本文選題：CPAP + 口腔矯治器�。� 參考：《山西醫(yī)科大學(xué)》2011年碩士論文

【摘要】：目的：本研究前瞻性比較CPAP和口腔矯治器對阻塞型睡眠呼吸暫停綜合癥患者的治療效果，觀察分析患者治療前后主觀感受、PSG（多導(dǎo)睡眠圖）療效變化、患者治療過程中舒適度及治療選擇傾向，從而探討其臨床療效，為臨床提供指導(dǎo)。 方法：選擇2008.10-2010.10期間就診于山西醫(yī)科大學(xué)第一醫(yī)院呼吸科的中重度OSAS患者30例，將患者隨機分組，分別采用口腔矯治器和CPAP治療，分析比較患者治療6個月后PSG療效及主觀癥狀變化。按照Bonham等提出的有關(guān)OSAS的療效評定標(biāo)準(zhǔn)評價治療效果。實驗數(shù)據(jù)采用SPSS17.0統(tǒng)計學(xué)軟件進行分析。 結(jié)果：CPAP與口腔矯治器治療組前后PSG療效比較發(fā)現(xiàn)：CPAP與口腔矯治器治療組前各指標(biāo)比較差異無統(tǒng)計學(xué)意義；組內(nèi)治療前后各指標(biāo)比較，差異有統(tǒng)計學(xué)意義；CPAP與口腔矯治器組治療后比較差異無統(tǒng)計學(xué)意義。CPAP與口腔矯治器治療組治療前后主觀療效比較：除記憶力減退、晨起頭痛、頭暈、反應(yīng)遲鈍這4項外，P0.05，差異有統(tǒng)計學(xué)意義。CPAP治療組治療前后比較：除記憶力減退、反應(yīng)遲鈍這2項外，P0.05，差異有統(tǒng)計學(xué)意義；口腔矯治器與CPAP治療組治療后各指標(biāo)比較，差異無統(tǒng)計學(xué)意義�？谇怀C治器治療組與CPAP治療組戴用后舒適度比較,差異有統(tǒng)計學(xué)意義。 結(jié)論：（1）兩種治療方法均可用于中重度OSAS的治療，且療效可靠；CPAP與口腔矯治器兩種治療方法療效相近，可以互為替代療法。（2）主觀療效比較CPAP比口腔矯治器更適合治療中重度OSAS患者。（3）口腔矯治器由于其見效快、輕巧、舒適、攜帶方便、價格低，多數(shù)患者更傾向使用。
[Abstract]:Objective: to compare the efficacy of CPAP and oral appliance in the treatment of obstructive sleep apnea syndrome (OSAS), and to observe and analyze the changes of subjective perception of PSG (polysomnography) before and after treatment. In order to explore the clinical effect and provide guidance for clinical treatment, the patients' comfort and treatment choice tendency were discussed in the course of treatment. Methods: thirty patients with moderate and severe OSAS who were admitted to the Department of Respiratory, the first Hospital of Shanxi Medical University from October to October, 2008.were randomly divided into two groups. The patients were treated with oral appliance and CPAP respectively. Objective: to analyze and compare the effect of PSG and the change of subjective symptoms after 6 months of treatment. The efficacy of OSAS was evaluated according to the criteria proposed by Bonham et al. The experimental data were analyzed by SPSS17.0 software. Results there was no significant difference in PSG between the two groups before and after treatment, but there was no significant difference between the two groups before and after treatment. There was no significant difference between CPAP and oral appliance group after treatment. CPAP and oral appliance treatment group before and after treatment of subjective efficacy comparison: except memory loss, morning headache, dizziness, There were significant differences in the four items (P0.05, P 0.05) between the two groups: except memory loss and slowness, there were significant differences between the two groups, and the indexes of oral appliance and CPAP treatment group were compared after treatment. The difference was not statistically significant. There was significant difference between the oral appliance treatment group and the CPAP treatment group after wearing comfort. Conclusion the two methods can be used in the treatment of moderate and severe OSAS, and the curative effect is similar to that of oral appliance. Compared with oral appliance, CPAP is more suitable for treatment of moderate and severe OSAS patients because of its quick effect, light, comfortable, easy to carry and low price. Most patients prefer to use it.
【學(xué)位授予單位】：山西醫(yī)科大學(xué)
【學(xué)位級別】：碩士
【學(xué)位授予年份】：2011
【分類號】：R766

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