本文選題：鼻腔 + 鼻竇炎��； 參考：《吉林大學(xué)》2010年碩士論文

【摘要】： 鼻腔結(jié)構(gòu)的任何細(xì)微變化都會導(dǎo)致通過鼻腔的氣流發(fā)生一系列相應(yīng)的變化如氣體流量、壓強(qiáng)等數(shù)據(jù)的改變,這有可能導(dǎo)致諸如慢性鼻-鼻竇炎等鼻科疾病,對鼻腔氣流流場的深入研究有利于進(jìn)一步認(rèn)識鼻腔結(jié)構(gòu)與功能之間的關(guān)系。目前而言自奧地利學(xué)者M(jìn)esserklinger開創(chuàng)了鼻內(nèi)窺鏡鼻竇外科手術(shù)的新領(lǐng)域以來,鼻竇外科取得了革命性進(jìn)步,并逐步發(fā)展成為功能性內(nèi)窺鏡鼻竇外科。長期以來有許多學(xué)者對鼻竇炎進(jìn)行了大量的研究證實(shí)了諸如感染因素、變態(tài)反應(yīng)因素、纖毛引流等其他因素的影響,但手術(shù)后由于鼻腔內(nèi)部結(jié)構(gòu)改變而引發(fā)鼻腔氣流力學(xué)的變化仍卻一直缺乏足夠的認(rèn)識。這是因?yàn)殚L期以來,對于鼻腔氣體動力學(xué)的研究一直處于初級階段。上世紀(jì)八十年代,人們主要通過制作各種材質(zhì)的等比例或放大比例的鼻腔尸源性實(shí)體模型,并向模型中注入各種形式的含有示蹤成分的流體來觀察鼻腔氣流場。進(jìn)入九十年代后則是應(yīng)用影像學(xué)數(shù)據(jù)構(gòu)建模型,并以此為基礎(chǔ)應(yīng)用高性能計(jì)算機(jī)和現(xiàn)代大型流體分析商業(yè)軟件進(jìn)一步研究人體生理狀態(tài)下鼻腔內(nèi)流流場變化。 但是受制于早期模型制備工藝的粗糙以及CT、MRI等檢查設(shè)備的分辨率限制和信號損失,以上這些方法不能準(zhǔn)確的反應(yīng)鼻腔氣流場的真實(shí)情況,故本文旨在于利用人體尸頭標(biāo)本結(jié)合高靈敏度的微型電子測量元件反映出鼻腔氣流場的真實(shí)情況。并希望可以通過該研究進(jìn)一步改進(jìn)手術(shù)方式,臨床治療的效果。
[Abstract]:Any slight change in the structure of the nasal cavity will result in a series of corresponding changes in the airflow through the nasal cavity, such as changes in gas flow, pressure, etc., which may lead to nasal diseases such as chronic rhinosinusitis. The further study on the flow field of nasal cavity is helpful to further understand the relationship between the structure and function of nasal cavity. At present, since Austrian scholar Messerklinger initiated a new field of endoscopic sinus surgery, sinus surgery has made revolutionary progress, and gradually developed into functional endoscopic sinus surgery. For a long time, many scholars have done a lot of research on sinusitis to confirm the influence of other factors, such as infection factors, allergy factors, cilia drainage and so on. However, the change of airflow mechanics of nasal cavity caused by the change of nasal cavity structure after operation is still lack of enough understanding. This is because the study of nasal aerodynamics has been in its infancy for a long time. In the eighties of the last century, the nasal cavity airflow field was observed mainly by making the nasal cavity cadaveric solid model with equal proportion or magnification ratio of various materials, and injecting various kinds of fluid with tracer components into the model. In the 1990s, the imaging data were used to build the model, and based on it, the changes of the flow field in the nasal cavity under the physiological state of the human body were further studied by using the high performance computer and the modern large-scale fluid analysis commercial software. However, these methods can not accurately reflect the true situation of the nasal airflow field because of the roughness of the early model preparation process and the resolution limitation and signal loss of the equipment such as CTT / MRI. Therefore, the purpose of this paper is to reflect the real situation of the nasal airflow field by using the human cadaveric head specimen and the high sensitivity micro electronic measuring element. We also hope that we can further improve the operation and clinical treatment through this study.
【學(xué)位授予單位】：吉林大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2010
【分類號】：R765.9

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本文編號：1991291