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高度近視合并白內(nèi)障植入不同人工晶狀體的臨床分析

發(fā)布時(shí)間:2018-11-06 11:28
【摘要】:一、高度近視合并白內(nèi)障植入三種不同人工晶狀體的臨床分析 目的:比較高度近視合并白內(nèi)障超聲乳化吸除分別植入3種不同人工晶狀體(intraocular lens IOL)的臨床效果。 方法:回顧性系列病例研究;仡櫺苑治鎏旖蚴醒劭漆t(yī)院白內(nèi)障中心2008年5月至2009年6月高度近視合并白內(nèi)障患者68眼行超聲乳化白內(nèi)障吸除聯(lián)合IOL植入術(shù)后3mo的隨訪資料;颊叻謩e植入一片式三襻親水性丙烯酸酯IOL(Bigbag, ZEISS)、一片式C形襻親水性丙烯酸酯IOL(620H, Rayner),一片式C形襻親水性丙烯酸酯IOL (HQ201-hep)。使用Pentacam三維眼前節(jié)測(cè)量系統(tǒng)采集各眼Scheimpflug圖像,測(cè)量散瞳后前房深度,使用Image-pro plus 6.0圖像分析得出IOL的傾斜度和偏心值。使用iTrace視覺分析儀測(cè)量5mm瞳孔直徑下的眼內(nèi)球差。檢測(cè)術(shù)后IOL眼實(shí)際屈光度與靶屈光度差異。滿足正態(tài)分布和方差齊性的行單因素方差分析,采用SNK-q檢驗(yàn)進(jìn)行組間兩兩比較。結(jié)果:3組間前房深度比較有統(tǒng)計(jì)學(xué)意義(F=50.74,P0.05)。實(shí)際屈光度與靶屈光度的誤差,3組比較無統(tǒng)計(jì)學(xué)意義(F=1.391,P0.05)。IOL偏心與傾斜在水平和垂直方向上的數(shù)值差異均無統(tǒng)計(jì)學(xué)意義(P0.05)。3組間5mm瞳孔直徑下眼內(nèi)球差比較無統(tǒng)計(jì)學(xué)意義(F=2.096,P0.05)。未見后囊膜混濁,黃斑水腫,視網(wǎng)膜脫離發(fā)生。 結(jié)論:3種不同IOL均可用于高度近視合并白內(nèi)障患者,但各有其優(yōu)越性和局限性。 二、高度近視合并白內(nèi)障植入不同多焦點(diǎn)人工晶狀體視覺質(zhì)量分析 目的:比較高度近視合并白內(nèi)障超聲乳化吸除分別植入2種不同多焦點(diǎn)人工晶狀體(multifocal intraocular lens, MIOL)的視覺質(zhì)量。 方法:回顧性系列病例研究;仡櫺苑治鎏旖蚴醒劭漆t(yī)院白內(nèi)障中心2009年2月至2010年6月高度近視合并白內(nèi)障40眼行超聲乳化白內(nèi)障吸除聯(lián)合IOL植入術(shù)后3mo的隨訪資料;颊叻謩e植入AR40e(SENSAR, AMO)單焦點(diǎn)IOL(monofocal/single-focal intraocular lens, SIOL) 20眼、REZOOM (NXG1, AMO)折射型MIOL8眼, TECNIS ZMA00 (AMO)衍射型MIOL12眼。使用Snellen標(biāo)準(zhǔn)視力表(5m)及Colenbrander Mixed Contrast Card Set視力測(cè)試卡(0.4m)分別測(cè)量裸眼遠(yuǎn)近視力,最佳矯正遠(yuǎn)視力及最佳矯正遠(yuǎn)視力下近視力。使用iTrace波前像差儀測(cè)量5mm瞳孔直徑下的眼內(nèi)像差及調(diào)制傳遞函數(shù)(modulationtransfer function, MTF)曲線。滿足正態(tài)分布和方差齊性的行單因素方差分析,采用SNK-q檢驗(yàn)進(jìn)行組間兩兩比較。不滿足的行K-W秩和檢驗(yàn)。 結(jié)果:3組患者術(shù)后3個(gè)月裸眼遠(yuǎn)視力,最佳矯正遠(yuǎn)視力下近視力比較有統(tǒng)計(jì)學(xué)意義(P0.05)。裸眼近視力,最佳矯正遠(yuǎn)視力差異無統(tǒng)計(jì)學(xué)意義(P0.05)。3組患者在瞳孔5mm直徑時(shí),眼內(nèi)球差差異有統(tǒng)計(jì)學(xué)意義(P0.05),眼內(nèi)彗差及三葉草比較無統(tǒng)計(jì)學(xué)意義(p0.05)。MTF值在5/10/15cpd時(shí)差異有統(tǒng)計(jì)學(xué)意義(p0.05)。 結(jié)論:高度近視合并白內(nèi)障患者更適合植入衍射型MIOL。
[Abstract]:1. Clinical analysis of three different kinds of intraocular lens implantation in high myopia with cataract objective: to compare the clinical effects of phacoemulsification and implantation of three different intraocular lens (intraocular lens IOL) in high myopia with cataract. Methods: a series of retrospective case studies. The follow-up data of 68 eyes of patients with high myopia and cataract after phacoemulsification combined with IOL implantation in Tianjin Eye Hospital from May 2008 to June 2009 were analyzed retrospectively. Patients were implanted with a three-loop hydrophilic acrylate (IOL (Bigbag, ZEISS),) and a C-shaped loop (IOL) (620H, Rayner), / C) IOL (HQ201-hep). The Pentacam 3D anterior segment measurement system was used to collect the Scheimpflug images of each eye, and the anterior chamber depth after pupil dilation was measured. The tilt and eccentricity of IOL were obtained by Image-pro plus 6.0 image analysis. ITrace visual analyzer was used to measure the intraocular spherical aberration under the pupil diameter