本文關(guān)鍵詞：浙江省中年居民體質(zhì)指數(shù)、腰圍身高比及膳食脂肪對(duì)血清瘦素水平的影響　出處：《衛(wèi)生研究》2017年02期 　論文類型：期刊論文

  更多相關(guān)文章： 體質(zhì)指數(shù) 腰圍身高比 膳食脂肪 瘦素

【摘要】：目的分析浙江省中年居民體質(zhì)指數(shù)(BMI)、腰圍身高比(WHtR)及膳食脂肪攝入情況與血清瘦素水平的相關(guān)性。方法采用分層隨機(jī)抽樣法,于2014年12月從浙江省抽取4個(gè)區(qū)縣513名30~65歲調(diào)查對(duì)象,采用3天24小時(shí)膳食回顧法進(jìn)行膳食調(diào)查,同時(shí)測(cè)量其身高、體重、腰圍及血清瘦素濃度,分析體格指標(biāo)及膳食脂肪與瘦素的關(guān)系。結(jié)果女性血清瘦素水平高于男性(P0.001)。BMI、WHtR與瘦素水平均呈正相關(guān),相關(guān)系數(shù)男性和女性分別為0.488、0.576和0.453、0.333(P0.0001)。調(diào)整WHtR后女性BMI與瘦素水平仍有相關(guān)性(r=0.321,P0.0001),調(diào)整BMI后男性WHtR與瘦素水平仍有相關(guān)性(r=0.354,P0.0001),其余指標(biāo)相關(guān)性消失。偏最小二乘回歸結(jié)果顯示男性WHtR(β=0.27)標(biāo)準(zhǔn)化偏回歸系數(shù)高于BMI(β=0.21),而女性則為BMI(β=0.26)高于WHtR(β=0.20)。男性總能量、總脂肪、單不飽和脂肪酸(MUFA)與瘦素水平呈負(fù)相關(guān)(P0.05),而女性多不飽和脂肪酸(PUFA)供能比及(PUFA+MUFA):SFA與瘦素水平呈正相關(guān)(P0.05)。對(duì)男性調(diào)整WHtR、對(duì)女性調(diào)整BMI,可見(jiàn)男性總脂肪、MUFA仍與瘦素呈負(fù)相關(guān)(P0.05);女性PUFA供能比與瘦素呈正相關(guān)(P0.05),其余指標(biāo)相關(guān)性消失。結(jié)論肥胖程度與瘦素水平呈正相關(guān)關(guān)系,在評(píng)價(jià)肥胖與瘦素水平關(guān)系時(shí),男性WHtR與瘦素水平相關(guān)性更強(qiáng),女性BMI與瘦素水平相關(guān)性更強(qiáng);男性總脂肪攝入量、MUFA與瘦素水平呈負(fù)相關(guān),女性PUFA供能比與瘦素水平呈正相關(guān)。
[Abstract]:Objective to analyze the correlation between body mass index (BMI), waist height ratio (WHtR), dietary fat intake and serum leptin level in middle-aged residents of Zhejiang Province. In December 2014, 513 subjects aged 30 to 65 years old from 4 districts and counties in Zhejiang Province were selected, and their height and weight were measured by a 3-day 24-hour diet review method. Results Serum leptin level in women was higher than that in men (P 0.001). BMIM WHtR was positively correlated with leptin levels. The correlation coefficient between male and female were 0. 488, 0. 576 and 0. 453, respectively. After adjusting for WHtR, there was still a correlation between BMI and leptin level in female patients (P 0.321, P 0.0001). There was still a correlation between WHtR and leptin level after adjusting BMI (P 0.0001). The results of partial least square regression showed that the standardized partial regression coefficient of WHtR (尾 + 0.27) was higher than that of BMI (尾 = 0.21). BMI0.26 in females was higher than that in WHTR0.200.The total energy and fat in men. Monounsaturated fatty acid (MUFAA) was negatively correlated with leptin level (P 0.05). The ratio of energy supply to energy of polyunsaturated fatty acid (PUFAA) and the level of leptin were positively correlated with the ratio of MUFA):SFA to leptin in women (P 0.05). WHtR was adjusted for men. For women adjusting for BMIs, there was a negative correlation between total fat MUFA and leptin in male patients (P 0.05). There was a positive correlation between the energy supply ratio of PUFA and leptin and the correlation between leptin and other indexes. Conclusion there is a positive correlation between the degree of obesity and the level of leptin, and in the evaluation of the relationship between obesity and leptin level. The correlation between WHtR and leptin level was stronger in male and BMI and leptin level in female. There was a negative correlation between total fat intake and leptin level in men, and a positive correlation between PUFA energy supply ratio and leptin level in women.
【作者單位】： 中國(guó)疾病預(yù)防控制中心營(yíng)養(yǎng)與健康所衛(wèi)生計(jì)生委微量元素重點(diǎn)實(shí)驗(yàn)室;浙江省疾病預(yù)防控制中心;
【基金】：國(guó)家自然科學(xué)基金(No.81372992)
【分類號(hào)】：R151.42
【正文快照】： 瘦素為脂肪細(xì)胞中分泌的一種蛋白質(zhì),可調(diào)節(jié)機(jī)體內(nèi)能量平衡,減少能量攝入并增加能量消耗[1],但肥胖個(gè)體常出現(xiàn)瘦素抵抗,血清瘦素濃度反而上升,這可能是肥胖產(chǎn)生的機(jī)制之一[2]。目前國(guó)內(nèi)外關(guān)于肥胖與瘦素相關(guān)性的研究多將體質(zhì)指數(shù)(body mass index,BMI)作為肥胖指標(biāo)進(jìn)行分析和調(diào)

