weeks of intervention, there was no significant difference between the two groups. There were 8 overweight patients with BMI24 kg / m2, with a return rate of 53.3%; 11 obese patients with BMI28 kg / m2, with a return rate of 42.3%; 18 people with blood glucose returning to the normal level, with a return rate of 69.2%; and 16 people with triglyceride returned to normal level. The rate of return was 69.6, the blood pressure of 11 people was returned to normal level, the rate of return was 61.1, and the rate of blood uric acid returned to normal level was 60.9. Conclusion: comprehensive intervention of diet, exercise and behavior education in overweight and obese patients can effectively reduce body weight, improve glucose and lipid metabolism and insulin resistance, lower blood pressure and serum uric acid level, prevent or improve "five high" status. Delay or avoid the occurrence and development of obesity related complications. And the weight of the comprehensive intervention model compliance is good, worthy of promotion and application.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級(jí)別】：碩士
【學(xué)位授予年份】：2017
【分類號(hào)】：R151.41

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