本文選題：流感病毒　切入點：流行特征　出處：《中國病原生物學(xué)雜志》2015年04期

【摘要】：目的分析湖州市流行性感冒病毒型別分布,闡述流行特征,為制定預(yù)防控制措施提供依據(jù)。方法湖州市兩家流感哨點監(jiān)測醫(yī)院按天登記收集流感樣病例(ILI)監(jiān)測數(shù)據(jù),網(wǎng)絡(luò)實驗室對ILI標本進行核酸檢測。整理湖州市2010-2014年ILI監(jiān)測和病原學(xué)檢測結(jié)果進行綜合分析。結(jié)果 2010-2014年,湖州市共核酸檢測流感樣病例標本6 917份,陽性1 305份,陽性率為18.87%;其中乙型占44.37%、季H3型占41.23%、新甲H1型占14.18%、混合感染占0.22%、無季H1型檢出。每年都存在冬春季流行高峰,2010年、2012年和2014年存在夏秋季次高峰。各年份間(χ2=172.33,P0.05)、各年齡組間(χ2=145.05,P0.05)陽性率差異存在統(tǒng)計學(xué)意義,男女間(χ2=3.94,P=0.05)陽性率差異無統(tǒng)計學(xué)意義。結(jié)論湖州市流感病毒流行具有明顯的季節(jié)性,最高峰為冬春季、次高峰為夏秋季;存在甲型和乙型流感病毒交替轉(zhuǎn)換流行的現(xiàn)象,且病毒型別轉(zhuǎn)換后都會引起一波流行高峰,季H1型可能已經(jīng)被新甲H1型所取代。建議在流行期和病毒型別轉(zhuǎn)換期重點做好監(jiān)測、預(yù)警和防控工作,并對人群感染情況和夏秋季次高峰形成原因進行進一步的研究分析。
[Abstract]:Objective to analyze the distribution of influenza virus types in Huzhou City, and to provide basis for the prevention and control measures.Methods Influenza surveillance data were collected from two influenza sentinel surveillance hospitals in Huzhou on a daily basis. Nucleic acid was detected in ILI samples in network laboratory.The results of ILI surveillance and etiology detection in Huzhou City from 2010 to 2014 were analyzed.Results from 2010 to 2014, there were 6 917 samples of influenza like cases detected by nucleic acid in Huzhou, and 1 305 were positive, the positive rate was 18.87, in which the B type was 44.37, the season H3 type was 41.23%, the neomethylH1 type was 14.18%, the mixed infection was 0.22%, and no season H1 type was detected.There are winter and spring epidemic peaks every year, summer and autumn secondary peaks in 2010, 2012 and 2014.There was significant difference in the positive rate between different age groups (蠂 2 / 172.33 / P 0.05), but there was no significant difference in the positive rate between male and female (蠂 2 / 3.94 / P 0.05) among different age groups (蠂 ~ (2) = 145.05 / P ~ (0.05)), but there was no significant difference between male and female (蠂 ~ (2) = 3.94 / P ~ (0.05)).Conclusion the influenza virus epidemic in Huzhou city is seasonal, the highest is in winter and spring, the second peak is in summer and autumn, and there is the phenomenon of influenza A and B influenza virus alternating with each other, and the change of virus type will cause a wave of epidemic peak.Season H 1 may have been replaced by new type H 1.It is suggested that surveillance, early warning, prevention and control should be carried out during the epidemic period and the period of virus type conversion, and further study and analysis should be made on the situation of infection in the population and the cause of the peak in summer and autumn.
【作者單位】： 浙江省湖州市疾病預(yù)防控制中心;
【分類號】：R511.7;R181.3

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本文編號：1707844