【相似文獻(xiàn)】

相關(guān)期刊論文 前10條

1 侯英;杜馥曼;滕海坤;楊玉芝;;彌漫性毒性甲狀腺腫患者瘦素水平及臨床意義[J];放射免疫學(xué)雜志;2008年01期

2 郭子義,席煥久;青春期瘦素水平及其影響因素的研究[J];錦州醫(yī)學(xué)院學(xué)報(bào);2004年04期

3 程瑞迎;秦潔;胡玲;康文娟;董進(jìn);;老年糖尿病視網(wǎng)膜病變瘦素水平與頸動(dòng)脈內(nèi)中膜厚度的相關(guān)性[J];中國(guó)藥物與臨床;2008年12期

4 許倩,許建娟;妊娠婦女瘦素水平測(cè)定及其臨床意義[J];中國(guó)優(yōu)生與遺傳雜志;2002年03期

5 謝維衛(wèi);妊娠期肝內(nèi)膽汁淤積癥的瘦素水平[J];中國(guó)優(yōu)生與遺傳雜志;2005年07期

6 王彥德,孫袁,劉虹,張志萍,周紅,劉英;妊娠期肝內(nèi)膽汁淤積癥患者瘦素水平檢測(cè)的臨床意義[J];檢驗(yàn)醫(yī)學(xué);2005年01期

7 翁翠萍;;慢性阻塞性肺疾病患者瘦素水平的臨床檢測(cè)分析[J];中華全科醫(yī)學(xué);2009年04期

8 徐海霞;蔣紅雨;;瘦素水平在原發(fā)性腎病綜合征激素治療中的意義[J];貴陽(yáng)醫(yī)學(xué)院學(xué)報(bào);2010年01期

9 黃蓉,黃席珍,王惠閣,黎明,肖毅;經(jīng)鼻持續(xù)氣道內(nèi)正壓通氣治療對(duì)阻塞性睡眠呼吸暫停低通氣綜合征瘦素水平及代謝紊亂的影響[J];中國(guó)醫(yī)學(xué)科學(xué)院學(xué)報(bào);2004年02期

10 王彥德,孫袁,劉虹,張志萍,魯力,周紅;妊娠高血壓綜合征患者瘦素水平的檢測(cè)及臨床意義[J];現(xiàn)代檢驗(yàn)醫(yī)學(xué)雜志;2004年02期

相關(guān)會(huì)議論文 前10條

1 杜堅(jiān)宗;欽光躍;黃R投，

本文編號(hào)：1437707