發(fā)布時(shí)間：2018-07-03 05:39

  本文選題：阻塞性睡眠呼吸暫停綜合征 + 體質(zhì)量指數(shù)��； 參考：《中華高血壓雜志》2014年07期

【摘要】：目的了解非肥胖阻塞性睡眠呼吸暫停綜合征(OSAS)患者睡眠監(jiān)測(cè)參數(shù)、血壓、血脂水平及其風(fēng)險(xiǎn)因素。方法連續(xù)入選2009年1月至2010年12月新疆維吾爾自治區(qū)人民醫(yī)院睡眠中心及高血壓中心就診的非肥胖高血壓患者221例,均行多導(dǎo)聯(lián)睡眠監(jiān)測(cè),比較無(wú)OSAS組(n=87)和合并OSAS組(n=134)患者睡眠參數(shù)、血壓及代謝指標(biāo),Logistic回歸分析OSAS的危險(xiǎn)因素。結(jié)果合并OSAS組年齡[(51.1±11.1)比(43.9±12.6)歲]、頸圍[(36.8±3.1)比(35.5±3.0)cm]、呼吸暫停低通氣指數(shù)[(14.3比1.3)次/h]、阻塞平均持續(xù)時(shí)間[(19.9±13.0)比(6.3±8.4)min]、低密度脂蛋白膽固醇(LDL-C)[(2.6±0.8)比(2.3±0.7)mmol/L]明顯高于無(wú)OSAS組,而白天、夜間及24h平均心率均明顯低于無(wú)OSAS組(均P0.05)。多因素Logistic回歸分析顯示,頸圍和年齡為非肥胖高血壓人群患OSAS的危險(xiǎn)因素,其中,頸圍≥38cm者患OSAS風(fēng)險(xiǎn)是頸圍32cm者的5.97倍(95%CI1.61~22.09),年齡≥65歲者患OSAS風(fēng)險(xiǎn)是年齡35歲者的7.56倍(95%CI1.13~50.52)。結(jié)論合并OSAS患者比無(wú)OSAS者LDL-C增高,而平均心率減慢。頸圍和年齡是非肥胖高血壓人群患OSAS的危險(xiǎn)因素。
[Abstract]:Objective to investigate sleep monitoring parameters, blood pressure, blood lipids and risk factors in non-obese patients with obstructive sleep apnea syndrome (OSAS). Methods from January 2009 to December 2010, 221 non-obese hypertensive patients were selected from sleep center and hypertension center of Xinjiang Uygur Autonomous region people's Hospital. The sleep parameters, blood pressure and metabolic parameters of patients without OSAS (nong87) and with OSAS (nang134) were compared. Logistic regression analysis was performed on the risk factors of OSAS. Results the age [(51.1 鹵11.1) vs (43.9 鹵12.6) years], neck circumference [(36.8 鹵3.1) vs (35.5 鹵3.0) cm], apnea hypopnea index [(14.3 vs 1.3) times / h], mean duration of obstruction [(19.9 鹵13.0) vs (6.3 鹵8.4) min], low density lipoprotein cholesterol (LDL-C) [(2.6 鹵0.8) vs (2.3 鹵0.7) mmol / L] in the combined OSAS group were significantly higher than those in the non-OSAS group. The mean heart rate at night and 24 h was significantly lower than that in OSAS group (P 0.05). Multivariate logistic regression analysis showed that neck circumference and age were the risk factors of OSAS in non-obese hypertensive population. The risk of OSAS in patients with neck circumference 鈮，

本文編號(hào)：2092604