大連眼科門診眼干澀患者調(diào)查
發(fā)布時間:2018-06-23 19:28
本文選題:干眼 + 患病率; 參考:《大連醫(yī)科大學(xué)》2011年碩士論文
【摘要】:目的: 調(diào)查大連醫(yī)科大學(xué)眼科門診眼干澀患者干眼的患病情況,統(tǒng)計分析大連地區(qū)干眼的誘因、癥狀、體征及臨床檢查結(jié)果,進一步提高對干眼的認識。 方法: 隨機抽取2010年11月1日至2010年12月30日來大連醫(yī)科大學(xué)附一院眼科門診就診的有眼干澀主訴的235名患者(470只眼),分為7個年齡組,并先進行問卷調(diào)查,再進行裂隙燈檢查,淚膜破裂時間測定,淚湖彎月面檢查,角膜熒光素鈉染色,淚液分泌實驗。對調(diào)查所得數(shù)據(jù)用SPSS17.0軟件進行統(tǒng)計分析。 結(jié)果: 本次共調(diào)查235人(470只眼),調(diào)查患者的平均年齡48.55±15.77歲。女性共調(diào)查158人,占67.23%,男性共調(diào)查77人,占32.76%,男女比為1:2.05。男女組人數(shù)調(diào)查結(jié)果進行配對t檢驗,t=-3.859,p=0.008,p0.05,本次調(diào)查男女人數(shù)有顯著性差異。我院眼科門診有眼干澀主訴患者干眼癥患病率為45.10%,干眼病患病率為50.63%,干眼綜合征患病率為4.25%,男性患病率32.76%女性患病率67.23%,男女患病率比較用卡方分析結(jié)果x2=20.687,p0.05,男女患病率有顯著性差異。女性患病率明顯高于男性。在調(diào)查的470只眼中BUT≤5s的為236只,占50.21%,BUT在6—10s的為167只,占35.53%,本次調(diào)查有85.74%的眼干澀主訴患者有淚膜不穩(wěn)定;在Schirmer’s I試驗中有373只眼≤10mm/5min,占79.36% ,有角膜染色的為207只眼,占44.04%,淚湖彎月面檢查有412只眼異常,占87.65%。男女干眼患病時間用配對t檢驗t=-0.223,p=0.831,p0.05,無顯著性差異。對各年齡組干眼患病時間與干眼人數(shù)用相關(guān)分析結(jié)果為Pearson相關(guān)性:-0.301,顯著性(雙側(cè)):p0.05,干眼與患病時間無相關(guān)性。本次調(diào)查內(nèi)容中主觀癥狀出現(xiàn)頻次由多到少依次為:眼干澀眼疲勞眼癢異物感眼痛頭痛喉嚨干嘴干視物模糊眼紅流淚燒灼感有粘液分泌物。調(diào)查內(nèi)容中不良生活習(xí)慣出現(xiàn)的頻次由多到少依次為:長期用暖氣長期用電腦女性眼部美容長時間駕車長時間用空調(diào)吸煙失眠。干眼與角膜染色、BUT測定、淚湖彎月面檢查、schirmerⅠ實驗用相關(guān)分析結(jié)果均相關(guān),干眼與BUT測定、schirmer’sⅠ實驗在0.01水平上顯著相關(guān);與角膜染色與淚湖彎月面檢查在0.05水平上顯著相關(guān);各干眼檢查結(jié)果均顯著相關(guān)。干眼與本次調(diào)查內(nèi)容中的不良生活習(xí)慣、不同職業(yè)及各主觀癥狀用相關(guān)分析結(jié)果均有顯著的相關(guān)性,其相互之間均顯著相關(guān)。 結(jié)論: 1、我院眼科門診有眼干澀主訴患者干眼癥患病率為45.10%,干眼病患病率為50.63%,干眼綜合征患病率為4.25%,男性患病率32.76%女性患病率67.23%,女性患病率明顯高于男性。 2、干眼發(fā)病與年齡、性別、絕經(jīng)、職業(yè)、長期使用眼藥水、空調(diào)、暖氣、電腦均相關(guān)。 3、本次調(diào)查結(jié)果中主觀癥狀出現(xiàn)頻次由多到少依次為:眼干澀、眼疲勞、眼癢、異物感、眼痛、頭痛、喉嚨干嘴干、視物模糊、眼紅、流淚、燒灼感、有粘液分泌物。 4、我院眼科門診有眼干澀主訴患者最后診斷以干眼病為主。
[Abstract]:Objective: to investigate the incidence of dry eye in ophthalmological outpatient department of Dalian Medical University, and analyze the inducement, symptom, sign and clinical examination result of dry eye in Dalian area, so as to improve the understanding of dry eye. Methods: from November 1, 2010 to December 30, 2010, 235 patients (470 eyes) with dry eye complaints were randomly selected and divided into 7 age groups. Slit-lamp examination, lacrimal film rupture time measurement, lacrimal lake meniscus examination, corneal fluorescein sodium staining, tear secretion test. The data were analyzed by SPSS 17.0 software. Results: 235 patients (470 eyes) were investigated. The average age of the patients was 48.55 鹵15.77 years old. A total of 158 women (67.23%) and 77 men (32.76%) were surveyed, with a ratio of 1: 2.05. The number of male and female groups was tested by paired t test (t = -3.859), and there was a significant difference in the number of male and female population in this survey. The prevalence rate of xerophthalmia, dry eye syndrome and dry eye syndrome were 45.10, 50.63 and 4.25, respectively. The prevalence rate of male was 32.76%. The prevalence rate of female and male was 67.233.The results of chi-square analysis were used to compare the prevalence of male and female by chi-square analysis. There was significant difference in the rate of disease. The prevalence rate of female was significantly higher than that of male. In 470 eyes of the survey, the number of patients with but 鈮,
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