本文選題：高海拔 + 非顳動脈炎性前部缺血性視神經(jīng)病變��； 參考：《青海大學》2013年碩士論文

【摘要】：目的：探討高海拔地區(qū)非顳動脈炎性前部缺血性視神經(jīng)病變(NAION)的發(fā)病因素 與臨床的相關(guān)研究。 方法:2011年3月-2012年9月期間來我科門診就診，，并確診為NAION的住院患者納為病例組。并將同一時期來我院參加門診體檢并與病例組年齡、性別相匹配的人群作為對照組。 1).將納入對象的個人資料進行詳細登記。 2).對納入對象進行詳盡的眼科檢查。 3).對納入對象進行血壓監(jiān)測及血常規(guī)、血脂、血糖、血液流變學等化驗檢查,并將觀察指標詳細記錄； 結(jié)果：1).NAION組與對照組之間總膽固醇、HDL-脂蛋白、血常規(guī)無顯著性差異(P＞0.05)，而甘油三脂、血糖、血壓有顯著性差異(P＜0.05)，NAION組較高。 2).全血粘度高切、血漿粘度、全血還原粘度中切、紅細胞變形指數(shù)、血沉、血沉方程K值二組之間無顯著性差異(P＞0.05),而全血黏度中低切、紅細胞壓積、全血還原粘度高低切、紅細胞聚集指數(shù)有顯著性差異(P＜0.05),NAION組較高。 結(jié)論：1).高海拔地區(qū)NAION的發(fā)病因素不是單一的,是多因素相互作用的結(jié)結(jié)果。 2).高海拔低壓低氧等環(huán)境條件下，NAION的發(fā)病與人體微循環(huán)發(fā)生的一系列病理生理變化相關(guān)。 3).甘油三脂、血壓、血糖對高海拔地區(qū)NAION的發(fā)生具有統(tǒng)計學意義。 4).高血粘度是高海拔地區(qū)NAION的發(fā)生的危險因素。 5).加強高海拔地區(qū)人群對NAION的健康教育，提高其對NAION防治的認識。
[Abstract]:Objective: to investigate the risk factors of nontemporal inflammatory anterior ischemic optic neuropathy (NAION) in high altitude area. A clinical study. Methods: from March 2011 to September 2012, inpatients diagnosed as NAION were admitted to our outpatient clinic as the case group. At the same time, the people who came to our hospital to attend outpatient examination and matched the age and sex of the case group were taken as the control group. 1. Register the personal data of the object in detail. 2. A detailed ophthalmic examination was carried out on the subjects involved. Three. Blood pressure monitoring, blood routine, blood lipid, blood sugar, hemorheology and other laboratory tests were carried out, and the observation indexes were recorded in detail. Results there was no significant difference in blood routine between the two groups (P > 0.05), but there was significant difference in triglyceride, blood glucose and blood pressure between the two groups (P < 0.05). 2. There was no significant difference in whole blood viscosity, plasma viscosity, whole blood reductive viscosity, erythrocyte deformability index, erythrocyte sedimentation equation K value between the two groups (P > 0.05), but the whole blood viscosity was low shear, hematocrit, whole blood reductive viscosity high and low shear. There was significant difference in erythrocyte aggregation index (P < 0.05). Conclusion 1: 1. The pathogenesis of NAION in high altitude area is not single, it is the result of multi-factor interaction. 2. The pathogenesis of NAION is related to a series of pathophysiological changes of human microcirculation at high altitude, low pressure and hypoxia. Three. Triglyceride, blood pressure and blood sugar were statistically significant in the occurrence of NAION at high altitude. 4. High blood viscosity is the risk factor of NAION in high altitude area. Five. To strengthen the health education of NAION in high altitude area and to improve their understanding of NAION prevention and treatment.
【學位授予單位】：青海大學
【學位級別】：碩士
【學位授予年份】：2013
【分類號】：R774.6

【參考文獻】

相關(guān)期刊論文 前10條

1 張超;李金科;唐紅;賈麗;;前部缺血性視神經(jīng)病變與頸動脈狹窄的相關(guān)性研究[J];國際眼科雜志;2011年03期

2 王小東;王彤;張德秀;;非動脈炎性前部缺血性視神經(jīng)病變與腹型肥胖的相關(guān)性研究[J];國際眼科雜志;2011年08期

3 律鵬 ,張文芳;高原眼病[J];高原醫(yī)學雜志;2004年02期

4 陳延君;張生林;王亞明;馮德君;姚毅章;;高原地區(qū)人員眼底改變與血壓、血脂及心電圖的關(guān)系[J];高原醫(yī)學雜志;2009年01期

5 蘇曉靈;周白麗;王嶸;常榮;;高原不同海拔地區(qū)高脂血癥患者血脂及血液流變學相關(guān)性研究[J];高原醫(yī)學雜志;2009年04期

6 張蓉;馬雪英;李凌;;高原地區(qū)前部缺血性視神經(jīng)病變臨床分析[J];高原醫(yī)學雜志;2011年03期

7 武莉莉;;糖尿病視網(wǎng)膜病變合并前部缺血性視神經(jīng)病變眼底血管造影特征[J];北京醫(yī)學;2012年11期

8 王建民,馬景學,王長齡,李素芬,史豐,楊愛琴;非動脈炎性前部缺血性視神經(jīng)病變的血流動力學分析[J];河北醫(yī)科大學學報;2001年02期

9 王淑莉;劉曉芳;;首診于眼科的頸動脈狹窄患者38例臨床分析[J];中國實用神經(jīng)疾病雜志;2011年11期

10 劉志才;;糖尿病性視神經(jīng)病變臨床分析[J];中國實用神經(jīng)疾病雜志;2011年13期

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