of 5mm. The difference between the actual diopter and target diopter of IOL eyes after operation was detected. Univariate ANOVA satisfying normal distribution and homogeneity of variance was performed, and SNK-q test was used to compare the two groups. Results: there was significant difference in anterior chamber depth among the three groups (P 0.05). There was no significant difference between the actual diopter and target diopter in the three groups (F = 1.391, P < 0.05). There was no significant difference between). IOL eccentricity and tilt in horizontal and vertical direction (P0.05). There was no significant difference in intraocular spherical aberration under the pupil diameter of 5mm among the three groups (FF2.096). No posterior capsule opacification, macular edema, retinal detachment occurred. Conclusion: three kinds of IOL can be used in high myopia patients with cataract, but each has its advantages and limitations. Visual quality Analysis of different Multi-focus IOL implantation in High myopia with Cataract objective: to compare the phacoemulsification and implantation of two kinds of multi-focus intraocular lens (multifocal intraocular lens,) in high myopia with cataract implantation. MIOL) visual quality. Methods: a series of retrospective case studies. The follow-up data of 40 eyes with high myopia combined with cataract after phacoemulsification and IOL implantation in Tianjin Eye Hospital from February 2009 to June 2010 were analyzed retrospectively. AR40e (SENSAR, AMO) single focus IOL (monofocal/single-focal intraocular lens, SIOL) 20 eyes) refracted MIOL8 eyes and TECNIS ZMA00 (AMO) diffractive MIOL12 eyes were implanted respectively. Snellen standard visual acuity chart (5m) and Colenbrander Mixed Contrast Card Set visual acuity test card (0.4m) were used to measure the uncorrected far and near visual acuity, the best corrected far visual acuity and the best corrected far visual acuity. The intraocular aberration and modulation transfer function (modulationtransfer function, MTF) curves of 5mm pupil diameter were measured by iTrace wavefront aberration instrument. Univariate ANOVA satisfying normal distribution and homogeneity of variance was performed, and SNK-q test was used to compare the two groups. Dissatisfied with the K-W rank sum test. Results: three months after operation, the uncorrected distant visual acuity and the near visual acuity under the best corrected distant visual acuity were statistically significant (P0.05). There was no significant difference in uncorrected near visual acuity and best corrected far visual acuity (P0.05). There were significant differences in intraocular spherical aberration in pupil 5mm diameter in 3 groups (P0.05). There was no significant difference in intraocular coma and clover (p0. 05). MTF in 5/10/15cpd). Conclusion: high myopia with cataract is more suitable for the implantation of diffractive MIOL..
【學(xué)位授予單位】:天津醫(yī)科大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2011
【分類號(hào)】:R779.66

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