【摘要】：目的探討失匹配負波(mismatch negativity,MMN)檢查在正常青年人中的特點,并分析閱讀狀態(tài)和集中注意力時MMN檢查的結(jié)果有無差異。方法對12例青年女性(年齡29-31y,平均30.08y)和18例青年男性(年齡27-34y,平均30.22y)行MMN檢查,所有受試者均行聽性腦干反應(ABR)閾值檢查,確定ABR閾值,MMN檢查在受試者在閱讀狀態(tài)和集中注意力狀態(tài)時分別檢測,采用oddball刺激方式,給予短純音刺激,偏差刺激聲為2000Hz,概率為20%,標準刺激為1000 Hz,概率為80%,刺激頻率為1.1次/s,刺激聲強度為ABR閾上50dB nHL;觀察MMN潛伏期及波幅的特點。結(jié)果所有受試者ABR閾值均≤25 dB nHL。每例受試者均可引出MMN波形,女性在閱讀狀態(tài)下MMN潛伏期為159.57±20.64 ms,波幅為3.82±1.38 uV,在集中注意力狀態(tài)下MMN潛伏期為155.96±17.51 ms,波幅為4.28±1.89 uV,經(jīng)配對t檢驗潛伏期和波幅在兩種狀態(tài)下無顯著差異;男性在閱讀狀態(tài)下MMN潛伏期為150.48±19.57 ms,波幅為3.75±1.27 uV,在集中注意力狀態(tài)下MMN潛伏期為144.81±15.42 ms,波幅為3.99±1.34 uV,經(jīng)配對t檢驗潛伏期和波幅在兩種狀態(tài)下無顯著差異;經(jīng)獨立樣本t檢驗,男女在上述兩種狀態(tài)下MMN波幅和潛伏期均無顯著差異。結(jié)論正常青年男女均能引出MMN波形,男女之間MMN檢查的波幅和潛伏期無差異,閱讀狀態(tài)和集中注意力狀態(tài)對MMN檢查的波幅和潛伏期無影響。
[Abstract]:Objective to investigate the characteristics of mismatched negative wave (mismatch negativity,MMN) examination in normal young people and to analyze the differences between the results of MMN examination and that of reading state and concentration. Methods MMN was performed in 12 young women (age 29-31 yy, mean 30.08y) and 18 young men (age 27-34 yy, mean 30.22 y). All subjects were examined with (ABR) threshold of auditory brainstem response and ABR threshold was determined. MMN was used to test the subjects' reading state and concentration state respectively. They were given short tone stimulation by oddball stimulation, the bias stimulus was 2000Hz, the probability was 20 and the standard stimulus was 1000 Hz,. The frequency of stimulation is 1.1 times / s, and the sound intensity of stimulus is ABR suprathreshold 50dB nHL;. The latency and amplitude of MMN were observed. Results the ABR threshold of all subjects was 鈮，

本文編號：2375684