本文選題：小兒喉乳頭狀瘤 + 發(fā)病年齡��； 參考：《廣西醫(yī)科大學(xué)》2010年碩士論文

【摘要】： 目的：回顧性分析小兒喉乳頭狀瘤的臨床特征,探索可能影響其臨床行為的因素；了解喉乳頭狀瘤患兒的HPV感染情況及其與臨床特征的關(guān)系。 方法：收集廣西醫(yī)科大學(xué)第一附屬醫(yī)院耳鼻咽喉頭頸外科1989.1.1-2009.10.31收治的112例小兒喉乳頭狀瘤患者的病歷資料,包括性別、發(fā)病年齡、起病癥狀、確診時(shí)間、入院主訴、手術(shù)方式、病灶部位、是否行氣管切開、HPV檢測結(jié)果等,記錄患者手術(shù)次數(shù)、手術(shù)間隔時(shí)間、術(shù)后輔助治療等情況。分析患兒性別、HPV感染、氣管切開、氣管內(nèi)腫瘤、發(fā)病年齡、手術(shù)次數(shù)、手術(shù)頻率之間的關(guān)系。 結(jié)果：共收集112例患者資料,分組統(tǒng)計(jì)發(fā)現(xiàn)男性患兒組和女性患兒組的HPV感染率、氣管切開率、氣管內(nèi)腫瘤發(fā)生率、發(fā)病年齡及手術(shù)頻率的差異無顯著意義。HPV陽性組和HPV陰性組的氣管切開率、氣管內(nèi)腫瘤發(fā)生率無統(tǒng)計(jì)學(xué)差異,HPV陽性組的發(fā)病年齡小于HPV陰性組(p=0.05),HPV陽性組的手術(shù)頻率高于HPV陰性組(p=0.000)。發(fā)病年齡≤2歲組的氣管切開率、氣管內(nèi)腫瘤發(fā)生率高于發(fā)病年齡2歲組p=0.039,0.004),患兒手術(shù)頻率與其發(fā)病年齡無明顯關(guān)系。氣管切開組的手術(shù)次數(shù)高于未氣管切開組(p=0.000),但兩者氣管內(nèi)腫瘤發(fā)生率的差異無顯著性。氣管內(nèi)有腫瘤組的手術(shù)次數(shù)高于氣管內(nèi)無腫瘤組(p=0.000)。患兒的HPV感染率為63.2％。 結(jié)論：1.發(fā)病年齡≤2歲的喉乳頭狀瘤患兒有更高的氣管切開率和氣管內(nèi)乳頭狀瘤發(fā)生率。2.氣管切開與發(fā)生氣管內(nèi)乳頭狀瘤無明顯關(guān)系。3.HPV感染的患兒發(fā)病年齡較小,手術(shù)頻率較高。
[Abstract]:Objective: to retrospectively analyze the clinical features of laryngeal papilloma in children, explore the factors that may affect its clinical behavior, and understand the infection of HPV in children with laryngeal papilloma and its relationship with clinical features. Methods: the medical records of 112 pediatric patients with laryngeal papilloma admitted to the Department of Otorhinolaryngology and head and neck surgery in the first affiliated Hospital of Guangxi Medical University were collected, including sex, age of onset, onset symptoms, time of diagnosis, admission to hospital and operation methods. The location of the lesion, whether the tracheotomy or HPV test results, recorded the number of operations, surgical interval, postoperative adjuvant treatment and so on. The relationship among sex HPV infection, tracheotomy, intratracheal tumor, age of onset, times of operation and frequency of operation were analyzed. Results: the data of 112 patients were collected. The HPV infection rate, tracheotomy rate and intratracheal tumor rate were found in male and female groups. There was no significant difference in age of onset and frequency of operation. Tracheotomy rate in HPV-positive group and HPV negative group was not significant. There was no significant difference in the incidence of intratracheal neoplasms. The age of onset in HPV-positive group was lower than that in HPV negative group. The frequency of operation in HPV-positive group was higher than that in HPV negative group. The rate of tracheotomy was higher in the age 鈮，

本文編號：1991418