【摘要】： 目的:ASNR為重度感音性聾耳在強聲刺激下出現(xiàn)的誘發(fā)電位,在電生理學(xué)方面已驗證其與VEMP同起源于球囊,而與聽力和冰水試驗結(jié)果無關(guān),為腦干水平前庭源性電位。本研究擬通過對正常人耳進行噪聲掩蔽,消除聽覺成分(ABR波)的出現(xiàn),在強聲刺激下誘發(fā)出現(xiàn)短潛伏期負電位ASNR。 方法:對20個正常人(志愿者)分別進行氣導(dǎo)VEMP短聲刺激,記錄下VEMP的出現(xiàn)率、潛伏期,再測試掩蔽后的VEMP出現(xiàn)率;進行氣導(dǎo)ABR測試,記錄ABR波,再通過氣導(dǎo)強聲刺激,骨導(dǎo)噪聲掩蔽,誘發(fā)ASNR波出現(xiàn),探討ASNR波的出現(xiàn)率、潛伏期。 結(jié)果:20個正常人(40耳)中12耳出現(xiàn)ASNR,出現(xiàn)率為30%,其閾值范圍為85-105dB nHL,平均為97.5±5.24 dB nHL,掩蔽噪聲閾值范圍為70-90dB nHL ,平均為81.67±7.53dB nHL,潛伏期范圍2.72-3.36ms(平均為3.11±0.15ms),閾值平均潛伏期3.02±0.16ms。做VEMP測試時,氣導(dǎo)短聲刺激加骨導(dǎo)噪聲掩蔽40耳有19耳誘發(fā)出p13和n23波,出現(xiàn)率為47.5%,其p13潛伏期范圍為11.92-14.15ms,平均為12.81±0.83ms,n23潛伏期范圍18.98-22.19ms,平均為20.52±0.89ms。 結(jié)論:根據(jù)ASNR波的出現(xiàn)依賴于正常的球囊功能,在重度感音神經(jīng)性聾患者中,ASNR的出現(xiàn)已經(jīng)被證實。本實驗應(yīng)用骨導(dǎo)耳機發(fā)出噪聲掩蔽模擬感音神經(jīng)性聾,由氣導(dǎo)耳機高強度聲刺激成功誘發(fā)出ASNR波形。證明ASNR不僅出現(xiàn)在重度耳聾的患者,在正常人耳中同樣可以引出。
[Abstract]:Aim: ASNR is a kind of evoked potential of severe sensorineural deafness under intense sound stimulation. It has been proved in electrophysiology that it originated from balloon with VEMP, but not with the results of hearing and ice water test. It is a vestibular potential at brainstem level. The aim of this study is to eliminate the appearance of auditory components (ABR wave) by noise masking in normal human ears, and to induce short latency negative potentials (ASNR.) under intense sound stimulation. Methods: 20 normal subjects (volunteers) were subjected to short sound stimulation with air conduction VEMP. The occurrence rate and latency of VEMP were recorded, and then the VEMP occurrence rate after masking was tested. The ABR wave was recorded by ABR test, and then the occurrence rate and latency of ASNR wave were discussed. The ASNR wave was induced by strong acoustic stimulation, bone conduction noise masking, and the occurrence rate and latency of ASNR wave were discussed. Results: the occurrence rate of ASNR, was 30% in 12 ears of 20 normal subjects (40 ears). The threshold range of 85-105dB nHL, was 97.5 鹵5.24 dB nHL, the masking noise threshold was 81.67 鹵7.53dB nHL, in 70-90dB nHL,. The range of latency was 2.72-3.36ms (mean 3.11 鹵0.15ms), and the mean threshold latency was 3.02 鹵0.16ms. During the VEMP test, 19 ears (47.5%) induced p13 and n23 waves in 40 ears with air conduction short sound stimulation and bone conduction noise masking. The latency range of p13 was 11.92 鹵14.15 Ms (average 12.81 鹵0.83 Ms), and the latency range of p13 was 11.92 渭 14.15 Ms (mean, 12.81 鹵0.83 Ms) in 19 ears (47.5%). The n23 incubation period ranged from 18.98 to 22.19 Ms, with an average of 20.52 鹵0.89 Ms. Conclusion: according to the appearance of ASNR wave depends on the normal balloon function, the appearance of ASNR has been confirmed in patients with severe sensorineural deafness. In this study, bone-guided headphones were used to masking simulated sensorineural deafness, and ASNR waveforms were successfully induced by high-intensity acoustic stimulation of air-guided headphones. It is concluded that ASNR is not only present in patients with severe deafness, but also can be induced in normal human ears.
【學(xué)位授予單位】：廣西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2010
【分類號】：R764

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相關(guān)期刊論文 前1條

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