眼眶病致眼球突出的病因分析
發(fā)布時(shí)間:2018-03-13 12:18
本文選題:眼球突出 切入點(diǎn):眼眶病 出處:《第四軍醫(yī)大學(xué)》2010年碩士論文 論文類(lèi)型:學(xué)位論文
【摘要】: 目的:了解引起眼球突出的眼眶病的病因分類(lèi)及分布狀態(tài),并對(duì)部分病例的臨床特征進(jìn)行詳細(xì)分析,以期指導(dǎo)臨床診療工作。方法:回顧性分析我院自1960年至2008年收治的583例病歷資料完整的伴有眼球突出的住院患者的臨床資料。對(duì)患者的一般資料、病因、臨床表現(xiàn)、輔助檢查進(jìn)行回顧分析。其中,一般資料包括性別、年齡、病史長(zhǎng)短;臨床表現(xiàn)包括癥狀及體征,如:有無(wú)視力下降、復(fù)視、眼紅、眼痛,有無(wú)斜視、眼球突出、眼球運(yùn)動(dòng)障礙、上瞼下垂、結(jié)膜充血、瞳孔散大等;輔助檢查包括CT、核磁共振、病理檢查等。結(jié)果:引起眼球突出的病因可分為5類(lèi),即腫瘤(58.32%)、內(nèi)分泌疾病(21.44%)、炎癥性疾病(17.15%)、外傷(2.74%)和遺傳及發(fā)育性疾病(0.34%)。根據(jù)來(lái)源可將腫瘤分為眶內(nèi)起源腫瘤(占72.94%)、副鼻竇腫瘤眶蔓延(18.53%)、造血系統(tǒng)腫瘤(4.12%)、顱腦腫瘤眶蔓延(3.24%)、眼內(nèi)腫瘤眶蔓延(0.59%)和轉(zhuǎn)移癌(0.59%)。引起眼球突出的常見(jiàn)病因依次為甲狀腺相關(guān)眼病(21.44%)、海綿狀血管瘤(11.15%)、炎性假瘤(10.29%)、良性腦膜瘤(6.52%)、靜脈性血管瘤(6.00%)、眶蜂窩織炎(5.32%)、皮樣及表皮樣囊腫(4.63%)、神經(jīng)鞘瘤(3.60%)、鱗癌(2.92%)和多形性腺瘤(2.74%)等。引起兒童眼球突出的病因依次為血管瘤、眶蜂窩織炎、皮樣及表皮樣囊腫、腦膜瘤、炎性假瘤、神經(jīng)鞘瘤、神經(jīng)膠質(zhì)瘤、神經(jīng)纖維瘤、甲狀腺相關(guān)性眼病和橫紋肌肉瘤等。結(jié)論:眼球突出可由各種眼眶病引起,單側(cè)眼球突出病因以腫瘤、內(nèi)分泌疾病、炎癥多見(jiàn),成人與兒童眼球突出常見(jiàn)病因不同,兒童以血管瘤多見(jiàn),成人以甲狀腺相關(guān)眼病多見(jiàn)。
[Abstract]:Objective: to investigate the etiological classification and distribution of orbital diseases which cause exophthalmos, and to analyze the clinical characteristics of some cases in detail. Methods: the clinical data of 583 inpatients with exophthalmos were analyzed retrospectively from 1960 to 2008. The general data, etiology and clinical manifestations of the patients were analyzed. The general data include gender, age, history, symptoms and signs, such as vision loss, diplopia, eye redness, eye pain, strabismus, exophthalmos, etc. Ocular movement disorder, blepharoptosis, conjunctival hyperemia, pupil dilatation, etc. Auxiliary examinations include CTS, MRI, pathological examination, etc. Results: the causes of exophthalmos can be classified into 5 categories. That is, tumor 58.32m, endocrine disease 21.4445, inflammatory disease 17.15, trauma 2.74) and genetic and developmental diseases 0.344.The tumors can be divided into intraorbital origin tumors (72.94%), paranasal sinus tumors (18.53%), hematopoietic system tumors (4.1212%), craniocerebral tumor orbital tumors (72.94%), hematopoietic system tumors (4.1212%), craniocerebral tumor orbital tumors (72.94%), tumors of paranasal sinuses (18.53%), hematopoietic system tumors (4.1212%). The common causes of ophthalmic exophthalmos are thyroid associated ophthalmopathy (21.44), cavernous hemangioma (11.1515), inflammatory pseudotumor (10.29), benign meningioma (6.52), venous angioma (6.00), orbital cellulitis (5.32), dermoid. And epidermoid cysts 4.63%, schwannoma 3.60%, squamous cell carcinoma 2.92% and pleomorphic adenoma 2.74). Orbital cellulitis, dermoid and epidermoid cyst, meningioma, inflammatory pseudotumor, neurilemmoma, glioma, neurofibroma, thyroid associated ophthalmopathy and rhabdomyosarcoma. The common causes of unilateral exophthalmos were tumor, endocrine diseases and inflammation. The common causes were different between adults and children. Hemangioma was more common in children, thyroid associated ophthalmopathy was more common in adults.
【學(xué)位授予單位】:第四軍醫(yī)大學(xué)
【學(xué)位級(jí)別】:碩士
【學(xué)位授予年份】:2010
【分類(lèi)號(hào)】:R777
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